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miRTarBase - #MIRT023246 -
pre-miRNA Information
pre-miRNA hsa-mir-122   
Genomic Coordinates chr18: 58451074 - 58451158
Synonyms MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, MIR122
Description Homo sapiens miR-122 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-122-5p
Sequence 15| UGGAGUGUGACAAUGGUGUUUG |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 18 + 58451091 29233923 MiREDiBase
C-to-U 11 18 + 58451098 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1258166649 1 dbSNP
rs1426570658 6 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TBL1XR1   
Synonyms C21, DC42, IRA1, MRD41, TBLR1
Description transducin beta like 1 X-linked receptor 1
Transcript NM_024665   
Expression
Putative miRNA Targets on TBL1XR1
3'UTR of TBL1XR1
(miRNA target sites are highlighted)		 
>TBL1XR1|NM_024665|3'UTR
   1 CGCTACTAGTTGGAAGCCATGGACCGACTATGAATGTGTACATAGCCAAAATGACTGTCCCTGACCCATGTACTGCTATA
  81 GTCCCACTTGAACCATGGCCAGTCCACTACAGCCAAATCTAAAAGAAATATATACATACAGTGTATATAAACAAAATTGC
 161 ACCCTGAAGATGACAGAGTTTTGTCACAGCTTGTGAATTCTGTTCACCAAGTGCTGGAATCTAATCTGCTGTGCCCCTAA
 241 AATAGCATTTAGAAGTTTTGGATATGAAAAACAGAAGAGAGAAAAATATACATTATAAAAGCAGAACATACATGTACCAG
 321 TTTTTGGATACTAAATGACAGCCTTGTTTCTCCCCTTTGAATCAGCAGACACCATGGATTATATTCTTTTTTTCCCTTCA
 401 GTAGTGAGCAGTTTGTATGTACAGAGAAAATGGACTTACAAAAACTTGCAGCAGTAGTTTGTTCTTGCTTTAAAATTTCG
 481 TTTTTGGTTTAGATTATGGATGCATGAAGTAAGGGAGTGAATCAGTTTCTTGTTTATATTTTTTTCACCTTTTAAACAAA
 561 AAATTCTTTAAAATATTTTAATGCATTCTTTTGAAGAGGTAGATGTTTGGTACATTTTATGGCTCCCAGAGCATATATTC
 641 AGTTGGTGCATGTTGTGGAAGGGGGAATTGGAAATTAAATGAAAACCTATGACTTTGGTCATGTCAATCTGTAAGACACA
 721 TCAGTAAAAGGGTATTATGCTCTGTTGGTTTTGTTTTTTTGTTTTGCTTTTTTTTTTTTTTTTTCTTTTTTGTTTTTTGG
 801 TGATGTGGCTTAAATGCAATAGTTTCTTTTTTGGGACATATTTCTGCCAATTAAAGACTAGAAGGGCACAACTTTTTTTT
 881 TAATTACCATAGAGAAGATACATTAAAAAAAATCTTCTGATGTTTTGTAGCCATAACTAAATTATGGTAAAAATGTGCAC
 961 TATTGTGAAAAGGAGCAACGTAGTTTTGGGTTTTTTGTTGTTTGTTTGTTTTGCTTTGTTTTTTAAGAGATTAAAATGTT
1041 TCTGGATAAGGATTAGCTTCTCGAAGTGTCCATCATTCTGTGTAGAAGCTTAAATATGTAATGTAACCAAACTCCAGTAT
1121 TAAAAATCTCTCATGTTGTTTTCTTTATACAAAGCAAGATAACGGCATATAACACTGCCATTACATGGCAAAATGTTTGC
1201 TACCTTAGTTTAAAAAACAATCTCAAACAAAAGACTTGCTTCAAGGTGTTTTTAAATAGCAGTGATTCAGAATTTTTTTT
1281 AATGAAAGTATAATTGCACTAACCTTCTTCCTGCTGCTCTGATTCTGCATTTGTGGTACTTGTGACTACGTTTTTTCAAA
1361 TATAGATAGATTTAAGCTGCTAATTTTTTTTTTTTTAGTAATCACTACTATATCATGTCTTTTACTCTGTTTATAATATC
1441 AAGTATTTTCTTAAAGATATAGATATTAAACCTTGTGCTCATGCAACTTAGAGTAACATATACAGACAAATGATTGCATG
1521 AGGCCATGTTTATATGTGTGACTAATAAGGCTTGTCATGATTAACATAATCCAGGTATGTCATTTCTGAAGAGAATAGTC
1601 ATCAAATTTATATCTCGAAGATTTTAATTAAGGAATTGCTTATTGTTGAGCTTAGCAAATTAATAACACTATTTCTGTCA
1681 CTAATTATTTTGAGGCCTTTTAGTACTAAAATTTTAACCTGTGTTCTAAGTAGAAACTGATTTAACCCAAGTAATGCAGC
1761 TTTGATTGATTTCAGCATTCGTTGCTTTGCTATTTTTACAAAACAGCATTGATTGAAGCAAGTCTTGGTTTTACTAAGGT
1841 AGGGTAGCATTTGCTATTGGTAAAGAGAATAAATACACTTAATTTCACAATACATTGTTATATGTACCCCAGTTGTTGTT
1921 AGTGGGGACTATGATACTGTAATAATATTTTTAAAAATTTACATCAAGAGAGGCAGTCATTCACGATGGTTTTGTGCCAG
2001 CTCTTTTTAGGGTTTTGGATCACATTAGAGATATTTAGAACATATTACCCTGTGACTTACGTAGGAAACCTAATATGCTG
2081 AGTATCTGGCACTTGAATTCCTGCTTTTATTGCTGGAGGTCCACATCTGTGGTTGACCTCTGTTATTGTTTAAAAAAAAT
2161 AAATAAAAATTAAAAAAATCTGTGCAATAATTTTAAAATGTGCTCCCAGGAATAGACACAAATGTTTTGAGTATCTTTTA
2241 AGCTGCATTTTCCTTTAGTGATGCATTTGTCAATTGCACTGAATTTAAATCTGAAAGTCAGAGGTGATTATTGATAGTAC
2321 TTTTGTATTTTGATATGGACAGTTTATTCATTTGCATACAGTTATTGACTTTTTCCCAGCTGATTAAAAGATAGTCAAGA
2401 AATTCTGCAATATAGCTGCCAAAATAGACAGCTACATTTTTATGATATTGTCATCTTTTCTGTTTTTTTTTTCTTTTTTT
2481 TCTTTAGCTATTTTACTTAAGCATAATAGCCACAATAGGACATATAAAAGATTATAAATACAGAGCTTTATTATCCTGAC
2561 GTCTTGGGTCTTTTAAGTATATACTTTTCTGAAAGGTATCCATTTTGTAGGCTTGGGTTCTTCATGAGCATACGATTGTT
2641 TATTTTTGCTGCTGTTCTCAACATCATCATTGCCTGCTGATGTGCCACGATGCTGCTCCAATAGACAGCAATAAGATTGT
2721 CTCTAATTTGAGCAGTAACATGATTGCAAGAGACCAAGTTTCACAGCTTGTAAAGTTCTGTATTTGGGATTCTTGCTTAT
2801 TTTTCCGCCTGTGTTTTTCTGAGAACTTATTCCTGATGATCAATTGAATCCAGTAGTTTTTCTATGCTATTTGTTGTTGT
