miRTarBase - #MIRT191454 -
pre-miRNA Information
pre-miRNA hsa-mir-15a   
Genomic Coordinates chr13: 50049119 - 50049201
Synonyms MIRN15A, hsa-mir-15a, miRNA15A, MIR15A
Description Homo sapiens miR-15a stem-loop
Comment Reference .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-15a-5p
Sequence 14| UAGCAGCACAUAAUGGUUUGUG |35
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1355089203 8 dbSNP
rs753467375 11 dbSNP
rs923737993 12 dbSNP
rs766120172 20 dbSNP
rs1359939022 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PPM1A   
Synonyms PP2C-ALPHA, PP2CA, PP2Calpha
Description protein phosphatase, Mg2+/Mn2+ dependent 1A
Transcript NM_021003   
Other Transcripts NM_177951 , NM_177952   
Expression
Putative miRNA Targets on PPM1A
3'UTR of PPM1A
(miRNA target sites are highlighted)		 
>PPM1A|NM_021003|3'UTR
   1 AACTGCTCATCTAGCCATGGAGTTTACCTTCACCTCCAAAGGAGAGTACAGCTCAACTTTGTTGAAACTTTTAACATCCA
  81 TCCTCAACTTTAAGGAAGGGGATATGACATGGGTGAGAATGATTACATCAGAGAACTTCAGCAGTACAACAGCTAGCCCA
 161 GAACTGATTTTTTTTTTTTTTTTTGTAAATTTGAGACTTATGTAAGCGTGATTTCAAACCATAATTCGTGTTGTAAATCA
 241 GACTCCAGCAATTTTTGTTGTATGATTTTGTTTTTTTGTAAAGTGTAATTGTCCTTGTACAAAATGCTCATATTTAATTA
 321 TGAACTGCTTTAAATCACTATCAAAGTTACAAGAAATGTTTGGCTTATTGTGTGATGCAACAGATATATAGCCCTTTCAA
 401 GTCATGTTGTGTTTGGACTTGGGGTTGGAACAGGGAGAGCAGCAGCCATGTCAGCTACACGCTCAAATGTGCAGATGATT
 481 ATGGAAAATAACCTCAAAATCTTACAAAGCTGAACATCCAAGGAGTTATTGAAAACTATCTTAAATGTTCTTGGTAGGGG
 561 AGTTGGCATTGTTGATAAAGCCAGTCCCTTCATTTAACTGTCTTTCAGGATGTTCCTTCGTTGTTTCCATGAGTATTGCA
 641 GGTAATAATACAGTGTATTCATAAGAATCTCAATCTTGGGGCTAAATGCCTTGTTTCTTTGCACCTCTTTTCAAGTCCTT
 721 ACATTTAATTACTAATTGATAAGCAGCAGCTTCCTACATATAGTAGGAAACTGCCACATTTTTGCTATCATGATTGGCTG
 801 GGCCTGCTGCTGTTCCTAGTAAGATATTCTGAATTCCATTTTATCAATAAAGCTTGATTTAACAAACAAGAAACTTAATC
 881 ATGTATGTGTAATTCCTCTTTTACCCTGGCCTTTTAAAACACTGTGCCGTTGTAATGAGACGTTTCTCATAGGGAAAGAT
 961 GTTAGTCTCTTTTAATTGGACAACACTGTCACTCAAGGCATAGATGAAACTTTCCTTCCATTAGAAAGACTAAAAGATTT
1041 AATTCTTGGTTGTACCTTAATCTATTTTTTAAATAGGTTTCTTTCAGGCTGCTTATTTTTCATTAAGATGTGTATCAGCT
1121 TGGATTTGCCTACTGTTTAATTAAAATATTTATTGTCAAAGTTTGACAATCTAACACTCTATGGTAGGGGTGTGTGTGTG
1201 TGTGTTTGTGAGTGTGTGTTTGCCTGTGATTTTTAATTGGCCCATGTCTTTAGAATCCAAGTGGTTAAGATGTATTTGTG
1281 ATTTGAAATATAGCATGTTGATAATATTTAGCTGTTGGCCTTTACAAATAACTTTCAAAGCTTAAGGAATTGTAGATATA
1361 AAAATAACCTAATTTAATTTAGGCTTAAATTCCTCTGATTAAGCATGTGAAAGTAAGTTTTAAAATCTGTCGCATTGAAA
1441 AGATTACTGTTCCGTGCCCTTCTGTATTTTTGTCTCTTTAGGTTGAATATTGTATTTATCACCATGTAATCATTCAGTAG
1521 GCAGATTCCCACTAGAAAACTGTTGAAATGTAAGACTAAAATACAACATTGAATACAAAATCAAAATTTTGTGTATAAAA
1601 ACCAGTATAGTCCATTTTGTTATATTTGTTTTTTCCCTAACTTGGAAATATACATATTTGTATATATAGCCTTAAAATTA
1681 ATGTAAAGTTAGGGGAGTAGTGGGGAAAGTAATGTGAAATGTCTCAGATTTAAGTAGTTAAATACCAGCAAAATCTTTTC
1761 ATTATCCCTCTTATTTTGTGAGGTGATTAAATGTAACTTAATTGTATTTAATTTATATCTTATTCCAGCATGAATGAGGA
1841 AAAACTGAAGTACTATTTATATTTAGAAATTCATATCAGTTGAAATTACAGAACCAATTCCATACTTACAATAAATACTT
1921 AATGTCTAAATCTGTGGTAGAGTGCGAAGTATGATAATGTTCTAAGTTATGGCTTTGCAAGCATCTAAATGTGCATTTAA
2001 TGAATACCAGTGCTTCTAGTATAGACTAATTACCAGACATACTGGTACTGAAAGCTAAATCCCTATTATAACAAACCAGT
2081 TCCTTAATATTTTAAGTAGACTGACAACTTTAGTTCCAGAAATTGCAAAACTTTGAACTGGACTGTGTAATCTTTTGAGA
2161 TGCAAAACTTAAGTCACAAGTAGAGTATGTGATGGAAAGCTGTATTTCAAACCATAACAGCATATTTAGAGCCTTTTTTT
2241 TTTGAGTCTTTAAACAAGAGAAAATTAAAATATTCCTGTCAAAATTATTAGTATTGAAATTAGGCTTGGACACGAGAGAG
2321 AACCGTATTTGAGTGATGTGAGAAGACTAAATCTTTTCCACATGAGTCAGCACTGCCATACTAATAATTTTTTTACTATA
2401 AAAATACAGGAAGGAAGTATACATTATAACAGCAGACTGTGTGTGTTCCTGATTCCTGGAGGTAATAGTGGGGGGAAACC
2481 AACCATACTTTTTAAAGGCACTTTTGCACCTCTATTGTGCACTTCATTCTTGTACCACTTAAATTCTTCACCCCCATCCC
2561 CTTTTTTTGTGCTAATTAGCATCTCAGGGCAATGCCTCAAAAATGTTTGATGTGTTCTGTTCTTTGGAGGGAAAAAGTTC
2641 TTATGTGATGATAATATAGTACTCAAAATATACTTTTATCATTTAAATGTCTTATTTGCTGCTATGAATAGGAAATAACA
2721 TTTTGTATAGCAGGCTCTGTTTTACCCTAACATTAAAAAATTTCACTGATCTTTCTTTCATTAACAGGGTAGAATCTCCT
2801 AATTTCCACTTTCTTGGGAATATACTTTTATAGACAATAGAAGCAGTTCTCAATATTAGCATATACTTTAAAAAATCAAA
2881 GTGATAACTTAATTCAGCTTTGGAAGTATCTCAAACATATTTTTACTTTATAGTGCATTAACTTGCTTCTAGAGTACTTA
2961 ATGCAACTGCTCTAGCCACTTAATTTTTTATACTAATCTCAACATTAAGAAATTTGGATTAAGTAATAAATTAGTTATGT
3041 AATTCAAGTAATCTGAATTACAGCAGTACTTTTAGTGATCATTCATAGGACTATATATTAACCCAGCTAATAACTCAGTT
3121 TTTTTACAAAATGTTTCGAGTATTATTGGTAAAACACTGTTCTAGGCTAAGCACATTGGGACTGTAAAGAAATGAGTAGA
3201 TCCTTGGCTTCAAGTTTACATCTGGACAATTTATAATCTAGTGTATGTTAGTATTATAACTGGATCACTCATCAAAAAAT
