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miRTarBase - #MIRT670177 -
pre-miRNA Information
pre-miRNA hsa-mir-122   
Genomic Coordinates chr18: 58451074 - 58451158
Synonyms MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, MIR122
Description Homo sapiens miR-122 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-122-5p
Sequence 15| UGGAGUGUGACAAUGGUGUUUG |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 18 + 58451091 29233923 MiREDiBase
C-to-U 11 18 + 58451098 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1258166649 1 dbSNP
rs1426570658 6 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CCDC142   
Synonyms -
Description coiled-coil domain containing 142
Transcript NM_032779   
Expression
Putative miRNA Targets on CCDC142
3'UTR of CCDC142
(miRNA target sites are highlighted)		 
>CCDC142|NM_032779|3'UTR
   1 GGAGCCTGGGACCAGGAGCCAGAAAGTTAAGAGCTCCCCATCTCTAGCTGGAAAATCCAGACATTTGGAATTGCATATTA
  81 AGGAAGCCCAGAACTGGAAGCTTGGAGGAAAGCATACTGGAGAATAAGCTACAAAGAGCCTGGGCTTAAGAATCCAAGAT
 161 TAGGGGCTGGGCGAGGTGGCTCACGCCTGTAATCCAGCACTTTGGGAGACCGAGGCAGGCGGATCATGAGGTCAGGAGAT
 241 CAAGACCATCCTGGCTAACACGGTGAAACCCTGTTTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGTGCC
 321 TGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCTGAGATCC
 401 AGCCACAGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAATCCAAGATTAGGCAGG
 481 GCATGGTGGCTCACACCTATAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACCTGAGGTCGGGAGTTCCAGACC
 561 AGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGGCGCATGCCTGTAATCCC
 641 AGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTAGGAGGCGAAGGTTGCGGAGAGCCGAGATTGTGCCATTGC
 721 ACTCCAGCCTGGGCAACAAGGGCAAAACTTCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAATCCAAGATCACTCCAGCA
 801 CCTGGAATCCAGAGTAAAGAGCAAGACCATAGCCTGGAACCTGAAGGTCAGACCCTTGGGAGGTTCAGGCCTAGTTCTCC
 881 ATCACTGAAGATATCTCAGGGATAAAGAGTTGAGTGCTCGGCCAGGTGAGGGGGCTCACGCCTGCTCACGCCTGTAATCC
 961 CAGCACTTTGGGAGGCCTAGAGGGGCGGATCACGAGGTCCGATCAAGACCATCCTGGCTAACGCGGTGAAACCCCGCCTC
1041 TACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCACGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCATGAGAA
1121 TCGCTTGAACCCGGGAGGCAGAGATTGCAGTGAGCCGAGATCGCGCCACTGCACTCCTGCCTGGGCAACAAGAGCAAAAC
1201 TTCGTCTCAAAAAAAGAAAACTGGCTAGAATGCACTTCAACTTAAGTCCTGGGAGCTACGCTAATTCATGGAGAACCACA
1281 GAGGTTTAATAGGCATTTCTATACCTGGATCAGCCCCAAGGACAGTATTACCCTGTACTGCCCTTCCTATTACTATTTTC
1361 AGTCATTTACTAATATTGGGCTGTAGTACTTTCACGTTTAAGCTTTGGCTATTCAGAGCTCACTACGTTTAATCTTCAGT
1441 TACCTGAATGGTGTTTACCTTCTGGTGTGGATCATCCCGGCTTGTGTTAGTGCTCTCTCTTTGGAAGAAGCCAGGATTTA
1521 AGATCGAGTTAGCCTAGATGTGGCCCAGCAGGGTACAGAAGGGGAAAGGCTGCAGAAAACGGGCGTATTTTCGTGCAAAG
1601 AGGTTTTTGCGCCATTTATTTATGGTTTTCACCGTCGTATGAGAGGACTATTCATGATAGGCTGTATTTGCTGACAGCCT
1681 ACTTTGGGCTCCCCCATGCGTTGTGCCGAAACCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1 
miRNA  3' guuUGUGGUAACAGUGUGAGGu 5'
             :::|||||   :|||||| 
Target 5' attGTGCCATT---GCACTCCa 3'
 		708 - 726 140.00 -17.50
2 
miRNA  3' guuUGUGGUAACAGUGUGAGGu 5'
             :|:||| |   :|||||| 
Target 5' atcGCGCCACT---GCACTCCt 3'
 		1160 - 1178 136.00 -15.60
3 
miRNA  3' guuugugguaacagUGUGAGGu 5'
                        :|||||| 
Target 5' gagatccagccacaGCACTCCa 3'
 		394 - 415 124.00 -15.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30468742 8 COSMIC
COSN30154435 16 COSMIC
COSN30496585 34 COSMIC
COSN30525807 36 COSMIC
COSN30474868 58 COSMIC
COSN19256329 83 COSMIC
COSN31559717 113 COSMIC
COSN31500257 138 COSMIC
COSN21649750 346 COSMIC
COSN18778330 444 COSMIC
COSM9101092 586 COSMIC
COSN17078492 657 COSMIC
COSN7082991 1432 COSMIC
COSN27163487 1525 COSMIC
COSM4164586 1630 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs769392763 4 dbSNP
rs745480815 5 dbSNP
rs1365894690 6 dbSNP
rs1318126376 7 dbSNP
rs766888214 10 dbSNP
rs1240502115 11 dbSNP
rs1213211276 12 dbSNP
rs780857185 15 dbSNP
rs180792036 16 dbSNP
rs758265593 18 dbSNP
rs1309676799 19 dbSNP
rs371886895 20 dbSNP
rs368450432 21 dbSNP
rs779977284 23 dbSNP
rs374532838 26 dbSNP
rs756246933 34 dbSNP
rs1162866391 36 dbSNP
rs750622503 37 dbSNP
rs1417145578 39 dbSNP
rs1461868828 49 dbSNP
rs188435383 60 dbSNP
rs1352482876 62 dbSNP
rs879235181 67 dbSNP
rs1461174152 70 dbSNP
rs1003696017 73 dbSNP
rs1375052914 77 dbSNP
rs1032377540 80 dbSNP
rs1412437608 100 dbSNP
rs1000866090 101 dbSNP
rs905134659 102 dbSNP
rs1041495648 109 dbSNP
rs1306060984 111 dbSNP
rs1009950126 128 dbSNP
rs370794146 130 dbSNP
rs538523273 131 dbSNP
rs1299930248 137 dbSNP
rs1451036353 142 dbSNP
rs1344046147 145 dbSNP
rs1044992090 146 dbSNP
rs1165056934 148 dbSNP
rs1481729783 153 dbSNP
rs892822030 161 dbSNP
rs1054500564 175 dbSNP
rs537038671 182 dbSNP
rs1013442681 184 dbSNP
rs896268714 185 dbSNP
rs1046818847 197 dbSNP
rs1427760193 205 dbSNP
rs567798366 211 dbSNP
rs919680851 212 dbSNP
rs1432436044 215 dbSNP
rs867805746 217 dbSNP
rs376916232 218 dbSNP
rs1375462964 220 dbSNP
rs534362179 221 dbSNP
rs1188761171 223 dbSNP
rs566985362 231 dbSNP
rs767891270 233 dbSNP
rs1214402873 241 dbSNP
rs1296703229 242 dbSNP
rs1309520782 249 dbSNP
rs1260155085 256 dbSNP
rs551859314 261 dbSNP
rs944536511 263 dbSNP
rs1486075901 265 dbSNP
rs933508580 270 dbSNP
rs1232500317 272 dbSNP
rs1240335157 273 dbSNP
rs1475024709 281 dbSNP
rs1186919114 286 dbSNP
rs923401972 287 dbSNP
rs1297668686 288 dbSNP
rs1380401016 290 dbSNP
rs1360666061 295 dbSNP
rs1172559424 296 dbSNP
rs1395305376 296 dbSNP
rs1293675323 298 dbSNP
rs533172945 300 dbSNP
rs988319488 301 dbSNP
rs957046306 302 dbSNP
rs1343994990 305 dbSNP
rs569229455 311 dbSNP
rs952206431 313 dbSNP
rs1032410289 314 dbSNP
rs979457478 315 dbSNP
rs1461275559 316 dbSNP
rs920620114 319 dbSNP
rs1303019667 320 dbSNP
rs991215468 321 dbSNP
rs1221054399 328 dbSNP
rs969352698 332 dbSNP
rs1446379639 337 dbSNP