2881 ATAAGCTACTGTAAGAAACTTATCATAAGGAAAAATAGAAAGGAAAACTTGAATCAATACTCATTGATTAAAATGGAATA
2961 AAGAAAGAGCAGCTGCCACTTTTAAACAACATAAAGGAATATCTTTTTTTGTCTCCGTGTAGGAAATCCCATAAGTTCTT
3041 ATATTTGTTCCAGTTCCCATTTCCTGCCATTGACCAGATAACATCATTGACTTTCAAATGACTTTTAGAAGTGATAACTC
3121 TTAATTTCCTAATAGATACTAGATTGTATTGAATTCTGTTTTAATTATTCTCTAGGTAAGTATGTTTTAGGATTAAATAC
3201 CTTTTACAGATACTGAAAGTGCCTCCTTTTGTGGTGTAAAAAACAAATTATGGTGCAAAAAGTAATCACTAGATTGAAAT
3281 ACATGAAGGTTTTTTGCTTTTTGACATACGAAAATGTCAAGAGAAAGGCCAAAGATTTGTACTTTTTCACTTACAAAGCA
3361 CTCCTTTTTCCCTTAAACTTCTTTCTGTCAAATTAGATTTAATGAGAGAGTACTATTTTTAAGGAGCTATCTGTTTATGT
3441 AGAATGATTTTGTTAAGAGTAATGTAAACTATTATTGAGTAGAGGCCTAAAGAGGACTGTGCATTTTTGCTATTTAAAGG
3521 AATCACAAATGATCATACTTAAGTGAGCAAAAATGACAAGTTTTACTAGCTAAGTAGAGAAATAAATCTCAAATGCAGCG
3601 CTACAATTTTCATTATCTTAAGTACATTGTACATTTCTACAGAACCTGTGATTATTCTCGCATGATAAGGATGGTACTTG
3681 CATATGGTGAATTACTACTGTTGACAGTTTCCGCAGAAATCCTATTTCAGTGGACCAACATTGTGGCATGGCAGCAAATG
3761 CCAACATTTTGTGGAATAGCAGCAAATCTACAAGAGACCCTGGTTGGTTTTTCGTTTTGTTTTCTTTGTTTTTTCCCCCT
3841 TCTCCTGAATCAGCAGGGATGGAAGGAGGGTAGGGAAGTTATGAATTACTCCTTCCAGTAGTAGCTCTGAAGTGTCACAT
3921 TTAATATCAGTTTTTTTTAAACATGATTCTAGTTAAATGTAGAAGAGAGAAGAAAGAGGAAGTGTTCACTTTTTTAATAC
4001 ACTGATTTAGAAATTTGATGTCTTATATCAGTAGTTCTGAGGTATTGATAGCTTGCTTTATTTCTGCCTTTACGTTGACA
4081 GTGTTGAAGCAGGGTGAATAACTAGGGCATATATTTTTTTTTTTTTTGTAAGCTGTTTCATGATGTTTTCTTTGGAATTT
4161 CCGGATAAGTTCAGGAAAACATTCTGCATGTTGTATCTAGTCTGATGTACTTATCCATCTCATTACAAACAAAAACACAC
4241 AGACTGCATTTGTAGCTCTGTAATCCTTGAATACGGAAGTAAATTTTCTTCTTTCCTGACTTTGACATTGTAGCTATACT
4321 GTTTCCATTTTTGTTTTTACAAATCCTTTGGGTCTAATTCTGTGAGCCTACCTATAGCACTGGATTAAAATGTCTGCATC
4401 ATTTCTTTAGTTATCCAGTTAACTTTAAAACTGTTGTAAAAGTGTAAACCAGCCCATGACAGGTTTTTGTACATGTTAAA
4481 GAACTTCATTGTTCAGTTTTCATGATTATTGTGTAAGGAAGACTGATGTAGATGTTCTGTGCTGTCCTGGACCATGTTAA
4561 TTACACTTACGACGTATTTTAGTTCCACATCACAATGATTTGTCCCCAGTGACCCTTTTATCCTTTCTAGGCACATTTCT
4641 TGTTGTTGTTGTTGTTGCAGTTCCCCTTTGCATTGTATTGCTTTGACAACTGTAATTTGAATCAGATCTGAAAGAGGTCC
4721 AGAATAAAATATATTTTGATATTATGTTGGCTGTGTACATATATAAAACCTTTGATGTCTATGTAGTTTATATAGACTAT
4801 TTACTAGTCAGGTAAAGAGAGAGGGATGGTATTTCTTGTTTACAGTTTGTTTACATTTTAATTGCTTTTACTTCTCCAGT
4881 GTTCTATTGTAGAATAAACCTTTTTTTCCAAGTTAGCCTTCATAACCTATAACACATTCATTCTCTCCCATACTGGTGTT
4961 ACTGATTAATAACTGCCATCAGAACCCAAACCACTGTTTTTCATAAACGTATTGTTTCCCAAGATATATACTTTAAGCCC
5041 ATAATAAAATTACAAATTTTACTATTTTTATTACTTCTTGCAGGAGATAAGATTTTTTTAAATGAAGGGGTTATTTACTA
5121 TTTTTATTAAAGTATAATAGAGCATCTAATCAGCTAAGGGATTGTAATTTTTAATTCTTTTGAAAAATAAATATTGTATT
5201 TAAAAGACGTTATTTCACAGAAGCTGAAAAAGAGACCTTAGATAACATTTGTTTGGTTAGCCACACGGTTGAGCACAAAA
5281 CAATGTGTAGATGTGTTGAAGATTAGGGCAGGAGGCTCAACTTCTCGGTGACCTTTTTTTGCTTCACAACAAGCCAATTA
5361 TAGTTGAATCATTTTCTCTCTTAGCTAGTTGTTACTACAAACTTTATAAGAAAAACAACTAGACACCTTCTAGTTTTAAT
5441 TAATACCAACTCCTTTAGAGTTAGAGACTTTTTAAAAAGAATCATTGAGCATATTTTCTTTTTTTTTTTTTTAAGAATTT
5521 ACACTCTCTAGGTCTTCTATTTTTCCTGTTTATTTCCTTAAACAGAAATAAATTCAAGCATAGTTTTATGTTTTATTAGA
5601 AATAAGCCACTGCAGTTGCTAGAACTGACATGCTTTCATTTTCAAGGGGTTAACTTTTATTGCATGGCATAGATTATTAG
5681 TAATATCCTGCATTGTATACTTTTCCAAAAAGGGTTGGACTCCTAAGGATTAGAATCCTTATAAGCTTGAGGGAAAGCTG
5761 AAACTAATTTGAACAGTAATAGAAGGGATTATTTTTAATTTCATAGTTAACACTTTACAATGGATTAGATTTATTACCTA
5841 GTATAATCCGTAGCAGATCAGATCAAAGTTTACTGTTTTACCAATATATTCATTTGAAAAAATACAGTGGAGGAAAAGAC
5921 ACTTTAGATGGTAGTTTTATGGTGCTTTTCTCTGCTGTACCAAAGTGCTTTGTCATCAATGAAATGTTAACCCTATGCTA
6001 CTTTTTCTGCATGCTTCTTAAATGTCATCTTAATGCTTAATTGTCCTAACTTGTAATATTTTTGTATTAAATTTTTTTAG
6081 GAGTTCCTTGTAATTTCTTTACAATTTAAAATATATTAAACACAAAGTGTTTAGTAAAGTACAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1 
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            |::| |||||| |||:|:| 
Target 5' taAGTA-CATTGT-ACATTTCt 3'
 		3619 - 3638 134.00 -13.00
2 
miRNA  3' guUUGUGGUAACAGUGUGAGGu 5'
            || |  ||  |:||||||: 
Target 5' ttAAGA--AT--TTACACTCTc 3'
 		5511 - 5528 132.00 -8.90
3 
miRNA  3' guUUGUGGUAACAG-UGUGAGGu 5'
            ||: :||| ||: |||||:: 
Target 5' ttAATTTCATAGTTAACACTTTa 3'
 		5795 - 5817 132.00 -11.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN14047925 1 COSMIC