3281 ATATATATATATCTATTGCCCACCTGCTATCTACCAGGTACTTAGCTGATCAAGGCAGGCCCCTGCCCTAAAGACCTTGT
3361 TTATACTTCCTTTACTCACCTGAAAACTGTTCTCCAGTTTATTTTCTTCTCTCTAAAGTTAAAGAGTAATTCAGAAGAAA
3441 ATTTTGCTTAGCATAAGAATAAAATTGGACTGAAGAGGCTTAAGCCCATTCAGTATCCTTGATTGCATTTATCCAACGGC
3521 CTTTATTCTTCCTGCTGACAGCAGTAACTCAGAGGAATAGGTAGTAGATTTCTGAAAATTATCCAGCCATGGAAATGTAG
3601 GTGGGGTTTGAGTTTAAGGCATTTAAAAATGTAAATATCTCTAGCTAAATTTATCTTAAGTAGAACTCTGTGTTTTTGTA
3681 ACACACTGCCAGTGTTAATATCAAATTTTAGCCAAATTATTACTATGTGTTTTAATATTTTAAAATAATTTCACTGCCCA
3761 TCTTTACTGGACAAACTCATTTGGAGTTCAACTTGTGATTTCTGAAAGAACTGATGAAATTGGGTACTGCTTTTTTTCTC
3841 CATTTTTCGTTTTGTTTTAATTTTGAATTTCATGGTATATACTTTTAGTTCAAACTCAGCTGTTTGTACAGTATTGTATT
3921 AGGATTTGGTATTAGAAAAGATGTGTAAATATCTTAGTATATAATTGTTTCTCATTTGAGGTTTTTCTTCTAAGGGACCT
4001 TAAAGAGTTTTATATACTTTTGCTCACAGAAACTGCTGGTGAGATTACCATTTTTTGAGTATCTAGTCTTCTAGTTTTTC
4081 TTTTAGGCATTAGGAAGCCTTCTTTAGAGTTCAAAATTTTAGAAGCCTAATTTGCTCTTACTTCCTTCAATTATGTGCCA
4161 TGTGTTTTGGTTTGTATATGTTTTAAATTGTATATTTCCTTGGAATATGCTTGAAATATTTAAGAATACATTTTCAAAAT
4241 GTATAATACTGTATTGTTTTGTTGATCAGAATAATAAGTCTCAGTTAAATGTTTGTTATTACTGATAGTCAAAATGCTCA
4321 ATAGAAATGATGAGAGGCATTGGTTCCAATTCATTGTCAAATGAACGTTTTCTAATTTTGTTCACAGATTCTTTCCCTTT
4401 CGATTGTTCTGTATGTTAAGATAGTGGCTTCTGCTCTCACTGTTTTCCTATTTATATTACTAGCAGGTAGGAGTGCTAAT
4481 TAGAAAAACTTAGATGGTATTGAAATTACAGTTGACAACTTATATTTTTATGAGATGGAGAAAAAAGATTAAGTTGATAT
4561 AACAACAAAGTGGACTTTTTTTCTTCCTTATCCTGCACGAAATATTGCCCTTGTTTCCTCTACTTTCCTCTTGGTGTTTT
4641 CTCTTTTTTTCAAACAGAAACAGGCCAATTCCATTTTCTTGAGCAAGAAAGCTTAGTGTGTTACTTCATCAAGGCCAGCT
4721 AATACTGTGTTAAACCGGGCTGAAAATGAGAAAACTTGGGAGATGGAGGAATGGGGAAATGGCAGTGGGATAGGTAGGGA
4801 AGGATTACTCTTAATTGTTTTAAAAGCCATAGGAAAGTCTTCCTTGTACGTGGCTGTAAATTTATAAGAACTATTGTGTC
4881 ACATAAACCAACAAGAATGAACCTTTGCTGCTTCAGATAATTTGATTTTTCCAGCAAGGAAATTAATAAGTTACTGATTC
4961 TTCAGCATAGAAACAACTGAGAAGAATTAATGCAATGTTTCTTCACTAGAAAACCCAACCCTTCATTTCTTTTCATTGCT
5041 CCAAAACCCAGTTTTCAACTAATGGTTTTCTCATTAAACTAAATGTTTAGAAAAGTTGTTTAGAGTTTTTCTTTTTCTTT
5121 TACATAGTCCTCCTGATCCAGTATAAGACTATTTAGTAACGTGCATTTGTATGGTACTATCTAAAGTAAGTTAGATTGAT
5201 GTAAGAGATCGGGTAGCTGCGGAACAAAATTAGTTATATCCTAATTAGGTACAGTGAATGACACAAAATCATTTTAGCAA
5281 TGCTTCTTAACCTTTTGGGGTCACAGGCGTTTTGAGACTGATGAATCCTAGGGACTTATTTACCCAGGAAAATGCGTATA
5361 TAACATACATATCTCCCTAAAGTTTACAATATTGTAGTGGTTCATGGGCCCCCTGGTTAAGAGCCCATTCTAAAGTACAA
5441 TAGGGCATCATCCCTTTTCCTGCAAAGCCCAAAAGTATATTTCTAGGGCATGAAAATAACTTGAGTCTATTTTAAGGAAT
5521 TGTTTCACTCTAGAGGTAGATAGGGGACCTGGCTAGAATCTGACATTAAAATATACTTTTTAAAAAATATTATATTTGGG
5601 GTGGGGAAAGTGATTAAAAGGTGAAAAAAAAACATAGTATTCAGAAGTTTTGGAGGTTAATGTCTTTCTCTAAGATTTGC
5681 CACTTTAGAAATTCAACAGAAAAGAGGTAAAACAGAAATGGAATGTATCTGGAACATTTTTGGCCTCCATAGTGCAGATA
5761 TACTATATTAACAAGTAATACATTTATTTACCTGTCAGATCTCCAGGTTTTAAGATTTTGAGCTTTCTAGTATTAGGATT
5841 CATTAAATGTTCAATTCATTTCATATTCTAAGGAATTAGGTTATTTACTTACTAATTCAGGATGTTAAAATAACATCCAA
5921 GTCGGACAACCACCACCAATGCACACAGTTAATGAGATTTCTAAAATATAATAAGTACAATGTAACAAACGTATAGAATT
6001 TTGCATTTGTTGCCAAAATTAGATGTTTAATGACAGCTTATTTAATTCCCATTTGTGGGACTTCTGGAACATAGAAACCA
6081 TTATCTTACCTGGTTATCCCTTGACTAAATAGCATATCTGCAGGAAAATATCTTGTTTGTAGTGATATGCCCCAATAGTG
6161 ATTGATTTCACTCTTGAAATGAGTTATATCACTTAATTTGTATAAATGTTATGAGTGGAGAGACATGTACATGTTAAAAG
6241 CATGTTGCATTATATATTCATTTTTTAAACTCTATAAATGTTAAGAATAATATAATTGCAGAAATATTTTTCTTAAATAC
6321 AATGTGTAACAAAATTCTCCGTAGCAACTCACCCACTTTGCAGTTTATGTGATCCACACTTTTAAAGAAATTCCATAAAT
6401 GTATATTTTGTATTATGTATTATTTCCTGGTCCAAAGAAAATATGTGAATTCAGTTCTAACTTTAAGAATGTACTGTTTG
6481 TTTTCAAGTTCATTGAAAAATTGCATTCAGCCTGCGAATGGTTGCAGATTGTATGTTAGATGAAAAGTAGAAATAATTTC
6561 TAGTTTGGAAAACTGGTGCCACTAAATAAACAGGCAATTACATAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1 
miRNA  3' guGUUUG-GUAAUACACGACGAu 5'
            :|||: : |||| ||||||| 
Target 5' ttTAAATGTCTTATTTGCTGCTa 3'
 		2682 - 2704 164.00 -12.60
2 
miRNA  3' guGUUUGGUAAUACACGACGAu 5'
            ::|||| ||   ||||||| 
Target 5' aaTGAACC-TT---TGCTGCTt 3'
 		4896 - 4913 152.00 -11.60
3 
miRNA  3' guguuUGGUAAU--AC----ACGACGAu 5'
               |: |||:  ||    ||||||| 
Target 5' ctatcATGATTGGCTGGGCCTGCTGCTg 3'
 		785 - 812 145.00 -13.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31505535 17 COSMIC
COSN30183620 21 COSMIC
COSN31482540 52 COSMIC
COSN31576245 77 COSMIC
COSN24377703 116 COSMIC
COSN27513958 185 COSMIC
COSN29045239 185 COSMIC
COSN29096329 185 COSMIC
COSN17037870 308 COSMIC
COSN17182118 424 COSMIC