rs1023558693 338 dbSNP
rs1035269216 342 dbSNP
rs1013886121 350 dbSNP
rs1253293082 351 dbSNP
rs1003762878 355 dbSNP
rs1156337814 359 dbSNP
rs1427184538 372 dbSNP
rs1400638903 376 dbSNP
rs10211358 377 dbSNP
rs1191899455 380 dbSNP
rs1439219864 384 dbSNP
rs1325611425 393 dbSNP
rs1372039487 415 dbSNP
rs75865964 418 dbSNP
rs1277867511 423 dbSNP
rs1469857014 430 dbSNP
rs1251410209 432 dbSNP
rs1270003874 433 dbSNP
rs1332563078 438 dbSNP
rs1212885228 440 dbSNP
rs1273542960 442 dbSNP
rs1213249687 443 dbSNP
rs1267992649 444 dbSNP
rs869038525 445 dbSNP
rs1179157985 462 dbSNP
rs1021109905 465 dbSNP
rs1164687316 465 dbSNP
rs1178405123 465 dbSNP
rs1335386681 465 dbSNP
rs1414884892 465 dbSNP
rs1431734147 465 dbSNP
rs1470248381 465 dbSNP
rs36104438 465 dbSNP
rs1010001678 477 dbSNP
rs942411832 487 dbSNP
rs892862456 492 dbSNP
rs1353521661 496 dbSNP
rs80130461 497 dbSNP
rs1306905289 515 dbSNP
rs1054149949 519 dbSNP
rs996240561 520 dbSNP
rs1193841560 523 dbSNP
rs1235902755 531 dbSNP
rs192706789 532 dbSNP
rs1206720643 536 dbSNP
rs370051180 545 dbSNP
rs1474519522 546 dbSNP
rs1187772057 547 dbSNP
rs1324826417 550 dbSNP
rs986554225 552 dbSNP
rs1446988542 555 dbSNP
rs1397656445 556 dbSNP
rs1300335032 560 dbSNP
rs190071582 564 dbSNP
rs1166494168 569 dbSNP
rs1349715119 572 dbSNP
rs900449112 575 dbSNP
rs1373054034 577 dbSNP
rs1373652802 579 dbSNP
rs542432394 585 dbSNP
rs1040276994 586 dbSNP
rs944588794 595 dbSNP
rs907734602 604 dbSNP
rs1047528662 607 dbSNP
rs1193248409 613 dbSNP
rs1230084163 614 dbSNP
rs1440622475 616 dbSNP
rs1252910962 624 dbSNP
rs766513440 624 dbSNP
rs527445621 625 dbSNP
rs1480168536 626 dbSNP
rs1256547081 627 dbSNP
rs1212870871 636 dbSNP
rs1191528329 638 dbSNP
rs1372821768 639 dbSNP
rs1345133833 643 dbSNP
rs559821151 646 dbSNP
rs1170648773 648 dbSNP
rs1240231591 649 dbSNP
rs1434235535 657 dbSNP
rs1337216595 659 dbSNP
rs920658127 666 dbSNP
rs990876187 670 dbSNP
rs1317392261 671 dbSNP
rs1326734635 687 dbSNP
rs1230328951 688 dbSNP
rs959629807 692 dbSNP
rs377643409 696 dbSNP
rs1396169563 697 dbSNP
rs1314036752 698 dbSNP
rs1437055166 704 dbSNP
rs1374169983 705 dbSNP
rs1261479772 710 dbSNP
rs1465686903 716 dbSNP
rs927910036 720 dbSNP
rs1251412798 728 dbSNP
rs1453957306 732 dbSNP
rs982378696 738 dbSNP
rs1379384727 740 dbSNP
rs1157990118 741 dbSNP
rs1385561486 742 dbSNP
rs1437073322 743 dbSNP
rs1323610394 746 dbSNP
rs1173159146 748 dbSNP
rs1440371844 752 dbSNP
rs1369830444 754 dbSNP
rs185231515 755 dbSNP
rs1179871858 756 dbSNP
rs1302789085 756 dbSNP
rs1237701483 757 dbSNP
rs1260717117 757 dbSNP
rs1418306174 758 dbSNP
rs1256519627 759 dbSNP
rs1271603759 769 dbSNP
rs1468215066 773 dbSNP
rs1189985198 777 dbSNP
rs1191920549 779 dbSNP
rs1417465237 782 dbSNP
rs1162556222 783 dbSNP
rs1181148842 783 dbSNP
rs1186805026 783 dbSNP
rs1222753701 783 dbSNP
rs1230711491 783 dbSNP
rs1291826525 783 dbSNP
rs1294997959 783 dbSNP
rs1307031793 783 dbSNP
rs1334683552 783 dbSNP
rs1351667433 783 dbSNP
rs1370713342 783 dbSNP
rs138815406 783 dbSNP
rs1390351980 783 dbSNP
rs1393387344 783 dbSNP
rs1412671935 783 dbSNP
rs1458102451 783 dbSNP
rs1491236312 783 dbSNP
rs34305895 783 dbSNP
rs1185629270 784 dbSNP
rs1195332239 784 dbSNP
rs1479763282 784 dbSNP
rs1484686535 784 dbSNP
rs1491257105 784 dbSNP
rs1417077334 785 dbSNP
rs1424242383 788 dbSNP
rs577608479 793 dbSNP
rs1279503160 794 dbSNP
rs1352430045 799 dbSNP
rs1461127030 801 dbSNP
rs896395888 805 dbSNP
rs1308120887 812 dbSNP
rs1371795637 813 dbSNP
rs1216760066 814 dbSNP
rs1412378582 815 dbSNP
rs1025935288 819 dbSNP
rs1258610673 820 dbSNP
rs1237812196 828 dbSNP
rs1335552633 832 dbSNP
rs1294361838 841 dbSNP
rs1229291993 846 dbSNP
rs1416996611 847 dbSNP
rs966922037 854 dbSNP
rs1021162312 856 dbSNP
rs1226900292 863 dbSNP
rs1275453015 864 dbSNP
rs1484116865 866 dbSNP
rs1011471610 867 dbSNP
rs1354167282 868 dbSNP
rs1312771795 875 dbSNP
rs957181063 885 dbSNP
rs1401389958 889 dbSNP
rs1033166283 893 dbSNP
rs995904388 895 dbSNP
rs1391616221 900 dbSNP
rs1432383531 907 dbSNP
rs1311709531 912 dbSNP
rs1359128008 917 dbSNP
rs900181689 919 dbSNP
rs1157057641 927 dbSNP
rs993994756 928 dbSNP
rs1418837981 929 dbSNP
rs1166898364 931 dbSNP
rs1360230773 936 dbSNP
rs1018544199 937 dbSNP
rs898266294 939 dbSNP
rs1256762306 940 dbSNP
rs1232237202 943 dbSNP
rs1038054845 945 dbSNP
rs942389408 949 dbSNP
rs889412912 950 dbSNP
rs1312711485 951 dbSNP
rs774559470 953 dbSNP
rs1448240629 955 dbSNP
rs1487935866 955 dbSNP
rs1188941206 961 dbSNP
rs1258976732 963 dbSNP
rs1452142035 964 dbSNP
rs1172501816 971 dbSNP
rs1204033451 976 dbSNP
rs1178957084 982 dbSNP
rs1415551856 982 dbSNP
rs933604358 986 dbSNP
rs1457093558 990 dbSNP
rs923544694 993 dbSNP
rs1367645093 994 dbSNP
rs1438901688 996 dbSNP
rs1274339083 1000 dbSNP
rs988739120 1001 dbSNP
rs935500904 1006 dbSNP
rs1221002433 1007 dbSNP
rs1282122271 1009 dbSNP
rs1328350341 1012 dbSNP
rs556110174 1017 dbSNP
rs979471857 1022 dbSNP
rs969385200 1023 dbSNP
rs1293235810 1024 dbSNP
rs951182932 1031 dbSNP
rs899282687 1032 dbSNP
rs544604941 1033 dbSNP
rs1023674820 1036 dbSNP
rs992169548 1037 dbSNP
rs1316395395 1045 dbSNP
rs760749694 1049 dbSNP
rs1055619986 1051 dbSNP
rs960929176 1052 dbSNP
rs1025545373 1053 dbSNP
rs193225742 1057 dbSNP
rs1167325790 1059 dbSNP
rs375759411 1060 dbSNP
rs377306440 1064 dbSNP
rs1416829427 1065 dbSNP
rs1323208057 1067 dbSNP
rs1168433806 1068 dbSNP
rs567023905 1071 dbSNP
rs1016642949 1079 dbSNP
rs1476390176 1079 dbSNP
rs1371253364 1080 dbSNP
rs1349819900 1081 dbSNP
rs1228872180 1082 dbSNP
rs1289989546 1083 dbSNP
rs1191911914 1088 dbSNP
rs1332498597 1090 dbSNP
rs1006563631 1091 dbSNP
rs889526911 1092 dbSNP
rs371205175 1097 dbSNP
rs564100906 1101 dbSNP
rs1272865976 1103 dbSNP
rs902122831 1107 dbSNP
rs1183614502 1108 dbSNP
rs1414815063 1115 dbSNP
rs533004852 1118 dbSNP
rs1474458171 1127 dbSNP