COSN31537208 2 COSMIC
COSN18728078 11 COSMIC
COSN30500692 39 COSMIC
COSN30113352 51 COSMIC
COSN30516641 78 COSMIC
COSN30517987 110 COSMIC
COSN14047923 116 COSMIC
COSN31514129 125 COSMIC
COSN30127807 141 COSMIC
COSN30115472 154 COSMIC
COSN31584585 200 COSMIC
COSN15661291 380 COSMIC
COSN31490198 399 COSMIC
COSN30174668 424 COSMIC
COSN26549728 523 COSMIC
COSN31607183 654 COSMIC
COSN31542964 724 COSMIC
COSN20090951 761 COSMIC
COSN28719507 766 COSMIC
COSN28709250 767 COSMIC
COSN19662214 785 COSMIC
COSN20099412 872 COSMIC
COSN23710792 894 COSMIC
COSN7837226 954 COSMIC
COSN31602613 971 COSMIC
COSN31596100 998 COSMIC
COSN15140785 1010 COSMIC
COSN32064005 1042 COSMIC
COSN31569666 1117 COSMIC
COSN26463584 1135 COSMIC
COSN29873409 1164 COSMIC
COSN31549455 1222 COSMIC
COSN30543362 1228 COSMIC
COSN28201084 1276 COSMIC
COSN22340578 1280 COSMIC
COSN28201086 1323 COSMIC
COSN31535996 1333 COSMIC
COSN30335352 1350 COSMIC
COSN31959897 1461 COSMIC
COSN7627395 1951 COSMIC
COSN1933060 1963 COSMIC
COSN31544663 1985 COSMIC
COSN20687228 2003 COSMIC
COSN31561834 2040 COSMIC
COSN31549040 2065 COSMIC
COSN1933059 2084 COSMIC
COSN31594012 2114 COSMIC
COSN31523891 2143 COSMIC
COSN31523873 2147 COSMIC
COSN31607685 2151 COSMIC
COSN31568130 2156 COSMIC
COSN5528909 2267 COSMIC
COSN31520404 2282 COSMIC
COSN28725368 2338 COSMIC
COSN26677352 2340 COSMIC
COSN31521876 2462 COSMIC
COSN31535995 2673 COSMIC
COSN31485223 2762 COSMIC
COSN30173907 2829 COSMIC
COSN15407948 2922 COSMIC
COSN31550762 2928 COSMIC
COSN31584991 3038 COSMIC
COSN31549450 3126 COSMIC
COSN31568982 3190 COSMIC
COSN26646799 3222 COSMIC
COSN26645167 3228 COSMIC
COSN31547812 3381 COSMIC
COSN31528287 3599 COSMIC
COSN28675159 3623 COSMIC
COSN31584799 3660 COSMIC
COSN31485741 3807 COSMIC
COSN15662493 3814 COSMIC
COSN31553390 4073 COSMIC
COSN20099408 4114 COSMIC
COSN6755228 4574 COSMIC
COSN17676982 5140 COSMIC
COSN17215128 5206 COSMIC
COSN25512469 5285 COSMIC
COSN9535655 5466 COSMIC
COSN7627393 5522 COSMIC
COSN21291200 5809 COSMIC
COSN6572968 5820 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs772530865 1 dbSNP
rs746182305 2 dbSNP
rs1425608924 4 dbSNP
rs757648589 8 dbSNP
rs1161462045 9 dbSNP
rs1441249261 17 dbSNP
rs367636842 18 dbSNP
rs1485736268 19 dbSNP
rs777331745 20 dbSNP
rs1417198146 26 dbSNP
rs547301798 36 dbSNP
rs1268921704 40 dbSNP
rs1199488594 41 dbSNP
rs1333932445 42 dbSNP
rs1490087638 47 dbSNP
rs375368882 48 dbSNP
rs1212576741 59 dbSNP
rs1013682864 64 dbSNP
rs895377507 74 dbSNP
rs1422883069 76 dbSNP
rs1187230677 77 dbSNP
rs1364760898 78 dbSNP
rs1327569353 84 dbSNP
rs371995470 86 dbSNP
rs1287915738 92 dbSNP
rs1443248858 93 dbSNP
rs1157422267 94 dbSNP
rs748543955 103 dbSNP
rs1359970222 106 dbSNP
rs1435477054 116 dbSNP
rs188090374 119 dbSNP
rs942164013 125 dbSNP
rs887977940 130 dbSNP
rs781609302 131 dbSNP
rs1329246927 139 dbSNP
rs556540273 141 dbSNP
rs1386346228 142 dbSNP
rs1047838509 148 dbSNP
rs1347959836 150 dbSNP
rs1393638553 154 dbSNP
rs929365753 157 dbSNP
rs1253768726 159 dbSNP
rs923355883 170 dbSNP
rs1196064933 173 dbSNP
rs1165614406 176 dbSNP
rs1462800293 185 dbSNP
rs183432695 200 dbSNP
rs1380160223 201 dbSNP
rs1455091199 231 dbSNP
rs1178279132 250 dbSNP
rs1376023170 262 dbSNP
rs943382946 273 dbSNP
rs1157590985 274 dbSNP
rs1444378553 279 dbSNP
rs1371589359 281 dbSNP
rs1388468739 282 dbSNP
rs1298532973 285 dbSNP
rs1470310270 287 dbSNP
rs1311145371 288 dbSNP
rs1227693340 289 dbSNP
rs1259649563 291 dbSNP
rs1315693904 308 dbSNP
rs911119339 314 dbSNP
rs577677315 316 dbSNP
rs1237990339 320 dbSNP
rs1489066228 328 dbSNP
rs751107861 333 dbSNP
rs1268570406 334 dbSNP
rs1212005043 337 dbSNP
rs1193479901 343 dbSNP
rs985371722 347 dbSNP
rs1196113037 350 dbSNP
rs760490162 351 dbSNP
rs752420789 352 dbSNP
rs767501359 353 dbSNP
rs957865209 354 dbSNP
rs1032097850 363 dbSNP
rs1169635879 366 dbSNP
rs1395005790 367 dbSNP
rs1459351668 370 dbSNP
rs978337604 374 dbSNP
rs1366268562 387 dbSNP
rs1467690625 389 dbSNP
rs1382237778 393 dbSNP
rs966457290 394 dbSNP
rs765835070 395 dbSNP