COSN25486808 596 COSMIC
COSN15032007 641 COSMIC
COSN9616340 813 COSMIC
COSN16113530 1107 COSMIC
COSN27992234 1205 COSMIC
COSN9088966 1414 COSMIC
COSN16716453 2134 COSMIC
COSN20111362 3126 COSMIC
COSN24959861 3419 COSMIC
COSN27956399 3838 COSMIC
COSN19491087 3880 COSMIC
COSN23079453 3933 COSMIC
COSN26754970 4004 COSMIC
COSN31539188 4145 COSMIC
COSN31533056 4148 COSMIC
COSN1655736 4227 COSMIC
COSN19118900 4432 COSMIC
COSN17681529 4620 COSMIC
COSN21467797 4711 COSMIC
COSN17272957 5020 COSMIC
COSN9616341 5371 COSMIC
COSN31779047 5477 COSMIC
COSN26422118 5583 COSMIC
COSN27332730 5633 COSMIC
COSN29881263 5657 COSMIC
COSN20092846 6067 COSMIC
COSN19136070 6088 COSMIC
COSN31779031 6516 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs762697559 4 dbSNP
rs1341123938 8 dbSNP
rs917524222 9 dbSNP
rs988464360 12 dbSNP
rs765879902 18 dbSNP
rs775843782 19 dbSNP
rs1044591851 23 dbSNP
rs761013328 29 dbSNP
rs909619087 32 dbSNP
rs1351975818 35 dbSNP
rs1437461988 37 dbSNP
rs1203587985 38 dbSNP
rs764627539 40 dbSNP
rs182653798 45 dbSNP
rs757656654 46 dbSNP
rs765390281 47 dbSNP
rs750406687 48 dbSNP
rs943631746 50 dbSNP
rs758662067 52 dbSNP
rs1435302023 58 dbSNP
rs1268972821 60 dbSNP
rs1036748432 63 dbSNP
rs1039264658 64 dbSNP
rs896785222 72 dbSNP
rs1343425782 74 dbSNP
rs1202581721 76 dbSNP
rs899392837 84 dbSNP
rs1318430160 86 dbSNP
rs1453159125 98 dbSNP
rs1279834435 102 dbSNP
rs930672751 107 dbSNP
rs1482922762 110 dbSNP
rs529389931 114 dbSNP
rs1014251336 117 dbSNP
rs886564788 117 dbSNP
rs1473289662 128 dbSNP
rs1181830102 140 dbSNP
rs1050939103 146 dbSNP
rs1024099038 149 dbSNP
rs1405932126 168 dbSNP
rs1418149599 168 dbSNP
rs201235752 168 dbSNP
rs745766481 168 dbSNP
rs78082039 168 dbSNP
rs905665540 183 dbSNP
rs75651391 184 dbSNP
rs374426865 185 dbSNP
rs889736291 185 dbSNP
rs201408914 186 dbSNP
rs1402717031 188 dbSNP
rs1428862663 189 dbSNP
rs1306409587 194 dbSNP
rs1372574410 195 dbSNP
rs1484225939 198 dbSNP
rs1256362941 200 dbSNP
rs549564152 202 dbSNP
rs957510667 208 dbSNP
rs988518129 209 dbSNP
rs1007119249 216 dbSNP
rs1022169318 228 dbSNP
rs762437388 229 dbSNP
rs569479910 234 dbSNP
rs1296098475 241 dbSNP
rs1313072847 245 dbSNP
rs112135102 246 dbSNP
rs1403629507 249 dbSNP
rs1288589534 263 dbSNP
rs986520610 267 dbSNP
rs1358187301 278 dbSNP
rs912065984 283 dbSNP
rs750881680 286 dbSNP
rs956000898 289 dbSNP
rs1439969055 291 dbSNP
rs1341984675 292 dbSNP
rs574409878 295 dbSNP
rs1184861589 296 dbSNP
rs1441164795 298 dbSNP
rs1256792915 303 dbSNP
rs992842296 304 dbSNP
rs1204276107 314 dbSNP
rs191759856 331 dbSNP
rs570340866 338 dbSNP
rs1483804922 339 dbSNP
rs1195906212 341 dbSNP
rs766675296 342 dbSNP
rs975302583 351 dbSNP
rs1247097120 359 dbSNP
rs980668043 364 dbSNP
rs1449361520 367 dbSNP
rs539455661 369 dbSNP
rs1200995164 373 dbSNP
rs777087885 382 dbSNP
rs941527791 388 dbSNP
rs11848262 389 dbSNP
rs1299250452 391 dbSNP
rs918347102 406 dbSNP
rs543023439 408 dbSNP
rs933643820 410 dbSNP
rs1364575917 417 dbSNP
rs1166425841 419 dbSNP
rs1392286271 422 dbSNP
rs1368942523 435 dbSNP
rs886406026 440 dbSNP
rs950149400 449 dbSNP
rs1293138616 452 dbSNP
rs1490229943 455 dbSNP
rs1388743740 461 dbSNP
rs1265554058 462 dbSNP
rs572869860 464 dbSNP
rs1250875459 473 dbSNP
rs1324787339 475 dbSNP
rs1365036483 477 dbSNP
rs535192748 481 dbSNP
rs1001411225 485 dbSNP
rs1330097455 487 dbSNP
rs1300224498 490 dbSNP
rs1388193462 493 dbSNP
rs942669781 503 dbSNP
rs1368478667 505 dbSNP
rs1054694946 508 dbSNP
rs893063840 511 dbSNP
rs1463997022 514 dbSNP
rs1425700626 519 dbSNP
rs1171059326 526 dbSNP
rs1048318 528 dbSNP
rs1353645900 530 dbSNP
rs1201248664 539 dbSNP
rs1296148174 556 dbSNP
rs575100154 564 dbSNP
rs1253571051 569 dbSNP
rs1464355884 576 dbSNP
rs1186560285 577 dbSNP
rs1249711613 588 dbSNP
rs184045698 592 dbSNP
rs1007881397 599 dbSNP
rs1223237039 603 dbSNP
rs1366869866 607 dbSNP
rs1018050717 610 dbSNP
rs564081941 620 dbSNP
rs577935834 621 dbSNP
rs1330015068 624 dbSNP
rs920721539 627 dbSNP
rs1388594501 629 dbSNP
rs377351543 636 dbSNP
rs1331997972 645 dbSNP
rs1413884469 648 dbSNP
rs1422781719 651 dbSNP
rs952303597 656 dbSNP
rs116388200 668 dbSNP
rs1014260838 670 dbSNP
rs907898483 674 dbSNP
rs1441656321 685 dbSNP
rs1363173249 698 dbSNP
rs1203565743 703 dbSNP
rs188931057 705 dbSNP
rs1046139307 718 dbSNP
rs1024342249 723 dbSNP
rs927442522 725 dbSNP
rs1395739176 733 dbSNP
rs144489291 735 dbSNP
rs1237277850 738 dbSNP
rs868473469 742 dbSNP