rs539912277 1130 dbSNP
rs1342153751 1131 dbSNP
rs935499914 1132 dbSNP
rs569190969 1133 dbSNP
rs1043909246 1137 dbSNP
rs948157120 1144 dbSNP
rs1018596552 1145 dbSNP
rs1309842344 1152 dbSNP
rs916647055 1156 dbSNP
rs545801523 1157 dbSNP
rs529238618 1159 dbSNP
rs187679799 1162 dbSNP
rs1371760189 1164 dbSNP
rs1243849679 1165 dbSNP
rs1358059120 1166 dbSNP
rs1212363538 1167 dbSNP
rs183406812 1169 dbSNP
rs767808008 1174 dbSNP
rs1483128372 1176 dbSNP
rs918516317 1183 dbSNP
rs1206650307 1192 dbSNP
rs191245557 1203 dbSNP
rs527533201 1204 dbSNP
rs1238354746 1213 dbSNP
rs1473900873 1215 dbSNP
rs17009955 1222 dbSNP
rs886397880 1222 dbSNP
rs1016760794 1224 dbSNP
rs1411428880 1225 dbSNP
rs899011771 1227 dbSNP
rs1006678374 1232 dbSNP
rs1334566441 1243 dbSNP
rs938106002 1244 dbSNP
rs139444785 1246 dbSNP
rs1257344584 1248 dbSNP
rs146276731 1253 dbSNP
rs1454349313 1256 dbSNP
rs1046470239 1260 dbSNP
rs1396300933 1261 dbSNP
rs763070435 1262 dbSNP
rs1453487068 1275 dbSNP
rs891439085 1278 dbSNP
rs562414139 1283 dbSNP
rs1343509766 1312 dbSNP
rs945349538 1317 dbSNP
rs1257477019 1318 dbSNP
rs1444553831 1332 dbSNP
rs1053124164 1339 dbSNP
rs544208048 1340 dbSNP
rs775478613 1343 dbSNP
rs1233081937 1352 dbSNP
rs1450285124 1358 dbSNP
rs1205717981 1359 dbSNP
rs1375946596 1371 dbSNP
rs999813068 1378 dbSNP
rs573635972 1384 dbSNP
rs1173145017 1385 dbSNP
rs1271536963 1389 dbSNP
rs1398773753 1393 dbSNP
rs1195676451 1396 dbSNP
rs1348698895 1407 dbSNP
rs1319596309 1411 dbSNP
rs1305810418 1420 dbSNP
rs1436753577 1427 dbSNP
rs1300632420 1431 dbSNP
rs141818840 1431 dbSNP
rs1370594744 1433 dbSNP
rs1233325359 1434 dbSNP
rs1257149532 1439 dbSNP
rs921447617 1451 dbSNP
rs139465854 1459 dbSNP
rs770865531 1460 dbSNP
rs1267847008 1461 dbSNP
rs1465528921 1462 dbSNP
rs1210888236 1466 dbSNP
rs1265516845 1470 dbSNP
rs1432720506 1472 dbSNP
rs1352494389 1476 dbSNP
rs1328115982 1481 dbSNP
rs13403485 1483 dbSNP
rs1056528003 1487 dbSNP
rs1379330561 1492 dbSNP
rs1018647335 1493 dbSNP
rs558314776 1494 dbSNP
rs1158165222 1499 dbSNP
rs566944658 1501 dbSNP
rs1458613276 1512 dbSNP
rs377091910 1514 dbSNP
rs973137721 1516 dbSNP
rs962642753 1517 dbSNP
rs909787744 1539 dbSNP
rs1386892320 1541 dbSNP
rs1302697978 1543 dbSNP
rs1333361049 1549 dbSNP
rs1178529826 1553 dbSNP
rs1288126773 1559 dbSNP
rs1025954645 1561 dbSNP
rs186823767 1564 dbSNP
rs953854521 1572 dbSNP
rs1029845469 1581 dbSNP
rs1002032833 1583 dbSNP
rs906647640 1584 dbSNP
rs879359768 1585 dbSNP
rs1412616235 1597 dbSNP
rs1486318634 1610 dbSNP
rs1473472922 1614 dbSNP
rs1162403241 1615 dbSNP
rs1367550861 1620 dbSNP
rs575709548 1633 dbSNP
rs1294775428 1636 dbSNP
rs183078378 1642 dbSNP
rs1311639345 1644 dbSNP
rs567858605 1649 dbSNP
rs1408688912 1650 dbSNP
rs535459657 1651 dbSNP
rs892481531 1655 dbSNP
rs1031373561 1658 dbSNP
rs72907224 1660 dbSNP
rs904134479 1664 dbSNP
rs1310980220 1668 dbSNP
rs1043972397 1670 dbSNP
rs1245723414 1672 dbSNP
rs1225622337 1675 dbSNP
rs1370914019 1682 dbSNP
rs548909444 1689 dbSNP
rs936951365 1691 dbSNP
rs973935320 1693 dbSNP
rs921510162 1694 dbSNP
rs534684040 1699 dbSNP
rs1012438316 1700 dbSNP
rs895275952 1704 dbSNP
rs1424038613 1708 dbSNP
rs878914956 1711 dbSNP
rs1428605915 1713 dbSNP
rs944202474 1715 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084047. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep4 ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
IDDuplex structurePosition
1 
miRNA  3' guuugugguaacagUGUGAGGu 5'
                        :|||||| 
Target 5' ------------caGCACUCCa 3'
 		1 - 10
2 
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            :::: ||  |  | ||||: 
Target 5' ugGGUGACAGAGCAAGACUCUg 3'
 		14 - 35
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084047
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep4
Location of target site ENST00000393965.3 | 3UTR | CAGCACUCCAGCCUGGGUGACAGAGCAAGACUCUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE38226 Liver fibrosis 0.647 7.6e-4 0.609 1.7e-3 21 Click to see details
GSE28544 Breast cancer 0.525 4.2e-3 0.638 4.0e-4 24 Click to see details
GSE28260 Renal cortex and medulla -0.679 5.4e-3 -0.648 8.3e-3 13 Click to see details
GSE26953 Aortic valvular endothelial cells -0.331 5.7e-2 -0.217 1.5e-1 24 Click to see details
GSE21687 Ependynoma primary tumors -0.148 1.2e-1 -0.129 1.5e-1 64 Click to see details
GSE17306 Multiple myeloma 0.13 1.9e-1 0.147 1.6e-1 49 Click to see details
GSE21849 B cell lymphoma -0.169 1.9e-1 0.131 2.5e-1 29 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.396 2.2e-1 0.600 1.0e-1 6 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.151 2.4e-1 0.112 3.0e-1 25 Click to see details
GSE14794 Lymphoblastoid cells 0.071 2.5e-1 0.123 1.2e-1 90 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.14 2.8e-1 -0.051 4.2e-1 20 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.105 3.1e-1 -0.136 2.6e-1 25 Click to see details
GSE27834 Pluripotent stem cells -0.123 3.2e-1 -0.147 2.9e-1 16 Click to see details
GSE32688 Pancreatic cancer -0.034 4.3e-1 -0.200 1.4e-1 32 Click to see details
GSE19350 CNS germ cell tumors -0.029 4.6e-1 0.213 2.5e-1 12 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
KIRP 0.441 0.12 -0.017 0.48 9 Click to see details
KICH -0.454 0.13 -0.595 0.06 8 Click to see details
LIHC 0.154 0.15 -0.021 0.44 49 Click to see details
HNSC -0.889 0.15 -0.500 0.33 3 Click to see details
STAD 0.359 0.19 0.143 0.37 8 Click to see details
ESCA 0.454 0.22 0.300 0.31 5 Click to see details
THCA 0.451 0.22 0.300 0.31 5 Click to see details
CHOL 0.229 0.28 0.017 0.48 9 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
KIRC -0.096 0.31 0.078 0.34 29 Click to see details
MiRNA Regulatory Network:
Functional analysis:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR) Other evidence