rs1217662614 397 dbSNP
rs759377593 402 dbSNP
rs1257803006 414 dbSNP
rs1322744753 415 dbSNP
rs1224424756 424 dbSNP
rs1264261513 438 dbSNP
rs773407015 439 dbSNP
rs1025165526 449 dbSNP
rs149609432 450 dbSNP
rs1216145797 454 dbSNP
rs7616373 464 dbSNP
rs1284017743 467 dbSNP
rs1406930591 470 dbSNP
rs1162443342 479 dbSNP
rs1224488925 480 dbSNP
rs867422131 481 dbSNP
rs894843167 484 dbSNP
rs1299448471 495 dbSNP
rs1358133060 497 dbSNP
rs750016079 499 dbSNP
rs1380335835 510 dbSNP
rs1033922229 513 dbSNP
rs1311038426 525 dbSNP
rs1321601680 529 dbSNP
rs1006515820 530 dbSNP
rs765017169 537 dbSNP
rs1288212989 538 dbSNP
rs1487387718 540 dbSNP
rs191817390 542 dbSNP
rs1216146734 546 dbSNP
rs1232583537 551 dbSNP
rs1397622657 557 dbSNP
rs1179859357 561 dbSNP
rs1412833128 564 dbSNP
rs1440214517 565 dbSNP
rs1377948159 566 dbSNP
rs796968918 569 dbSNP
rs1312974666 580 dbSNP
rs1047855309 582 dbSNP
rs1445402600 583 dbSNP
rs1326441364 585 dbSNP
rs1443053271 591 dbSNP
rs144236885 603 dbSNP
rs1317390610 616 dbSNP
rs1241501683 626 dbSNP
rs1401130021 643 dbSNP
rs1312172098 658 dbSNP
rs549340350 663 dbSNP
rs1352163653 674 dbSNP
rs1239427952 676 dbSNP
rs901903158 684 dbSNP
rs1040881858 686 dbSNP
rs1386675136 689 dbSNP
rs943369623 697 dbSNP
rs776470736 703 dbSNP
rs1054389679 707 dbSNP
rs936558587 718 dbSNP
rs1172616021 720 dbSNP
rs1426694461 722 dbSNP
rs78093177 732 dbSNP
rs567618807 738 dbSNP
rs1447905453 739 dbSNP
rs977930902 739 dbSNP
rs1448221664 747 dbSNP
rs371283137 748 dbSNP
rs1216952963 749 dbSNP
rs1333787759 750 dbSNP
rs1375271308 751 dbSNP
rs1018513693 753 dbSNP
rs1275487631 754 dbSNP
rs1347272822 755 dbSNP
rs1217688328 760 dbSNP
rs372185635 761 dbSNP
rs1330654284 765 dbSNP
rs1200224683 766 dbSNP
rs891259501 767 dbSNP
rs372049900 768 dbSNP
rs551017392 774 dbSNP
rs1457228278 778 dbSNP
rs1199539377 779 dbSNP
rs1247942650 785 dbSNP
rs1423807657 785 dbSNP
rs1467009853 785 dbSNP
rs1476788700 785 dbSNP
rs148659524 785 dbSNP
rs1491076346 785 dbSNP
rs201627324 785 dbSNP
rs879217781 785 dbSNP
rs966971453 785 dbSNP
rs780581150 790 dbSNP
rs1434328200 791 dbSNP
rs1258577255 792 dbSNP
rs866583640 792 dbSNP
rs1348632448 793 dbSNP
rs1220721591 799 dbSNP
rs1491283415 799 dbSNP
rs1236329476 800 dbSNP
rs1255897212 800 dbSNP
rs1491390992 800 dbSNP
rs1362925075 809 dbSNP
rs917663267 816 dbSNP
rs1263294718 819 dbSNP
rs1478583805 821 dbSNP
rs1421932332 826 dbSNP
rs1431152119 827 dbSNP
rs1346793857 830 dbSNP
rs1164216498 833 dbSNP
rs537140179 833 dbSNP
rs1404129818 836 dbSNP
rs992353112 838 dbSNP
rs959022530 844 dbSNP
rs1326087726 850 dbSNP
rs138323555 859 dbSNP
rs1285761320 867 dbSNP
rs1174964463 871 dbSNP
rs1427341190 873 dbSNP
rs1419389663 880 dbSNP
rs1187667751 881 dbSNP
rs1005896605 882 dbSNP
rs1213992410 882 dbSNP
rs777025983 882 dbSNP
rs1476566366 887 dbSNP
rs952243199 905 dbSNP
rs187377834 910 dbSNP
rs1370587506 913 dbSNP
rs993662573 913 dbSNP
rs368052605 914 dbSNP
rs1163554770 918 dbSNP
rs1161386886 927 dbSNP
rs1380984188 947 dbSNP
rs1421528409 953 dbSNP
rs1296423720 955 dbSNP
rs867197714 962 dbSNP
rs1040451115 979 dbSNP
rs1282803960 980 dbSNP
rs1007560623 981 dbSNP
rs1338523327 988 dbSNP
rs889207392 988 dbSNP
rs551947063 990 dbSNP
rs1355786741 997 dbSNP
rs1054357120 1003 dbSNP
rs528718994 1007 dbSNP
rs774598072 1011 dbSNP
rs771154419 1012 dbSNP
rs1201875434 1033 dbSNP
rs1258670283 1036 dbSNP
rs1203102146 1038 dbSNP
rs936022252 1060 dbSNP
rs183314004 1062 dbSNP
rs542864511 1064 dbSNP
rs552329726 1066 dbSNP
rs1042728146 1081 dbSNP
rs749527496 1086 dbSNP
rs773637241 1087 dbSNP
rs1156877910 1092 dbSNP
rs1363735124 1096 dbSNP
rs1291228881 1097 dbSNP
rs1414005114 1098 dbSNP
rs1355695081 1108 dbSNP
rs1466715485 1109 dbSNP
rs917781549 1114 dbSNP
rs992005964 1116 dbSNP
rs1314376092 1125 dbSNP
rs529562958 1126 dbSNP
rs199871601 1127 dbSNP
rs754249310 1127 dbSNP
rs1378972448 1131 dbSNP
rs13065166 1139 dbSNP
rs926370823 1144 dbSNP
rs1312309007 1150 dbSNP
rs1234958400 1154 dbSNP
rs1253822988 1155 dbSNP
rs984432066 1158 dbSNP
rs951715561 1159 dbSNP
rs1026553266 1163 dbSNP