rs1338285969 750 dbSNP
rs1054305591 759 dbSNP
rs980340299 761 dbSNP
rs1017621339 763 dbSNP
rs962879350 771 dbSNP
rs1357359838 776 dbSNP
rs137960964 777 dbSNP
rs1414846910 779 dbSNP
rs1041681282 798 dbSNP
rs918315842 800 dbSNP
rs764323151 810 dbSNP
rs1441827917 813 dbSNP
rs112358642 823 dbSNP
rs1007927611 827 dbSNP
rs1048359 830 dbSNP
rs986423372 837 dbSNP
rs1183139106 845 dbSNP
rs910857408 848 dbSNP
rs963831113 854 dbSNP
rs1269939264 861 dbSNP
rs942365556 869 dbSNP
rs563067655 876 dbSNP
rs142140579 881 dbSNP
rs1355488288 884 dbSNP
rs376146900 896 dbSNP
rs1286019928 897 dbSNP
rs757970423 899 dbSNP
rs1376823446 904 dbSNP
rs983563718 906 dbSNP
rs748021063 908 dbSNP
rs1425744639 911 dbSNP
rs765861195 923 dbSNP
rs1411394521 925 dbSNP
rs756049726 929 dbSNP
rs1421749597 934 dbSNP
rs1162003191 936 dbSNP
rs1346244907 941 dbSNP
rs1164102409 942 dbSNP
rs891877606 943 dbSNP
rs1416541542 952 dbSNP
rs1014313102 957 dbSNP
rs1164314504 958 dbSNP
rs115257358 965 dbSNP
rs1381755884 969 dbSNP
rs1261469464 970 dbSNP
rs905840126 970 dbSNP
rs1196299821 974 dbSNP
rs139706576 991 dbSNP
rs1489032139 991 dbSNP
rs192420039 1006 dbSNP
rs1054926166 1013 dbSNP
rs777541506 1015 dbSNP
rs531824211 1016 dbSNP
rs1291464791 1021 dbSNP
rs914644130 1024 dbSNP
rs546544905 1031 dbSNP
rs1041563578 1039 dbSNP
rs1341310293 1043 dbSNP
rs144474881 1046 dbSNP
rs1209206530 1049 dbSNP
rs891086154 1053 dbSNP
rs545219024 1054 dbSNP
rs1465498780 1057 dbSNP
rs1422123437 1061 dbSNP
rs1254072196 1065 dbSNP
rs1478370351 1069 dbSNP
rs955548479 1079 dbSNP
rs1190248479 1082 dbSNP
rs182064708 1089 dbSNP
rs200827201 1096 dbSNP
rs535132362 1097 dbSNP
rs1213775667 1105 dbSNP
rs1039377317 1113 dbSNP
rs963717854 1115 dbSNP
rs1220199255 1118 dbSNP
rs979537235 1120 dbSNP
rs925206560 1130 dbSNP
rs1026714199 1136 dbSNP
rs1370002253 1139 dbSNP
rs935268897 1143 dbSNP
rs1294125440 1154 dbSNP
rs770597574 1158 dbSNP
rs1398684846 1170 dbSNP
rs1333915784 1173 dbSNP
rs1466646581 1177 dbSNP
rs917717461 1185 dbSNP
rs568537913 1186 dbSNP
rs565383124 1188 dbSNP
rs1005047752 1190 dbSNP
rs147304544 1190 dbSNP
rs949218091 1192 dbSNP
rs971681656 1201 dbSNP
rs778473122 1202 dbSNP
rs555091847 1203 dbSNP
rs1200435713 1204 dbSNP
rs1313118494 1207 dbSNP
rs1034375348 1212 dbSNP
rs745568163 1216 dbSNP
rs958984620 1225 dbSNP
rs186615079 1233 dbSNP
rs1407480147 1249 dbSNP
rs1299350306 1256 dbSNP
rs1373394557 1257 dbSNP
rs537676660 1258 dbSNP
rs1311629921 1262 dbSNP
rs191864416 1265 dbSNP
rs1402124049 1279 dbSNP
rs1301402025 1285 dbSNP
rs1467922875 1289 dbSNP
rs867146133 1292 dbSNP
rs183895114 1293 dbSNP
rs1173845479 1296 dbSNP
rs1234674108 1304 dbSNP
rs1418765390 1308 dbSNP
rs1274214680 1322 dbSNP
rs946109791 1326 dbSNP
rs527459483 1328 dbSNP
rs1419538333 1337 dbSNP
rs775157978 1343 dbSNP
rs955517762 1351 dbSNP
rs1179859294 1353 dbSNP
rs1233572792 1354 dbSNP
rs912363590 1358 dbSNP
rs1216146460 1370 dbSNP
rs1351864348 1378 dbSNP
rs12894934 1383 dbSNP
rs1008825292 1386 dbSNP
rs943983293 1390 dbSNP
rs1239877384 1393 dbSNP
rs1018011137 1395 dbSNP
rs1040003828 1404 dbSNP
rs1311249115 1405 dbSNP
rs1398349105 1406 dbSNP
rs1380324656 1418 dbSNP
rs1190045736 1422 dbSNP
rs190120916 1429 dbSNP
rs979119318 1432 dbSNP
rs924905382 1433 dbSNP
rs931000967 1449 dbSNP
rs1389201455 1453 dbSNP
rs1427473131 1454 dbSNP
rs762400966 1455 dbSNP
rs1257960135 1457 dbSNP
rs1048047984 1459 dbSNP
rs1487398347 1468 dbSNP
rs988032474 1473 dbSNP
rs1265642252 1482 dbSNP
rs917853213 1484 dbSNP
rs1354672938 1489 dbSNP
rs1355693206 1490 dbSNP
rs575356027 1492 dbSNP
rs1247614345 1497 dbSNP
rs1336205591 1498 dbSNP
rs1277893577 1499 dbSNP
rs981034416 1501 dbSNP
rs1003884808 1502 dbSNP
rs193041271 1506 dbSNP
rs1291727595 1508 dbSNP
rs937457666 1514 dbSNP
rs1038464154 1517 dbSNP
rs1441402420 1518 dbSNP
rs1951118 1519 dbSNP
rs185637907 1528 dbSNP
rs1291350817 1529 dbSNP
rs531921329 1530 dbSNP
rs1459318126 1531 dbSNP
rs930000107 1539 dbSNP
rs190448443 1544 dbSNP
rs1476736826 1552 dbSNP
rs1425560006 1554 dbSNP
rs1194144419 1557 dbSNP
rs1216605066 1559 dbSNP
rs1273967523 1562 dbSNP
rs1211723270 1563 dbSNP
rs74951857 1564 dbSNP
rs1258011310 1567 dbSNP
rs180910551 1569 dbSNP
rs1320419604 1570 dbSNP
rs547210636 1583 dbSNP
rs185478645 1589 dbSNP
rs1469273366 1592 dbSNP
rs1227697182 1609 dbSNP
rs967460982 1612 dbSNP
rs1018898898 1614 dbSNP
rs1442492593 1634 dbSNP
rs1395078255 1635 dbSNP
rs900004727 1636 dbSNP