Transcription factor regulation Circular RNA sponge
539 hsa-miR-122-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000012 CYP7A1 cytochrome P450 family 7 subfamily A member 1 3 1
MIRT000364 IGF1R insulin like growth factor 1 receptor 4 3
MIRT000365 SRF serum response factor 4 1
MIRT000663 RAC1 Rac family small GTPase 1 5 2
MIRT000717 RHOA ras homolog family member A 2 2
MIRT003006 CCNG1 cyclin G1 4 4
MIRT003079 GTF2B general transcription factor IIB 2 1
MIRT003080 GYS1 glycogen synthase 1 4 2
MIRT003081 ANK2 ankyrin 2 3 1
MIRT003082 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 3 1
MIRT003083 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 4 2
MIRT003084 ANXA11 annexin A11 4 2
MIRT003085 ALDOA aldolase, fructose-bisphosphate A 3 2
MIRT003086 RAB6B RAB6B, member RAS oncogene family 3 1
MIRT003087 RAB11FIP1 RAB11 family interacting protein 1 5 3
MIRT003088 FOXP1 forkhead box P1 3 1
MIRT003089 MECP2 methyl-CpG binding protein 2 3 2
MIRT003090 NCAM1 neural cell adhesion molecule 1 4 3
MIRT003091 UBAP2 ubiquitin associated protein 2 3 1
MIRT003092 TBX19 T-box 19 3 1
MIRT003093 AACS acetoacetyl-CoA synthetase 3 1
MIRT003094 DUSP2 dual specificity phosphatase 2 3 1
MIRT003095 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 3 1
MIRT003097 MAPK11 mitogen-activated protein kinase 11 3 1
MIRT003098 FUNDC2 FUN14 domain containing 2 3 1
MIRT003099 AKT3 AKT serine/threonine kinase 3 3 3
MIRT003100 TPD52L2 tumor protein D52 like 2 4 3
MIRT003102 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 4 2
MIRT003103 G6PC3 glucose-6-phosphatase catalytic subunit 3 4 2
MIRT003104 AP3M2 adaptor related protein complex 3 mu 2 subunit 3 1
MIRT003105 SLC7A1 solute carrier family 7 member 1 4 4
MIRT003106 XPO6 exportin 6 3 1
MIRT003107 FOXJ3 forkhead box J3 3 1
MIRT003108 SLC7A11 solute carrier family 7 member 11 3 1
MIRT003109 TRIB1 tribbles pseudokinase 1 3 1
MIRT003110 EGLN3 egl-9 family hypoxia inducible factor 3 3 1
MIRT003111 NUMBL NUMB like, endocytic adaptor protein 3 1
MIRT003112 ADAM17 ADAM metallopeptidase domain 17 3 5
MIRT003727 DSTYK dual serine/threonine and tyrosine protein kinase 3 2
MIRT003728 FAM117B family with sequence similarity 117 member B 3 1
MIRT004364 BCL2L2 BCL2 like 2 4 2
MIRT004527 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 2 1
MIRT004879 ADAM10 ADAM metallopeptidase domain 10 5 1
MIRT005782 ACVR1C activin A receptor type 1C 1 1
MIRT006123 PRKRA protein activator of interferon induced protein kinase EIF2AK2 4 1
MIRT006421 WNT1 Wnt family member 1 3 1
MIRT007007 PTPN1 protein tyrosine phosphatase, non-receptor type 1 1 1
MIRT007081 NT5C3A 5'-nucleotidase, cytosolic IIIA 1 1
MIRT007082 P4HA1 prolyl 4-hydroxylase subunit alpha 1 1 1
MIRT007083 ZNF395 zinc finger protein 395 1 1
MIRT007084 SOCS1 suppressor of cytokine signaling 1 1 1
MIRT023217 SSR3 signal sequence receptor subunit 3 1 1
MIRT023218 PHOX2A paired like homeobox 2a 1 1
MIRT023219 DZIP1L DAZ interacting zinc finger protein 1 like 1 1
MIRT023220 GSTM2 glutathione S-transferase mu 2 1 1
MIRT023221 RAI14 retinoic acid induced 14 1 1
MIRT023222 STARD13 StAR related lipid transfer domain containing 13 1 1
MIRT023223 CNN3 calponin 3 1 1
MIRT023224 A2M alpha-2-macroglobulin 1 1
MIRT023225 EFCAB6 EF-hand calcium binding domain 6 1 1
MIRT023226 GLOD4 glyoxalase domain containing 4 1 1
MIRT023227 CALR calreticulin 1 1
MIRT023228 POFUT1 protein O-fucosyltransferase 1 1 1
MIRT023229 PYGO1 pygopus family PHD finger 1 1 1
MIRT023230 CDY2B chromodomain Y-linked 2B 1 1
MIRT023231 CDC42EP3 CDC42 effector protein 3 1 1
MIRT023232 CS citrate synthase 3 3
MIRT023233 RNF170 ring finger protein 170 3 3
MIRT023234 GTF3C6 general transcription factor IIIC subunit 6 1 1
MIRT023235 ZNF321P zinc finger protein 321, pseudogene 1 1
MIRT023236 LAMP1 lysosomal associated membrane protein 1 1 1
MIRT023237 SLC52A2 solute carrier family 52 member 2 1 1
MIRT023238 ZNF658 zinc finger protein 658 1 1
MIRT023239 ATP13A3 ATPase 13A3 1 1
MIRT023240 CPNE5 copine 5 1 1
MIRT023241 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT023242 TMEM136 transmembrane protein 136 1 1
MIRT023243 ATP11A ATPase phospholipid transporting 11A 1 1
MIRT023244 TMEM74 transmembrane protein 74 1 1
MIRT023245 ANKRD10 ankyrin repeat domain 10 1 1
MIRT023246 TBL1XR1 transducin beta like 1 X-linked receptor 1 1 1
MIRT023247 USP10 ubiquitin specific peptidase 10 1 1
MIRT023248 AKAP11 A-kinase anchoring protein 11 1 1
MIRT023249 BACH2 BTB domain and CNC homolog 2 1 1
MIRT023250 HCCS holocytochrome c synthase 1 1
MIRT023251 Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1 1
MIRT023252 GTDC2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1 1
MIRT023253 CTPS1 CTP synthase 1 1 1
MIRT023254 SLC44A1 solute carrier family 44 member 1 1 1
MIRT023255 CLSPN claspin 1 1
MIRT023256 RABGEF1 RAB guanine nucleotide exchange factor 1 1 1
MIRT023257 FBXO7 F-box protein 7 1 1
MIRT023258 NCDN neurochondrin 1 1
MIRT023259 SOX2 SRY-box 2 1 1
MIRT023260 ZNF618 zinc finger protein 618 1 1
MIRT023261 ABLIM1 actin binding LIM protein 1 1 1
MIRT023262 ZBTB4 zinc finger and BTB domain containing 4 1 1
MIRT023263 LUZP1 leucine zipper protein 1 1 1
MIRT023264 NLGN3 neuroligin 3 1 1
MIRT023265 PRR11 proline rich 11 1 1
MIRT023266 HHAT hedgehog acyltransferase 1 1
MIRT023267 UBE2L3 ubiquitin conjugating enzyme E2 L3 1 1
MIRT023268 DNAJC18 DnaJ heat shock protein family (Hsp40) member C18 1 1
MIRT023269 FAM102A family with sequence similarity 102 member A 1 1
MIRT023270 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT023271 DENND2C DENN domain containing 2C 1 1
MIRT023272 HMOX1 heme oxygenase 1 3 2
MIRT023273 USP28 ubiquitin specific peptidase 28 1 1
MIRT023274 KRT18 keratin 18 1 1