rs994187879 1169 dbSNP
rs1459465201 1170 dbSNP
rs13087748 1172 dbSNP
rs13087746 1174 dbSNP
rs966322444 1178 dbSNP
rs1249904126 1183 dbSNP
rs1433901432 1185 dbSNP
rs777790334 1186 dbSNP
rs1412135461 1194 dbSNP
rs1457809407 1198 dbSNP
rs13065151 1199 dbSNP
rs200310539 1202 dbSNP
rs562907033 1202 dbSNP
rs543052179 1218 dbSNP
rs1171069669 1219 dbSNP
rs770045515 1220 dbSNP
rs1402260645 1221 dbSNP
rs1463975216 1232 dbSNP
rs1297609623 1239 dbSNP
rs1368228385 1253 dbSNP
rs1387933518 1256 dbSNP
rs1019497903 1259 dbSNP
rs1298593934 1281 dbSNP
rs1344418809 1282 dbSNP
rs1218917619 1284 dbSNP
rs1007695814 1290 dbSNP
rs1320526784 1296 dbSNP
rs897219156 1303 dbSNP
rs1251189845 1304 dbSNP
rs544155554 1311 dbSNP
rs13064969 1316 dbSNP
rs1211674498 1318 dbSNP
rs1265388463 1321 dbSNP
rs1475776312 1339 dbSNP
rs150495562 1349 dbSNP
rs1425504935 1350 dbSNP
rs1476753259 1364 dbSNP
rs141728077 1369 dbSNP
rs1350355366 1372 dbSNP
rs1180348901 1376 dbSNP
rs1480319800 1378 dbSNP
rs1000141004 1382 dbSNP
rs867826041 1383 dbSNP
rs1042306313 1390 dbSNP
rs759713367 1397 dbSNP
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rs1294693953 1459 dbSNP
rs781587918 1460 dbSNP
rs930287573 1460 dbSNP
rs1398305763 1463 dbSNP
rs1313633332 1465 dbSNP
rs918956384 1466 dbSNP
rs1240911556 1467 dbSNP
rs1288276572 1471 dbSNP
rs1315324265 1490 dbSNP
rs1215382450 1491 dbSNP
rs971765271 1497 dbSNP
rs1484145571 1503 dbSNP
rs1181537783 1504 dbSNP
rs560431359 1518 dbSNP
rs1440274104 1522 dbSNP
rs1019212518 1526 dbSNP
rs1405226512 1534 dbSNP
rs1399726100 1536 dbSNP
rs986244913 1549 dbSNP
rs1360099258 1555 dbSNP
rs10222515 1556 dbSNP
rs1335175617 1559 dbSNP
rs189956649 1563 dbSNP
rs1448225582 1571 dbSNP
rs779549745 1577 dbSNP
rs1311510797 1582 dbSNP
rs1033052087 1586 dbSNP
rs1371364538 1595 dbSNP
rs185395801 1596 dbSNP
rs1279525313 1597 dbSNP
rs1157160466 1603 dbSNP
rs1000278502 1605 dbSNP
rs903268390 1607 dbSNP
rs1179025226 1609 dbSNP
rs1458141742 1610 dbSNP
rs1180476923 1612 dbSNP
rs34664728 1615 dbSNP
rs1020668597 1616 dbSNP
rs1014268378 1617 dbSNP
rs796600655 1617 dbSNP
rs1191283323 1627 dbSNP
rs1056418151 1632 dbSNP
rs1467923162 1635 dbSNP
rs139278484 1640 dbSNP
rs368271126 1642 dbSNP
rs375118784 1644 dbSNP
rs180734304 1645 dbSNP
rs1466594974 1649 dbSNP
rs546928700 1651 dbSNP
rs867812340 1659 dbSNP
rs1334017764 1663 dbSNP
rs1353283035 1664 dbSNP
rs1468719715 1668 dbSNP
rs571703787 1669 dbSNP
rs1221968952 1688 dbSNP
rs1282364294 1696 dbSNP
rs1318418140 1703 dbSNP
rs1200445104 1706 dbSNP
rs1270732365 1708 dbSNP
rs1437172739 1716 dbSNP
rs749928194 1718 dbSNP
rs1315950124 1719 dbSNP
rs1247996766 1720 dbSNP
rs1307344248 1721 dbSNP
rs561036757 1726 dbSNP
rs1429011095 1738 dbSNP
rs1478320243 1746 dbSNP
rs1170010358 1748 dbSNP
rs919027548 1750 dbSNP
rs1409921324 1755 dbSNP
rs1438092537 1769 dbSNP
rs551543003 1775 dbSNP
rs1403333077 1777 dbSNP
rs1302840112 1780 dbSNP
rs1341381948 1781 dbSNP
rs1268234413 1790 dbSNP
rs1338639716 1792 dbSNP
rs1228857288 1799 dbSNP
rs944411408 1801 dbSNP
rs1489669470 1802 dbSNP
rs912119934 1803 dbSNP
rs1263370785 1809 dbSNP
rs1397051055 1813 dbSNP
rs1489083784 1838 dbSNP
rs1195716612 1841 dbSNP
rs986382516 1842 dbSNP
rs1475357412 1844 dbSNP
rs35755694 1845 dbSNP
rs1164409474 1855 dbSNP
rs1287475870 1858 dbSNP
rs528587590 1859 dbSNP
rs1422762600 1883 dbSNP
rs1163016893 1894 dbSNP
rs1361370950 1902 dbSNP
rs1384180902 1903 dbSNP
rs953545701 1905 dbSNP
rs1325704697 1918 dbSNP
rs1033103066 1921 dbSNP
rs978905978 1926 dbSNP
rs1244548236 1931 dbSNP
rs1161620929 1934 dbSNP
rs1286133619 1940 dbSNP
rs1355379320 1948 dbSNP
rs1203052490 1952 dbSNP
rs1260081784 1963 dbSNP
rs1431463276 1973 dbSNP
rs1188701856 1975 dbSNP
rs967836346 1984 dbSNP
rs1443364046 1988 dbSNP
rs1183015270 1996 dbSNP
rs544464192 1998 dbSNP
rs1381040874 2005 dbSNP
rs1455533715 2012 dbSNP
rs1157102875 2018 dbSNP
rs1394589644 2021 dbSNP
rs1020384128 2024 dbSNP
rs1014650593 2028 dbSNP
rs1192860073 2032 dbSNP
rs1338493557 2034 dbSNP
rs764853650 2036 dbSNP
rs960096389 2045 dbSNP
rs1034927508 2048 dbSNP