rs1000984035 1645 dbSNP
rs1032111727 1646 dbSNP
rs1168353790 1652 dbSNP
rs73317863 1659 dbSNP
rs1376149141 1663 dbSNP
rs975259722 1665 dbSNP
rs921213645 1667 dbSNP
rs567199837 1669 dbSNP
rs528897808 1670 dbSNP
rs1404263544 1671 dbSNP
rs1197285665 1675 dbSNP
rs1162040155 1684 dbSNP
rs1395989170 1686 dbSNP
rs1024877545 1689 dbSNP
rs1274071664 1699 dbSNP
rs1200252805 1704 dbSNP
rs548654793 1722 dbSNP
rs1343790515 1723 dbSNP
rs188277841 1725 dbSNP
rs971090339 1726 dbSNP
rs1236094669 1752 dbSNP
rs1371066854 1756 dbSNP
rs1461940231 1762 dbSNP
rs529186168 1768 dbSNP
rs1362847400 1778 dbSNP
rs1432554505 1783 dbSNP
rs1329234408 1797 dbSNP
rs1271006018 1799 dbSNP
rs1413725700 1802 dbSNP
rs1378660609 1820 dbSNP
rs1399843204 1823 dbSNP
rs1226713350 1828 dbSNP
rs1175731054 1830 dbSNP
rs1275170259 1831 dbSNP
rs1335528638 1840 dbSNP
rs1208718475 1846 dbSNP
rs908189968 1848 dbSNP
rs926417239 1850 dbSNP
rs1176860678 1853 dbSNP
rs1442024611 1854 dbSNP
rs939792706 1856 dbSNP
rs568581699 1862 dbSNP
rs373046176 1865 dbSNP
rs1003489133 1867 dbSNP
rs1212564761 1870 dbSNP
rs73317864 1874 dbSNP
rs529970032 1876 dbSNP
rs1021646348 1883 dbSNP
rs766796384 1889 dbSNP
rs1047076379 1892 dbSNP
rs1280032992 1894 dbSNP
rs967348460 1900 dbSNP
rs1338469148 1906 dbSNP
rs891376614 1910 dbSNP
rs1360197520 1912 dbSNP
rs944323113 1915 dbSNP
rs1020146054 1916 dbSNP
rs1402566121 1919 dbSNP
rs1408845134 1923 dbSNP
rs73317865 1925 dbSNP
rs1472102998 1926 dbSNP
rs1239507222 1929 dbSNP
rs1205297366 1931 dbSNP
rs1189172268 1933 dbSNP
rs1485784765 1935 dbSNP
rs139684382 1936 dbSNP
rs921073251 1944 dbSNP
rs1001053455 1946 dbSNP
rs983979301 1947 dbSNP
rs1227611319 1954 dbSNP
rs1354245670 1958 dbSNP
rs1386293581 1971 dbSNP
rs1032081899 1974 dbSNP
rs892241394 1981 dbSNP
rs1340085446 1982 dbSNP
rs1296539939 1989 dbSNP
rs11620995 1992 dbSNP
rs1046040342 2020 dbSNP
rs1024678838 2022 dbSNP
rs927744394 2023 dbSNP
rs937735243 2025 dbSNP
rs1056372999 2033 dbSNP
rs894612060 2034 dbSNP
rs1421966162 2036 dbSNP
rs1184350014 2037 dbSNP
rs1486646910 2038 dbSNP
rs970426377 2048 dbSNP
rs1220264968 2055 dbSNP
rs1358329881 2069 dbSNP
rs574065050 2070 dbSNP
rs1449774258 2077 dbSNP
rs1295339700 2078 dbSNP
rs981059060 2079 dbSNP
rs1356253872 2082 dbSNP
rs1227793622 2083 dbSNP
rs1317019601 2089 dbSNP
rs1011851360 2097 dbSNP
rs1216478879 2099 dbSNP
rs1287024278 2109 dbSNP
rs1033621737 2116 dbSNP
rs1274317904 2120 dbSNP
rs751681731 2125 dbSNP
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rs1398477682 2153 dbSNP
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rs916975453 5050 dbSNP
rs1272403500 5060 dbSNP
rs548255260 5062 dbSNP
rs949610244 5076 dbSNP
rs746269806 5083 dbSNP
rs34064379 5099 dbSNP
rs568186968 5102 dbSNP
rs984848464 5106 dbSNP
rs537161857 5108 dbSNP
rs1345367759 5116 dbSNP
rs772258484 5125 dbSNP
rs1267339636 5126 dbSNP
rs1331551021 5128 dbSNP
rs905445713 5128 dbSNP
rs1036994762 5131 dbSNP
rs1267746380 5145 dbSNP
rs557093278 5155 dbSNP
rs1447333255 5157 dbSNP
rs1338790987 5159 dbSNP
rs190403165 5160 dbSNP
rs150309578 5161 dbSNP
rs889293434 5162 dbSNP
rs1011288984 5175 dbSNP
rs1042844283 5179 dbSNP
rs1413665184 5182 dbSNP
rs553669911 5182 dbSNP
rs571934146 5184 dbSNP
rs1416301147 5190 dbSNP
rs1951112 5193 dbSNP
rs1463381439 5194 dbSNP
rs1235243366 5201 dbSNP
rs1951113 5204 dbSNP
rs1030444791 5209 dbSNP
rs998560821 5211 dbSNP
rs1007350566 5212 dbSNP
rs1035997092 5222 dbSNP
rs1466111822 5228 dbSNP
rs960021782 5230 dbSNP
rs1017358937 5232 dbSNP
rs1227965282 5237 dbSNP
rs1354330585 5241 dbSNP
rs1286087748 5245 dbSNP
rs1246141713 5246 dbSNP
rs1381312302 5250 dbSNP
rs1365158523 5252 dbSNP
rs1013158362 5265 dbSNP
rs963278647 5266 dbSNP
rs1437668268 5272 dbSNP
rs1327746776 5282 dbSNP
rs1318489467 5283 dbSNP
rs1404465377 5286 dbSNP
rs1218691982 5288 dbSNP
rs1022720824 5300 dbSNP
rs561139533 5310 dbSNP
rs1445134213 5315 dbSNP
rs952550389 5326 dbSNP
rs1389436636 5331 dbSNP
rs1186619519 5334 dbSNP
rs1292645056 5340 dbSNP
rs973272405 5346 dbSNP
rs529933804 5356 dbSNP
rs909316560 5357 dbSNP
rs1235012566 5358 dbSNP
rs1265827108 5369 dbSNP
rs764009662 5370 dbSNP
rs868467316 5372 dbSNP
rs992898272 5389 dbSNP
rs1231258627 5394 dbSNP
rs1366367513 5395 dbSNP
rs541057702 5401 dbSNP
rs1274689438 5406 dbSNP
rs1435277933 5412 dbSNP
rs1264107906 5413 dbSNP
rs1325151569 5414 dbSNP
rs1424687730 5423 dbSNP
rs972115442 5425 dbSNP
rs181985185 5426 dbSNP