MIRT023275 BPGM bisphosphoglycerate mutase 1 1
MIRT023276 ZNF233 zinc finger protein 233 1 1
MIRT023277 SLC25A30 solute carrier family 25 member 30 1 1
MIRT023278 ANKRD9 ankyrin repeat domain 9 3 3
MIRT023279 RLN1 relaxin 1 1 1
MIRT023280 DDIT3 DNA damage inducible transcript 3 1 1
MIRT023281 TRIM65 tripartite motif containing 65 1 1
MIRT023282 B4GALT1 beta-1,4-galactosyltransferase 1 1 1
MIRT023283 ANXA7 annexin A7 1 1
MIRT023284 SLC19A2 solute carrier family 19 member 2 1 1
MIRT023285 MARCKS myristoylated alanine rich protein kinase C substrate 1 1
MIRT023286 CLEC11A C-type lectin domain containing 11A 1 1
MIRT023287 CENPF centromere protein F 1 1
MIRT023288 CLDN18 claudin 18 1 1
MIRT023289 PFDN1 prefoldin subunit 1 1 1
MIRT023290 SPAG9 sperm associated antigen 9 1 1
MIRT023291 CEACAM8 carcinoembryonic antigen related cell adhesion molecule 8 1 1
MIRT023292 KRT10 keratin 10 1 1
MIRT023293 SET SET nuclear proto-oncogene 1 1
MIRT023294 SLC11A2 solute carrier family 11 member 2 1 1
MIRT023295 MYCBP MYC binding protein 3 3
MIRT023296 GPHB5 glycoprotein hormone beta 5 1 1
MIRT023297 STAU2 staufen double-stranded RNA binding protein 2 1 1
MIRT023298 NFATC1 nuclear factor of activated T-cells 1 1 1
MIRT023299 ERP29 endoplasmic reticulum protein 29 1 1
MIRT023300 MEP1A meprin A subunit alpha 1 1
MIRT023301 SPTLC1 serine palmitoyltransferase long chain base subunit 1 1 1
MIRT023302 GTF2H2 general transcription factor IIH subunit 2 1 1
MIRT023303 C14orf39 chromosome 14 open reading frame 39 1 1
MIRT023304 UBE2K ubiquitin conjugating enzyme E2 K 1 1
MIRT023305 PPP1R9B protein phosphatase 1 regulatory subunit 9B 1 1
MIRT023306 PSMD10 proteasome 26S subunit, non-ATPase 10 1 1
MIRT023307 CALD1 caldesmon 1 1 1
MIRT023308 TTYH3 tweety family member 3 1 1
MIRT023309 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 1 1
MIRT023310 SCN4B sodium voltage-gated channel beta subunit 4 1 1
MIRT023311 C1orf122 chromosome 1 open reading frame 122 1 1
MIRT023312 PAK1 p21 (RAC1) activated kinase 1 1 1
MIRT023313 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 1 1
MIRT023314 DMXL1 Dmx like 1 1 1
MIRT023315 ZNF160 zinc finger protein 160 1 1
MIRT023316 CSRP1 cysteine and glycine rich protein 1 1 1
MIRT023317 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT023318 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 1 1
MIRT023319 ANKRD13C ankyrin repeat domain 13C 1 1
MIRT023320 SUCLA2 succinate-CoA ligase ADP-forming beta subunit 1 1
MIRT023321 PEA15 phosphoprotein enriched in astrocytes 15 1 1
MIRT023322 MTPN myotrophin 1 1
MIRT023323 YKT6 YKT6 v-SNARE homolog 1 1
MIRT023324 MOB3B MOB kinase activator 3B 1 1
MIRT023325 FAM118A family with sequence similarity 118 member A 1 1
MIRT023326 ZNF264 zinc finger protein 264 1 1
MIRT023327 HECTD3 HECT domain E3 ubiquitin protein ligase 3 1 1
MIRT023328 BATF2 basic leucine zipper ATF-like transcription factor 2 1 1
MIRT023329 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 1 1
MIRT023330 MAPRE1 microtubule associated protein RP/EB family member 1 1 1
MIRT023331 TBC1D22B TBC1 domain family member 22B 1 1
MIRT023332 SLC9A1 solute carrier family 9 member A1 3 3
MIRT023333 NPEPPS aminopeptidase puromycin sensitive 1 1
MIRT023334 BCL2L1 BCL2 like 1 2 1
MIRT023335 OSMR oncostatin M receptor 1 1
MIRT023336 CALU calumenin 1 1
MIRT023337 BRI3BP BRI3 binding protein 1 1
MIRT023338 PSPH phosphoserine phosphatase 1 1
MIRT023339 APMAP adipocyte plasma membrane associated protein 1 1
MIRT023340 WASF1 WAS protein family member 1 1 1
MIRT023341 LCA5 LCA5, lebercilin 1 1
MIRT023342 NODAL nodal growth differentiation factor 1 1
MIRT023343 CASP7 caspase 7 1 1
MIRT023344 CPA3 carboxypeptidase A3 1 1
MIRT023345 PALM paralemmin 1 1
MIRT023346 TCP11 t-complex 11 1 1
MIRT023347 NALCN sodium leak channel, non-selective 1 1
MIRT023348 PLAGL2 PLAG1 like zinc finger 2 1 1
MIRT023349 IDS iduronate 2-sulfatase 3 3
MIRT023350 PARP11 poly(ADP-ribose) polymerase family member 11 1 1
MIRT023351 MAZ MYC associated zinc finger protein 1 1
MIRT023352 CPNE4 copine 4 1 1
MIRT023353 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 1 1
MIRT023354 KRT14 keratin 14 1 1
MIRT023355 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1 1
MIRT023356 GNL3L G protein nucleolar 3 like 1 1
MIRT023357 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1 1
MIRT023358 EYA4 EYA transcriptional coactivator and phosphatase 4 1 1
MIRT023359 GNPDA2 glucosamine-6-phosphate deaminase 2 1 1
MIRT023360 BRCA2 BRCA2, DNA repair associated 1 1
MIRT023361 ZSCAN4 zinc finger and SCAN domain containing 4 1 1
MIRT023362 HSPA5 heat shock protein family A (Hsp70) member 5 1 1
MIRT023363 SERAC1 serine active site containing 1 1 1
MIRT023364 SLC15A2 solute carrier family 15 member 2 1 1
MIRT023365 RABIF RAB interacting factor 1 1
MIRT023366 ART3 ADP-ribosyltransferase 3 1 1
MIRT023367 EP400 E1A binding protein p400 1 1
MIRT023368 MT4 metallothionein 4 1 1
MIRT023369 TRAM2 translocation associated membrane protein 2 1 1
MIRT023370 PHPT1 phosphohistidine phosphatase 1 1 1
MIRT023371 KIAA0101 PCNA clamp associated factor 1 1
MIRT023372 VHL von Hippel-Lindau tumor suppressor 1 1
MIRT023373 IFNA1 interferon alpha 1 1 1
MIRT023374 FSTL3 follistatin like 3 1 1
MIRT023375 PHF14 PHD finger protein 14 1 1
MIRT023376 ZCCHC2 zinc finger CCHC-type containing 2 1 1
MIRT023377 GSTM3 glutathione S-transferase mu 3 1 1
MIRT023378 DCTN5 dynactin subunit 5 1 1
MIRT023379 CHST3 carbohydrate sulfotransferase 3 1 1
MIRT023380 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1 1
MIRT023381 ADO 2-aminoethanethiol dioxygenase 1 1
MIRT023382 POMZP3 POM121 and ZP3 fusion 1 1
MIRT023383 CHST12 carbohydrate sulfotransferase 12 1 1
MIRT023384 ARSB arylsulfatase B 1 1