rs1309315992 2048 dbSNP
rs1337084570 2054 dbSNP
rs189610545 2060 dbSNP
rs186314847 2061 dbSNP
rs538437164 2061 dbSNP
rs1201351072 2068 dbSNP
rs146948186 2069 dbSNP
rs897552026 2076 dbSNP
rs1238848805 2079 dbSNP
rs1260920831 2084 dbSNP
rs1179754580 2110 dbSNP
rs1363397539 2111 dbSNP
rs1036142819 2115 dbSNP
rs1217521448 2116 dbSNP
rs1178296504 2126 dbSNP
rs944364831 2129 dbSNP
rs1469225259 2133 dbSNP
rs1278994638 2134 dbSNP
rs1332027859 2137 dbSNP
rs181909036 2142 dbSNP
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rs1373828249 2149 dbSNP
rs1331281110 2156 dbSNP
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rs1294112167 2161 dbSNP
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rs1381990180 2165 dbSNP
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rs575691520 2168 dbSNP
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rs988671326 3995 dbSNP
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rs1350323152 4000 dbSNP
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rs934379216 4025 dbSNP
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rs564700156 4680 dbSNP
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rs1028601767 4695 dbSNP
rs1045591788 4697 dbSNP
rs948415133 4706 dbSNP
rs751192056 4717 dbSNP
rs1259142908 4720 dbSNP
rs1423863462 4721 dbSNP
rs995891922 4730 dbSNP
rs915675763 4738 dbSNP
rs866786820 4739 dbSNP
rs1195423312 4742 dbSNP
rs1448392232 4747 dbSNP
rs1285602398 4752 dbSNP
rs1358845239 4754 dbSNP
rs1038419278 4759 dbSNP
rs79515006 4762 dbSNP
rs770411784 4777 dbSNP
rs1484525345 4781 dbSNP
rs1246323913 4783 dbSNP
rs571047437 4785 dbSNP
rs866304650 4792 dbSNP
rs1188425943 4797 dbSNP
rs1239444672 4801 dbSNP
rs188569010 4806 dbSNP
rs534498598 4809 dbSNP
rs1412578512 4811 dbSNP
rs1056223478 4817 dbSNP
rs937888958 4818 dbSNP
rs1231693257 4819 dbSNP
rs182932919 4823 dbSNP
rs1313515730 4824 dbSNP
rs1335732119 4824 dbSNP
rs979350138 4825 dbSNP
rs548221731 4826 dbSNP
rs1351630249 4828 dbSNP
rs1230841194 4835 dbSNP
rs1296427786 4839 dbSNP
rs534158338 4841 dbSNP
rs1011314555 4845 dbSNP
rs1280946152 4848 dbSNP
rs1464861523 4849 dbSNP
rs1209859816 4852 dbSNP
rs913538120 4855 dbSNP
rs1473454055 4857 dbSNP
rs1400801471 4872 dbSNP
rs71304039 4874 dbSNP
rs1173865453 4875 dbSNP
rs1399586023 4878 dbSNP
rs907125660 4879 dbSNP
rs1312646368 4881 dbSNP
rs1045560152 4886 dbSNP
rs114381197 4889 dbSNP
rs894198328 4890 dbSNP
rs1038151156 4892 dbSNP
rs1234018687 4899 dbSNP
rs552081202 4902 dbSNP
rs1345973192 4908 dbSNP
rs908162634 4910 dbSNP
rs113656630 4929 dbSNP
rs1483886244 4933 dbSNP
rs1202800262 4935 dbSNP
rs554783438 4935 dbSNP
rs375290913 4936 dbSNP
rs186302962 4943 dbSNP
rs1260409811 4947 dbSNP
rs1375496169 4950 dbSNP
rs1028925206 4951 dbSNP
rs964211073 4962 dbSNP
rs545794720 4967 dbSNP
rs963296562 4973 dbSNP
rs1285047459 4978 dbSNP
rs1015508238 4979 dbSNP
rs182310051 5008 dbSNP
rs896562806 5009 dbSNP
rs1030966580 5010 dbSNP
rs1056497913 5011 dbSNP
rs759926978 5014 dbSNP
rs1233690952 5018 dbSNP
rs561714452 5027 dbSNP
rs971278687 5027 dbSNP
rs1002717861 5029 dbSNP
rs1247050949 5030 dbSNP
rs904996512 5033 dbSNP
rs1356961283 5035 dbSNP
rs1043960735 5037 dbSNP
rs946617873 5042 dbSNP
rs913861687 5051 dbSNP
rs1052094655 5055 dbSNP
rs944380766 5058 dbSNP
rs1377632283 5061 dbSNP
rs1447334732 5068 dbSNP
rs1168758337 5073 dbSNP
rs1372932291 5078 dbSNP
rs541857211 5082 dbSNP
rs1333115156 5084 dbSNP
rs781092656 5086 dbSNP
rs1440223630 5093 dbSNP
rs911624577 5097 dbSNP
rs142754892 5100 dbSNP
rs1017182843 5102 dbSNP
rs985872518 5104 dbSNP
rs1380814376 5109 dbSNP
rs953259996 5110 dbSNP
rs886872082 5117 dbSNP
rs1271148521 5129 dbSNP
rs576437668 5132 dbSNP
rs921408595 5133 dbSNP
rs1208785920 5134 dbSNP
rs1269536273 5135 dbSNP
rs974649238 5142 dbSNP
rs1185506127 5148 dbSNP
rs1256451649 5152 dbSNP
rs962989215 5154 dbSNP
rs1190098013 5166 dbSNP
rs556666303 5177 dbSNP
rs1361568099 5186 dbSNP
rs1178508228 5194 dbSNP
rs1461434705 5194 dbSNP
rs139271313 5208 dbSNP
rs1046691242 5209 dbSNP
rs1451734067 5212 dbSNP
rs1004151663 5216 dbSNP