rs923508218 5435 dbSNP
rs933553043 5441 dbSNP
rs1166638101 5443 dbSNP
rs574552418 5446 dbSNP
rs1419940203 5449 dbSNP
rs1187270631 5450 dbSNP
rs917042565 5455 dbSNP
rs186117390 5472 dbSNP
rs947549461 5486 dbSNP
rs1482729642 5489 dbSNP
rs1476484930 5491 dbSNP
rs980942105 5498 dbSNP
rs549616238 5506 dbSNP
rs563606290 5510 dbSNP
rs1343555468 5526 dbSNP
rs936923841 5527 dbSNP
rs1042814686 5528 dbSNP
rs1370209286 5532 dbSNP
rs1276193817 5534 dbSNP
rs902957849 5535 dbSNP
rs1349323608 5541 dbSNP
rs914127524 5546 dbSNP
rs563332645 5556 dbSNP
rs1362036080 5564 dbSNP
rs1431517533 5564 dbSNP
rs934317591 5564 dbSNP
rs1355002054 5565 dbSNP
rs1175305110 5566 dbSNP
rs945437020 5570 dbSNP
rs1056833752 5576 dbSNP
rs1052160078 5581 dbSNP
rs1177407548 5582 dbSNP
rs895480921 5583 dbSNP
rs1007571797 5585 dbSNP
rs1012796278 5589 dbSNP
rs1022855228 5590 dbSNP
rs888253534 5591 dbSNP
rs532373745 5593 dbSNP
rs1237361520 5594 dbSNP
rs1005373101 5602 dbSNP
rs1016285704 5613 dbSNP
rs34929202 5616 dbSNP
rs1262757775 5620 dbSNP
rs761638079 5622 dbSNP
rs1026266693 5624 dbSNP
rs972564715 5624 dbSNP
rs994618966 5624 dbSNP
rs1411079480 5626 dbSNP
rs1373450364 5633 dbSNP
rs1354726387 5634 dbSNP
rs1415124949 5634 dbSNP
rs1360666818 5639 dbSNP
rs545759962 5643 dbSNP
rs1176948453 5671 dbSNP
rs137885454 5677 dbSNP
rs954890973 5685 dbSNP
rs1255506771 5687 dbSNP
rs1409978932 5690 dbSNP
rs986350661 5696 dbSNP
rs1183018078 5705 dbSNP
rs528391690 5707 dbSNP
rs1013921865 5714 dbSNP
rs1161674806 5718 dbSNP
rs910835506 5719 dbSNP
rs1180611551 5726 dbSNP
rs947518803 5733 dbSNP
rs978963320 5744 dbSNP
rs548142635 5746 dbSNP
rs1184467335 5747 dbSNP
rs574541499 5749 dbSNP
rs1381259187 5753 dbSNP
rs530867728 5754 dbSNP
rs1419946955 5762 dbSNP
rs1463843424 5766 dbSNP
rs969806646 5768 dbSNP
rs551101755 5776 dbSNP
rs1316986960 5780 dbSNP
rs765263488 5789 dbSNP
rs1467120087 5793 dbSNP
rs1303408416 5799 dbSNP
rs768588181 5802 dbSNP
rs895460409 5808 dbSNP
rs958220814 5816 dbSNP
rs948403727 5822 dbSNP
rs570947981 5838 dbSNP
rs1044280182 5848 dbSNP
rs1389562790 5849 dbSNP
rs1454561539 5852 dbSNP
rs1349350494 5862 dbSNP
rs540059847 5878 dbSNP
rs1162818842 5884 dbSNP
rs1425668752 5886 dbSNP
rs546959425 5902 dbSNP
rs1188504335 5906 dbSNP
rs1447976891 5916 dbSNP
rs1250369712 5918 dbSNP
rs888390830 5922 dbSNP
rs750223904 5924 dbSNP
rs1486016611 5925 dbSNP
rs1015344749 5926 dbSNP
rs1264315258 5928 dbSNP
rs896980953 5929 dbSNP
rs142415360 5930 dbSNP
rs766311252 5939 dbSNP
rs1315574655 5940 dbSNP
rs1227580049 5948 dbSNP
rs1362763270 5951 dbSNP
rs911871068 5961 dbSNP
rs943356211 5964 dbSNP
rs1390240193 5965 dbSNP
rs1292027639 5966 dbSNP
rs781544908 5968 dbSNP
rs1366281757 5970 dbSNP
rs3209335 5971 dbSNP
rs1392386716 5978 dbSNP
rs899249318 5984 dbSNP
rs1432995745 5987 dbSNP
rs994721651 5987 dbSNP
rs1189109856 5991 dbSNP
rs754692339 5991 dbSNP
rs73317872 5992 dbSNP
rs1023990233 5994 dbSNP
rs1250796548 5995 dbSNP
rs780555399 5996 dbSNP
rs1227828939 6000 dbSNP
rs986154483 6020 dbSNP
rs1017866449 6031 dbSNP
rs769946050 6036 dbSNP
rs2273623 6046 dbSNP
rs1407069501 6049 dbSNP
rs1346221132 6054 dbSNP
rs979017256 6060 dbSNP
rs1239180710 6062 dbSNP
rs1001187381 6063 dbSNP
rs1454105932 6065 dbSNP
rs368608522 6068 dbSNP
rs1192687103 6075 dbSNP
rs1169019498 6078 dbSNP
rs1465803034 6084 dbSNP
rs1376285072 6087 dbSNP
rs757673105 6099 dbSNP
rs1268940079 6106 dbSNP
rs956422521 6115 dbSNP
rs992561828 6119 dbSNP
rs1196315174 6122 dbSNP
rs917016587 6128 dbSNP
rs1434439489 6132 dbSNP
rs914028527 6137 dbSNP
rs1225562559 6138 dbSNP
rs948372677 6153 dbSNP
rs1324582036 6156 dbSNP
rs1287995094 6157 dbSNP
rs1176196800 6164 dbSNP
rs1337624110 6166 dbSNP
rs1330062438 6171 dbSNP
rs1353364033 6174 dbSNP
rs1396027912 6176 dbSNP
rs1460415540 6179 dbSNP
rs967006129 6182 dbSNP
rs779522264 6183 dbSNP
rs909797626 6185 dbSNP
rs941240645 6195 dbSNP
rs1037371791 6208 dbSNP
rs896957347 6214 dbSNP
rs1301583300 6216 dbSNP
rs1370047239 6225 dbSNP
rs1471287550 6227 dbSNP
rs943410028 6232 dbSNP
rs189794314 6246 dbSNP
rs565619606 6255 dbSNP
rs930686150 6261 dbSNP
rs1428602504 6268 dbSNP
rs1305775142 6270 dbSNP
rs1461618519 6272 dbSNP
rs1051836981 6273 dbSNP
rs1226797851 6273 dbSNP
rs1047569140 6275 dbSNP
rs1280272466 6287 dbSNP
rs1244671894 6288 dbSNP
rs1288164463 6288 dbSNP
rs746394415 6303 dbSNP
rs1317804810 6304 dbSNP
rs886246956 6321 dbSNP
rs1453762594 6323 dbSNP
rs949894945 6325 dbSNP