MIRT023385 ATP7A ATPase copper transporting alpha 1 1
MIRT023386 PMP22 peripheral myelin protein 22 1 1
MIRT023387 TGFBRAP1 transforming growth factor beta receptor associated protein 1 1 1
MIRT023388 ORC2 origin recognition complex subunit 2 1 1
MIRT023389 CREB1 cAMP responsive element binding protein 1 1 1
MIRT023390 CD83 CD83 molecule 1 1
MIRT023391 TOB2 transducer of ERBB2, 2 3 5
MIRT023392 LRP11 LDL receptor related protein 11 1 1
MIRT023393 MPV17 MPV17, mitochondrial inner membrane protein 1 1
MIRT023394 TRIM29 tripartite motif containing 29 1 1
MIRT023395 OSBP2 oxysterol binding protein 2 1 1
MIRT023396 PKM pyruvate kinase, muscle 6 4
MIRT023397 FOXK2 forkhead box K2 3 3
MIRT023398 CLIC4 chloride intracellular channel 4 5 6
MIRT023399 ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1 1
MIRT023400 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1 1
MIRT023401 LMNB2 lamin B2 3 5
MIRT023402 BAX BCL2 associated X, apoptosis regulator 2 2
MIRT023403 CDK4 cyclin dependent kinase 4 3 3
MIRT054362 Cux1 cut-like homeobox 1 1 1
MIRT074336 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT109185 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT324745 ACER2 alkaline ceramidase 2 2 2
MIRT325564 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT438005 MEF2D myocyte enhancer factor 2D 1 2
MIRT438206 TGFB1 transforming growth factor beta 1 1 1
MIRT438639 AXL AXL receptor tyrosine kinase 1 1
MIRT438655 NOD2 nucleotide binding oligomerization domain containing 2 3 1
MIRT438734 FUT8 fucosyltransferase 8 3 1
MIRT449879 CYP3A5 cytochrome P450 family 3 subfamily A member 5 2 2
MIRT451716 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT453274 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT454113 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT454232 OSBPL10 oxysterol binding protein like 10 2 15
MIRT454344 CDKL1 cyclin dependent kinase like 1 2 2
MIRT455826 ZSWIM1 zinc finger SWIM-type containing 1 2 3
MIRT459903 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 12
MIRT461654 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT461934 TNFSF14 TNF superfamily member 14 2 2
MIRT463834 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT468615 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT469456 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT469637 RAD21 RAD21 cohesin complex component 2 6
MIRT473432 MDM4 MDM4, p53 regulator 2 2
MIRT473872 MAFK MAF bZIP transcription factor K 2 6
MIRT476861 FHL2 four and a half LIM domains 2 2 4
MIRT476893 FBXO21 F-box protein 21 2 2
MIRT479880 CCDC43 coiled-coil domain containing 43 2 2
MIRT488848 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT491164 LRP3 LDL receptor related protein 3 2 2
MIRT497662 PRMT3 protein arginine methyltransferase 3 2 2
MIRT499314 ZNF485 zinc finger protein 485 2 10
MIRT499759 CIRH1A UTP4, small subunit processome component 2 10
MIRT500014 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501090 SLC7A5 solute carrier family 7 member 5 2 4
MIRT509646 ZNF354B zinc finger protein 354B 2 10
MIRT509945 TOMM70A translocase of outer mitochondrial membrane 70 2 6
MIRT510320 SLC2A3 solute carrier family 2 member 3 2 4
MIRT515505 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT516410 COPA coatomer protein complex subunit alpha 2 2
MIRT517861 NCAPD2 non-SMC condensin I complex subunit D2 2 4
MIRT522558 MCAM melanoma cell adhesion molecule 2 4
MIRT523525 GLUL glutamate-ammonia ligase 2 2
MIRT523764 FBXO27 F-box protein 27 2 4
MIRT524517 CDK19 cyclin dependent kinase 19 2 2
MIRT524753 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT529366 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 2 4
MIRT531189 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT531639 C19orf52 translocase of inner mitochondrial membrane 29 2 4
MIRT531913 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT532678 PATZ1 POZ/BTB and AT hook containing zinc finger 1 2 2
MIRT533115 YIPF4 Yip1 domain family member 4 2 4
MIRT534740 RBM47 RNA binding motif protein 47 2 2
MIRT535471 PARVB parvin beta 2 4
MIRT536742 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT537237 GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2 2
MIRT539523 ABCF1 ATP binding cassette subfamily F member 1 2 4
MIRT540438 RBM43 RNA binding motif protein 43 2 2
MIRT542982 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT544674 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT549514 HDDC2 HD domain containing 2 2 2
MIRT549663 ORC6 origin recognition complex subunit 6 2 4
MIRT555420 PPIC peptidylprolyl isomerase C 2 2
MIRT564701 ZNF322P1 zinc finger protein 322 pseudogene 1 2 2
MIRT570046 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT570257 PRSS16 protease, serine 16 2 2
MIRT571143 HM13 histocompatibility minor 13 2 2
MIRT575202 Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT575282 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT575302 Osbpl10 oxysterol binding protein-like 10 2 9
MIRT575323 Fbxo6 F-box protein 6 2 2
MIRT575377 Ang angiogenin, ribonuclease, RNase A family, 5 2 3
MIRT575614 Zswim1 zinc finger SWIM-type containing 1 2 3
MIRT575671 Map1b microtubule-associated protein 1B 2 2
MIRT607065 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 2 2
MIRT607490 HEBP2 heme binding protein 2 2 2
MIRT607522 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT607655 BTN3A2 butyrophilin subfamily 3 member A2 2 2
MIRT607795 RHBDL2 rhomboid like 2 2 2
MIRT607842 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT607927 ANG angiogenin 2 3
MIRT607966 SNX22 sorting nexin 22 2 2
MIRT608074 ZFP14 ZFP14 zinc finger protein 2 2
MIRT608141 SYAP1 synapse associated protein 1 2 2
MIRT612620 RABL3 RAB, member of RAS oncogene family like 3 2 2