rs7645116 5226 dbSNP
rs201427251 5227 dbSNP
rs7612699 5228 dbSNP
rs201371242 5229 dbSNP
rs386668601 5229 dbSNP
rs765236429 5249 dbSNP
rs186523378 5251 dbSNP
rs915371299 5262 dbSNP
rs1228999724 5264 dbSNP
rs990060959 5265 dbSNP
rs762015597 5266 dbSNP
rs924039083 5267 dbSNP
rs146733855 5273 dbSNP
rs1484058223 5278 dbSNP
rs1043566187 5284 dbSNP
rs1255935134 5285 dbSNP
rs57897181 5290 dbSNP
rs1475089442 5296 dbSNP
rs200064365 5298 dbSNP
rs554581594 5304 dbSNP
rs1354292377 5309 dbSNP
rs1410826330 5312 dbSNP
rs1417353630 5316 dbSNP
rs1158522673 5317 dbSNP
rs1311434350 5322 dbSNP
rs892377033 5324 dbSNP
rs143647731 5326 dbSNP
rs764345832 5327 dbSNP
rs944621912 5338 dbSNP
rs1374551549 5339 dbSNP
rs368563954 5341 dbSNP
rs1388167760 5348 dbSNP
rs568847306 5349 dbSNP
rs1290096634 5360 dbSNP
rs958881665 5362 dbSNP
rs1050520884 5366 dbSNP
rs1419817991 5368 dbSNP
rs1301430982 5371 dbSNP
rs1313589978 5375 dbSNP
rs1231543860 5380 dbSNP
rs1279181793 5383 dbSNP
rs1382675040 5389 dbSNP
rs1172340611 5396 dbSNP
rs931709872 5400 dbSNP
rs1206352156 5406 dbSNP
rs1235068871 5417 dbSNP
rs1005817775 5422 dbSNP
rs1176676248 5424 dbSNP
rs920378500 5426 dbSNP
rs1455643232 5430 dbSNP
rs1171944972 5432 dbSNP
rs974259815 5436 dbSNP
rs73185571 5439 dbSNP
rs1201200502 5442 dbSNP
rs908733899 5446 dbSNP
rs982968205 5452 dbSNP
rs960953436 5453 dbSNP
rs868027293 5454 dbSNP
rs1025377950 5464 dbSNP
rs775857939 5465 dbSNP
rs1217405264 5467 dbSNP
rs1438109867 5468 dbSNP
rs997801969 5468 dbSNP
rs1302184023 5473 dbSNP
rs1288030547 5474 dbSNP
rs900888560 5475 dbSNP
rs1217413888 5480 dbSNP
rs1275618384 5482 dbSNP
rs1034990518 5483 dbSNP
rs7644827 5487 dbSNP
rs1191874082 5488 dbSNP
rs1235225231 5491 dbSNP
rs1407045914 5498 dbSNP
rs1169425592 5501 dbSNP
rs566633487 5501 dbSNP
rs1297247140 5502 dbSNP
rs1165338392 5503 dbSNP
rs1396635768 5503 dbSNP
rs1438036514 5503 dbSNP
rs1053933993 5504 dbSNP
rs1365453273 5505 dbSNP
rs1436915822 5508 dbSNP
rs969494451 5512 dbSNP
rs11443749 5513 dbSNP
rs1211884619 5513 dbSNP
rs1214371486 5513 dbSNP
rs1272698267 5513 dbSNP
rs1291180813 5513 dbSNP
rs1337649911 5513 dbSNP
rs1401950963 5513 dbSNP
rs1491080933 5513 dbSNP
rs527322560 5513 dbSNP
rs59310692 5513 dbSNP
rs879011163 5513 dbSNP
rs1315726723 5514 dbSNP
rs1311521459 5515 dbSNP
rs1430436009 5516 dbSNP
rs1294354915 5522 dbSNP
rs1357913861 5525 dbSNP
rs1231926822 5526 dbSNP
rs1217036076 5527 dbSNP
rs1293232853 5529 dbSNP
rs1329883830 5530 dbSNP
rs577391463 5530 dbSNP
rs1282383748 5532 dbSNP
rs1414412158 5539 dbSNP
rs546406459 5545 dbSNP
rs1174646860 5552 dbSNP
rs935521184 5558 dbSNP
rs1474104966 5567 dbSNP
rs1474659824 5577 dbSNP
rs1187066160 5578 dbSNP
rs1423124040 5579 dbSNP
rs759968645 5581 dbSNP
rs1156355174 5583 dbSNP
rs1406778125 5586 dbSNP
rs529923866 5590 dbSNP
rs982226873 5594 dbSNP
rs1489275966 5595 dbSNP
rs1413351963 5597 dbSNP
rs949362175 5606 dbSNP
rs1010719291 5610 dbSNP
rs1241241297 5613 dbSNP
rs991241871 5629 dbSNP
rs892277487 5630 dbSNP
rs1441763102 5638 dbSNP
rs1030851053 5644 dbSNP
rs1201937224 5646 dbSNP
rs774993521 5649 dbSNP
rs1017289497 5654 dbSNP
rs1209926771 5658 dbSNP
rs1315856871 5662 dbSNP
rs1008783102 5663 dbSNP
rs983958825 5664 dbSNP
rs1362647654 5675 dbSNP
rs1478077880 5683 dbSNP
rs1175078284 5687 dbSNP
rs560876319 5700 dbSNP
rs890380012 5703 dbSNP
rs1433217496 5707 dbSNP
rs1025347189 5711 dbSNP
rs1397815189 5712 dbSNP
rs1341770222 5717 dbSNP
rs181206895 5718 dbSNP
rs997854455 5729 dbSNP
rs1305852437 5738 dbSNP
rs965105108 5741 dbSNP
rs552190279 5742 dbSNP
rs1050091557 5756 dbSNP
rs531689512 5759 dbSNP
rs894037795 5763 dbSNP
rs1336745832 5773 dbSNP
rs562742306 5774 dbSNP
rs1451639754 5775 dbSNP
rs1408533900 5776 dbSNP
rs1195005319 5786 dbSNP
rs931674336 5798 dbSNP
rs1054473314 5805 dbSNP
rs1171584486 5810 dbSNP
rs1193392369 5811 dbSNP
rs1373926192 5815 dbSNP
rs114610034 5817 dbSNP
rs1037833180 5818 dbSNP
rs771329141 5820 dbSNP
rs908683836 5822 dbSNP
rs902722272 5825 dbSNP
rs982915935 5827 dbSNP
rs1440361376 5837 dbSNP
rs1296579519 5840 dbSNP
rs939605367 5846 dbSNP