rs1319469447 6335 dbSNP
rs1045706580 6338 dbSNP
rs1007557906 6341 dbSNP
rs138397437 6342 dbSNP
rs1366598305 6348 dbSNP
rs1255239463 6349 dbSNP
rs1489269910 6357 dbSNP
rs1191354979 6367 dbSNP
rs1017583283 6368 dbSNP
rs1001239885 6372 dbSNP
rs968709819 6375 dbSNP
rs1207045063 6380 dbSNP
rs534746468 6391 dbSNP
rs1449004866 6409 dbSNP
rs892905181 6418 dbSNP
rs1209264292 6421 dbSNP
rs1354349233 6427 dbSNP
rs576940457 6436 dbSNP
rs1000425953 6460 dbSNP
rs1020015993 6462 dbSNP
rs967311193 6488 dbSNP
rs1424218877 6516 dbSNP
rs1032353777 6517 dbSNP
rs182615805 6519 dbSNP
rs1019197339 6527 dbSNP
rs149623464 6542 dbSNP
rs964894641 6560 dbSNP
rs1404187566 6564 dbSNP
rs956220116 6569 dbSNP
rs1437466046 6574 dbSNP
rs772384478 6578 dbSNP
rs1132794 6582 dbSNP
rs548002021 6598 dbSNP
rs920565590 6599 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
IDDuplex structurePosition
1 
miRNA  3' guguuugguAAUACACGACGAu 5'
                   |||| ||||||| 
Target 5' -------ucUUAUUUGCUGCUa 3'
 		1 - 15
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000395076.4 | 3UTR | UCUUAUUUGCUGCUAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.751 1.8e-5 0.673 2.2e-4 23 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.704 2.7e-4 0.741 9.3e-5 20 Click to see details
GSE19536 Breast cancer 0.263 4.1e-3 0.270 3.3e-3 100 Click to see details
GSE19783 ER- ER- breast cancer 0.273 7.5e-3 0.249 1.3e-2 79 Click to see details
GSE19350 CNS germ cell tumors 0.66 9.8e-3 0.455 6.9e-2 12 Click to see details
GSE38226 Liver fibrosis -0.483 1.3e-2 -0.343 6.4e-2 21 Click to see details
GSE21032 Prostate cancer 0.193 4.0e-2 0.180 5.2e-2 83 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.338 4.9e-2 0.123 2.8e-1 25 Click to see details
GSE21849 B cell lymphoma 0.162 2.0e-1 0.193 1.6e-1 29 Click to see details
GSE28260 Renal cortex and medulla -0.22 2.4e-1 -0.264 1.9e-1 13 Click to see details
GSE28544 Breast cancer -0.131 2.7e-1 0.056 4.0e-1 24 Click to see details
GSE17498 Multiple myeloma -0.092 2.9e-1 -0.108 2.5e-1 40 Click to see details
GSE27834 Pluripotent stem cells 0.151 2.9e-1 0.079 3.9e-1 16 Click to see details
GSE17306 Multiple myeloma 0.076 3.0e-1 0.110 2.3e-1 49 Click to see details
GSE14794 Lymphoblastoid cells 0.049 3.2e-1 -0.062 2.8e-1 90 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.092 3.3e-1 -0.056 4.0e-1 25 Click to see details
GSE32688 Pancreatic cancer 0.044 4.1e-1 0.191 1.5e-1 32 Click to see details
GSE26953 Aortic valvular endothelial cells 0.031 4.4e-1 0.022 4.6e-1 24 Click to see details
GSE19783 ER+ ER+ breast cancer 0.015 4.7e-1 0.202 2.0e-1 20 Click to see details
GSE21687 Ependynoma primary tumors 0.003 4.9e-1 0.006 4.8e-1 64 Click to see details
GSE21687 Ependynoma primary tumors 0.003 4.9e-1 0.006 4.8e-1 64 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
STAD -0.619 0 -0.618 0 32 Click to see details
BRCA 0.289 0 0.165 0.07 84 Click to see details
THCA -0.328 0.01 -0.388 0 59 Click to see details
BLCA -0.508 0.02 -0.531 0.01 18 Click to see details
LUAD -0.57 0.03 -0.490 0.05 12 Click to see details
KIRP -0.308 0.04 -0.272 0.07 32 Click to see details
LIHC -0.205 0.08 -0.184 0.1 49 Click to see details
COAD -0.461 0.13 -0.667 0.04 8 Click to see details
HNSC -0.15 0.17 -0.200 0.1 42 Click to see details
PCPG -0.856 0.17 -1.000 0.5 3 Click to see details
PRAD -0.136 0.17 -0.094 0.26 50 Click to see details
ESCA -0.28 0.2 -0.345 0.15 11 Click to see details
CHOL -0.289 0.23 -0.083 0.42 9 Click to see details
CESC 0.657 0.27 0.500 0.33 3 Click to see details
KICH 0.122 0.28 0.181 0.19 25 Click to see details
UCEC 0.127 0.3 0.028 0.45 19 Click to see details
LUSC -0.073 0.33 -0.064 0.35 38 Click to see details
KIRC -0.014 0.45 -0.007 0.48 68 Click to see details
PAAD 0.015 0.49 0.000 0.5 4 Click to see details
PAAD 0.015 0.49 0.000 0.5 4 Click to see details
PAAD 0.015 0.49 0.000 0.5 4 Click to see details
MiRNA Regulatory Network:
Functional analysis:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR) Other evidence
Transcription factor regulation Circular RNA sponge
694 hsa-miR-15a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000280 BMI1 BMI1 proto-oncogene, polycomb ring finger 5 3
MIRT000282 WNT3A Wnt family member 3A 3 2
MIRT000283 MYB MYB proto-oncogene, transcription factor 5 3
MIRT000284 CDC25A cell division cycle 25A 4 4
MIRT000285 CCND2 cyclin D2 4 7