MIRT617444 CCS copper chaperone for superoxide dismutase 2 2
MIRT617552 MTO1 mitochondrial tRNA translation optimization 1 2 2
MIRT618772 HLA-E major histocompatibility complex, class I, E 2 2
MIRT618926 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT619247 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT620091 YME1L1 YME1 like 1 ATPase 2 2
MIRT620483 XKR6 XK related 6 2 2
MIRT620570 WBSCR27 methyltransferase like 27 2 4
MIRT622977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT623169 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT624165 DGKE diacylglycerol kinase epsilon 2 2
MIRT625268 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT625396 AKR7L aldo-keto reductase family 7 like (gene/pseudogene) 2 2
MIRT625694 OPTN optineurin 2 2
MIRT626093 MKLN1 muskelin 1 2 2
MIRT626431 CHDH choline dehydrogenase 2 2
MIRT627013 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
MIRT627077 SF3A1 splicing factor 3a subunit 1 2 2
MIRT627140 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT627347 TSHZ2 teashirt zinc finger homeobox 2 2 2
MIRT627420 THAP2 THAP domain containing 2 2 2
MIRT627441 TAS2R5 taste 2 receptor member 5 2 2
MIRT628078 KAT7 lysine acetyltransferase 7 2 4
MIRT628276 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT629094 F2RL1 F2R like trypsin receptor 1 2 2
MIRT629236 CINP cyclin dependent kinase 2 interacting protein 2 2
MIRT629286 UNC13A unc-13 homolog A 2 2
MIRT629407 ADM2 adrenomedullin 2 2 2
MIRT629584 RFC2 replication factor C subunit 2 2 2
MIRT629635 WDR31 WD repeat domain 31 2 2
MIRT629874 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT629984 NARS asparaginyl-tRNA synthetase 2 2
MIRT630043 TERF2 telomeric repeat binding factor 2 2 2
MIRT630061 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT630127 ARHGEF5 Rho guanine nucleotide exchange factor 5 2 2
MIRT630155 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT630252 SMTNL2 smoothelin like 2 2 2
MIRT630278 PSMB5 proteasome subunit beta 5 2 2
MIRT630347 NKAP NFKB activating protein 2 2
MIRT630497 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT631264 CENPM centromere protein M 2 2
MIRT631403 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT632470 RPS15A ribosomal protein S15a 2 2
MIRT632596 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT632994 DUSP18 dual specificity phosphatase 18 2 2
MIRT633082 CXorf21 chromosome X open reading frame 21 2 2
MIRT633239 ZNF573 zinc finger protein 573 2 2
MIRT633286 SLC1A5 solute carrier family 1 member 5 2 2
MIRT633536 PGBD5 piggyBac transposable element derived 5 2 2
MIRT634338 SGOL1 shugoshin 1 2 2
MIRT634600 KIAA1919 major facilitator superfamily domain containing 4B 2 2
MIRT635050 MYH11 myosin heavy chain 11 2 2
MIRT635236 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT635322 BMS1 BMS1, ribosome biogenesis factor 2 2
MIRT636268 RNF157 ring finger protein 157 2 2
MIRT636450 LRCH3 leucine rich repeats and calponin homology domain containing 3 2 2
MIRT636516 FMN1 formin 1 2 2
MIRT636755 SLC16A5 solute carrier family 16 member 5 2 2
MIRT637134 BAMBI BMP and activin membrane bound inhibitor 2 2
MIRT637188 ROMO1 reactive oxygen species modulator 1 2 2
MIRT637287 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT637532 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT637693 CEP89 centrosomal protein 89 2 2
MIRT637788 OLA1 Obg like ATPase 1 2 2
MIRT637925 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT638449 PLXDC2 plexin domain containing 2 2 2
MIRT640871 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT642643 PTGR2 prostaglandin reductase 2 2 2
MIRT643082 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643123 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT644236 SLC35E3 solute carrier family 35 member E3 2 2
MIRT644665 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT645092 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT645993 ACP6 acid phosphatase 6, lysophosphatidic 2 2
MIRT646508 FAM217B family with sequence similarity 217 member B 2 2
MIRT647013 ADCY2 adenylate cyclase 2 2 2
MIRT647095 SEC23B Sec23 homolog B, coat complex II component 2 2
MIRT647714 NFX1 nuclear transcription factor, X-box binding 1 2 4
MIRT648040 FADS6 fatty acid desaturase 6 2 2
MIRT648510 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT648865 ABCA6 ATP binding cassette subfamily A member 6 2 2
MIRT649182 DNPEP aspartyl aminopeptidase 2 2
MIRT649660 TEP1 telomerase associated protein 1 2 2
MIRT651465 XIAP X-linked inhibitor of apoptosis 2 2
MIRT652398 TMEM40 transmembrane protein 40 2 2
MIRT653691 SLC25A33 solute carrier family 25 member 33 2 2
MIRT654122 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654577 PXMP4 peroxisomal membrane protein 4 2 2
MIRT656470 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT658905 DPY19L4 dpy-19 like 4 2 2
MIRT660878 ADRBK2 G protein-coupled receptor kinase 3 2 4
MIRT661101 SPIB Spi-B transcription factor 2 2
MIRT661238 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT661291 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT662235 PGBD4 piggyBac transposable element derived 4 2 2
MIRT662544 MTAP methylthioadenosine phosphorylase 2 2
MIRT662736 LRRC3C leucine rich repeat containing 3C 2 2
MIRT662844 OMD osteomodulin 2 2
MIRT662907 MED18 mediator complex subunit 18 2 2
MIRT662956 JPH2 junctophilin 2 2 2
MIRT663340 ZNF74 zinc finger protein 74 2 2
MIRT663496 IYD iodotyrosine deiodinase 2 2
MIRT663523 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT663542 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663903 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT663973 ZNF786 zinc finger protein 786 2 2
MIRT664350 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT664417 TIGD6 tigger transposable element derived 6 2 2
MIRT664468 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT664957 PTCD3 pentatricopeptide repeat domain 3 2 2
MIRT664970 TDRD1 tudor domain containing 1 2 2
MIRT665199 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 2
MIRT665359 XKR4 XK related 4 2 2
MIRT665454 WDR17 WD repeat domain 17 2 2
MIRT665486 VPS53 VPS53, GARP complex subunit 2 2
MIRT666078 SSTR2 somatostatin receptor 2 2 2
MIRT666258 SLC31A1 solute carrier family 31 member 1 2 2
MIRT666324 SLC16A10 solute carrier family 16 member 10 2 2
MIRT666486 SBNO1 strawberry notch homolog 1 2 2
MIRT666696 RBM23 RNA binding motif protein 23 2 2
MIRT666712 RBL1 RB transcriptional corepressor like 1 2 2
MIRT666762 RAB10 RAB10, member RAS oncogene family 2 2
MIRT666931 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT667226 NFE2L1 nuclear factor, erythroid 2 like 1 2 2
MIRT667359 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT667474 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT667558 LRAT lecithin retinol acyltransferase 2 2
MIRT667748 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT668088 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT668119 GK5 glycerol kinase 5 (putative) 2 2
MIRT668166 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT668346 STXBP2 syntaxin binding protein 2 2 2
MIRT668509 ESYT2 extended synaptotagmin 2 2 2
MIRT669291 C17orf85 nuclear cap binding subunit 3 2 2
MIRT669547 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT669778 CNDP1 carnosine dipeptidase 1 2 2
MIRT669858 BROX BRO1 domain and CAAX motif containing 2 4
MIRT670017 TECPR1 tectonin beta-propeller repeat containing 1 2 2
MIRT670177 CCDC142 coiled-coil domain containing 142 2 2
MIRT671107 ZNF841 zinc finger protein 841 2 2
MIRT671351 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT671476 FLYWCH2 FLYWCH family member 2 2 2
MIRT671492 SLC38A9 solute carrier family 38 member 9 2 2
MIRT671554 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT671925 PLEKHS1 pleckstrin homology domain containing S1 2 4
MIRT672196 F2 coagulation factor II, thrombin 2 2
MIRT672217 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT672252 SIK2 salt inducible kinase 2 2 2
MIRT672290 GP2 glycoprotein 2 2 2
MIRT672430 POLR2D RNA polymerase II subunit D 2 2
MIRT672597 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT672901 KRBA2 KRAB-A domain containing 2 2 2
MIRT672958 ZNF655 zinc finger protein 655 2 2
MIRT673096 SYNPO2L synaptopodin 2 like 2 2
MIRT673171 TMEM56 transmembrane protein 56 2 2
MIRT673251 INO80 INO80 complex subunit 2 2
MIRT673296 RNF19B ring finger protein 19B 2 2
MIRT673574 KDELC2 KDEL motif containing 2 2 2
MIRT673586 KIF1C kinesin family member 1C 2 2
MIRT673737 TCF23 transcription factor 23 2 2
MIRT673767 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT674215 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674283 NAGK N-acetylglucosamine kinase 2 2
MIRT674338 KCMF1 potassium channel modulatory factor 1 2 2
MIRT674517 PRR23A proline rich 23A 2 2
MIRT675100 SNTB2 syntrophin beta 2 2 2
MIRT675144 MOGAT1 monoacylglycerol O-acyltransferase 1 2 4
MIRT675223 CLK4 CDC like kinase 4 2 2
MIRT675263 ZNF431 zinc finger protein 431 2 2
MIRT675577 WWC1 WW and C2 domain containing 1 2 2
MIRT676025 C9orf69 transmembrane protein 250 2 2
MIRT676430 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT676560 VSIG1 V-set and immunoglobulin domain containing 1 2 2
MIRT676596 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT678576 TMEM168 transmembrane protein 168 2 2
MIRT678756 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT680344 ZNF281 zinc finger protein 281 2 2
MIRT680467 C3 complement C3 2 2
MIRT682826 FLG2 filaggrin family member 2 2 2
MIRT682881 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT684404 TMEM180 major facilitator superfamily domain containing 13A 2 2
MIRT685275 KIAA1143 KIAA1143 2 2
MIRT686061 KCNA7 potassium voltage-gated channel subfamily A member 7 2 2
MIRT687526 NASP nuclear autoantigenic sperm protein 2 2
MIRT691760 BCL2L15 BCL2 like 15 2 2
MIRT693890 C3orf62 chromosome 3 open reading frame 62 2 2
MIRT699342 SLC35E1 solute carrier family 35 member E1 2 2
MIRT699909 RUNDC1 RUN domain containing 1 2 2
MIRT700536 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT701807 MRPS25 mitochondrial ribosomal protein S25 2 2
MIRT702174 LYRM4 LYR motif containing 4 2 2
MIRT706205 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT706659 RNF216 ring finger protein 216 2 2
MIRT706682 COL13A1 collagen type XIII alpha 1 chain 2 2
MIRT706705 GPR155 G protein-coupled receptor 155 2 2
MIRT706777 ANKRD36 ankyrin repeat domain 36 2 2
MIRT706844 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT706863 MAFF MAF bZIP transcription factor F 2 2
MIRT706896 ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2 2
MIRT706916 THAP6 THAP domain containing 6 2 2
MIRT706962 FANCC Fanconi anemia complementation group C 2 2
MIRT706980 XPO5 exportin 5 2 2
MIRT707015 RRP36 ribosomal RNA processing 36 2 2
MIRT707032 ACTR5 ARP5 actin related protein 5 homolog 2 2
MIRT707072 MED29 mediator complex subunit 29 2 2
MIRT709368 SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 2 2
MIRT720092 SPTLC3 serine palmitoyltransferase long chain base subunit 3 2 2
MIRT721330 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT724198 MED7 mediator complex subunit 7 2 2
MIRT725403 KIF6 kinesin family member 6 2 2
MIRT733035 COL4A2 collagen type IV alpha 2 chain 1 0
MIRT733036 COL26A1 collagen type XXVI alpha 1 chain 1 0
MIRT733426 PLK1 polo like kinase 1 3 0
MIRT734484 PLD1 phospholipase D1 3 0
MIRT736044 CBL Cbl proto-oncogene 3 0
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