MIRT000804 RAB9B RAB9B, member RAS oncogene family 1 1
MIRT000806 ACTR1A ARP1 actin related protein 1 homolog A 1 1
MIRT000808 TPI1 triosephosphate isomerase 1 1 1
MIRT000810 PDCD4 programmed cell death 4 3 2
MIRT000812 RAB21 RAB21, member RAS oncogene family 2 1
MIRT000815 BCL2 BCL2, apoptosis regulator 6 13
MIRT000817 WT1 Wilms tumor 1 2 1
MIRT000819 ASXL2 additional sex combs like 2, transcriptional regulator 2 1
MIRT000823 TMEM251 transmembrane protein 251 2 1
MIRT000825 CARD8 caspase recruitment domain family member 8 2 1
MIRT000827 CDC14B cell division cycle 14B 2 1
MIRT000829 CENPJ centromere protein J 2 1
MIRT000831 CEP63 centrosomal protein 63 2 1
MIRT000833 CREBL2 cAMP responsive element binding protein like 2 4 5
MIRT000835 ECHDC1 ethylmalonyl-CoA decarboxylase 1 2 1
MIRT000847 GOLGA5 golgin A5 2 1
MIRT000849 GOLPH3L golgi phosphoprotein 3 like 2 1
MIRT000851 GTF2H1 general transcription factor IIH subunit 1 2 1
MIRT000853 H3F3B H3 histone family member 3B 2 1
MIRT000855 HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2 1
MIRT000857 HDHD2 haloacid dehalogenase like hydrolase domain containing 2 2 1
MIRT000859 HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2 1
MIRT000863 HRSP12 reactive intermediate imine deaminase A homolog 2 1
MIRT000865 HSDL2 hydroxysteroid dehydrogenase like 2 2 1
MIRT000866 HSPA1A heat shock protein family A (Hsp70) member 1A 2 1
MIRT000868 JUN Jun proto-oncogene, AP-1 transcription factor subunit 2 1
MIRT000878 MCL1 MCL1, BCL2 family apoptosis regulator 2 1
MIRT000880 MSH2 mutS homolog 2 2 1
MIRT000884 OMA1 OMA1 zinc metallopeptidase 2 1
MIRT000886 OSGEPL1 O-sialoglycoprotein endopeptidase like 1 2 1
MIRT000888 PDCD6IP programmed cell death 6 interacting protein 2 1
MIRT000890 PHKB phosphorylase kinase regulatory subunit beta 2 1
MIRT000892 PMS1 PMS1 homolog 1, mismatch repair system component 2 1
MIRT000894 PNN pinin, desmosome associated protein 2 1
MIRT000896 PRIM1 DNA primase subunit 1 2 1
MIRT000898 RAD51C RAD51 paralog C 2 1
MIRT000900 RHOT1 ras homolog family member T1 2 1
MIRT000902 RNASEL ribonuclease L 2 1
MIRT000906 SLC35A1 solute carrier family 35 member A1 2 1
MIRT000908 SLC35B3 solute carrier family 35 member B3 2 1
MIRT000910 TIA1 TIA1 cytotoxic granule associated RNA binding protein 2 1
MIRT000914 UGDH UDP-glucose 6-dehydrogenase 2 1
MIRT000916 UGP2 UDP-glucose pyrophosphorylase 2 2 1
MIRT000922 ZNF559 zinc finger protein 559 2 1
MIRT001227 CCND1 cyclin D1 6 8
MIRT001228 CCNE1 cyclin E1 7 10
MIRT001802 BACE1 beta-secretase 1 2 1
MIRT002946 DMTF1 cyclin D binding myb like transcription factor 1 4 4
MIRT003330 RPS6 ribosomal protein S6 0 1
MIRT003333 BRCA1 BRCA1, DNA repair associated 2 2
MIRT003334 AKT3 AKT serine/threonine kinase 3 3 6
MIRT003872 WIPF1 WAS/WASL interacting protein family member 1 2 1
MIRT003873 VPS45 vacuolar protein sorting 45 homolog 2 1
MIRT003874 HSP90B1 heat shock protein 90 beta family member 1 2 1
MIRT003875 SKAP2 src kinase associated phosphoprotein 2 3 1
MIRT003876 NT5DC1 5'-nucleotidase domain containing 1 2 1
MIRT003877 FAM69A family with sequence similarity 69 member A 2 1
MIRT003878 C2orf74 chromosome 2 open reading frame 74 1 1
MIRT003879 FAM122C family with sequence similarity 122C 2 1
MIRT003880 PWWP2A PWWP domain containing 2A 2 1
MIRT003881 C17orf80 chromosome 17 open reading frame 80 2 1
MIRT003882 CCDC111 primase and DNA directed polymerase 2 1
MIRT003883 C2orf43 lipid droplet associated hydrolase 2 1
MIRT003884 C4orf27 histone PARylation factor 1 2 1
MIRT003885 NIPAL2 NIPA like domain containing 2 2 1
MIRT003886 TRMT13 tRNA methyltransferase 13 homolog 2 1
MIRT003887 ANAPC16 anaphase promoting complex subunit 16 2 1
MIRT003888 CADM1 cell adhesion molecule 1 3 1
MIRT003891 TMEM184B transmembrane protein 184B 2 1
MIRT003899 APP amyloid beta precursor protein 4 3
MIRT004046 UCP2 uncoupling protein 2 3 1
MIRT004275 VEGFA vascular endothelial growth factor A 7 17
MIRT004680 TSPYL2 TSPY like 2 2 1
MIRT004829 NFKB1 nuclear factor kappa B subunit 1 3 1
MIRT005552 CHUK conserved helix-loop-helix ubiquitous kinase 4 1
MIRT005763 TP53 tumor protein p53 1 1
MIRT006027 FGF7 fibroblast growth factor 7 2 1
MIRT006176 CLCN3 chloride voltage-gated channel 3 4 1
MIRT006177 CRKL CRK like proto-oncogene, adaptor protein 6 3
MIRT006181 MN1 MN1 proto-oncogene, transcriptional regula