rs928240752 5849 dbSNP
rs748879333 5850 dbSNP
rs1335448691 5858 dbSNP
rs772568458 5864 dbSNP
rs1215008214 5866 dbSNP
rs1270793562 5868 dbSNP
rs1467641938 5874 dbSNP
rs577282091 5884 dbSNP
rs554389405 5886 dbSNP
rs1055116809 5887 dbSNP
rs1022311548 5888 dbSNP
rs1191537426 5889 dbSNP
rs942057319 5892 dbSNP
rs1475859068 5898 dbSNP
rs1167743210 5906 dbSNP
rs909794794 5913 dbSNP
rs1461009025 5918 dbSNP
rs989532784 5925 dbSNP
rs1257204165 5927 dbSNP
rs190116740 5928 dbSNP
rs1030799072 5939 dbSNP
rs868155444 5944 dbSNP
rs1319524071 5954 dbSNP
rs1356001428 5956 dbSNP
rs575204467 5957 dbSNP
rs555340749 5971 dbSNP
rs746199360 5975 dbSNP
rs1234985844 5977 dbSNP
rs890369356 5979 dbSNP
rs1029352986 5997 dbSNP
rs996127270 5998 dbSNP
rs1484717141 6000 dbSNP
rs918382982 6003 dbSNP
rs1262837401 6006 dbSNP
rs1486211560 6007 dbSNP
rs898797675 6009 dbSNP
rs747752119 6011 dbSNP
rs1037380366 6016 dbSNP
rs139788111 6022 dbSNP
rs1159990623 6036 dbSNP
rs886230874 6042 dbSNP
rs965073585 6048 dbSNP
rs1047212861 6071 dbSNP
rs1375771172 6079 dbSNP
rs1416411586 6086 dbSNP
rs568791516 6087 dbSNP
rs1223831121 6088 dbSNP
rs774748477 6088 dbSNP
rs1032592177 6093 dbSNP
rs1376890505 6094 dbSNP
rs570680876 6094 dbSNP
rs1237809285 6103 dbSNP
rs1280630669 6104 dbSNP
rs1332456236 6114 dbSNP
rs1000146850 6121 dbSNP
rs771398907 6131 dbSNP
rs1467546894 6132 dbSNP
rs1256002278 6138 dbSNP
rs142523556 6144 dbSNP
rs1164371219 6147 dbSNP
rs902781185 6148 dbSNP
rs928222118 6151 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Article - Grimson A; Farh KK; Johnston WK; et al.
- Molecular cell, 2007
Mammalian microRNAs (miRNAs) pair to 3'UTRs of mRNAs to direct their posttranscriptional repression. Important for target recognition are approximately 7 nt sites that match the seed region of the miRNA. However, these seed matches are not always sufficient for repression, indicating that other characteristics help specify targeting. By combining computational and experimental approaches, we uncovered five general features of site context that boost site efficacy: AU-rich nucleotide composition near the site, proximity to sites for coexpressed miRNAs (which leads to cooperative action), proximity to residues pairing to miRNA nucleotides 13-16, positioning within the 3'UTR at least 15 nt from the stop codon, and positioning away from the center of long UTRs. A model combining these context determinants quantitatively predicts site performance both for exogenously added miRNAs and for endogenous miRNA-message interactions. Because it predicts site efficacy without recourse to evolutionary conservation, the model also identifies effective nonconserved sites and siRNA off-targets.
LinkOut: [PMID: 17612493]
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer 0.66 2.2e-4 0.668 1.8e-4 24 Click to see details
GSE27834 Pluripotent stem cells 0.638 3.9e-3 0.574 1.0e-2 16 Click to see details
GSE42095 Differentiated embryonic stem cells 0.5 7.6e-3 0.475 1.1e-2 23 Click to see details
GSE21687 Ependynoma primary tumors 0.17 9.0e-2 0.270 1.5e-2 64 Click to see details
GSE32688 Pancreatic cancer -0.224 1.1e-1 -0.266 7.1e-2 32 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.212 1.5e-1 -0.117 2.9e-1 25 Click to see details
GSE14794 Lymphoblastoid cells 0.101 1.7e-1 0.136 1.0e-1 90 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.431 2.0e-1 0.429 2.0e-1 6 Click to see details
GSE19350 CNS germ cell tumors -0.104 3.7e-1 0.122 3.5e-1 12 Click to see details
GSE26953 Aortic valvular endothelial cells 0.063 3.8e-1 0.073 3.7e-1 24 Click to see details
GSE17306 Multiple myeloma 0.04 3.9e-1 0.110 2.3e-1 49 Click to see details
GSE21849 B cell lymphoma 0.042 4.1e-1 0.064 3.7e-1 29 Click to see details
GSE38226 Liver fibrosis 0.027 4.5e-1 -0.001 5.0e-1 21 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.022 4.6e-1 0.161 2.2e-1 25 Click to see details
GSE28260 Renal cortex and medulla 0.019 4.8e-1 -0.038 4.5e-1 13 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.006 4.9e-1 -0.227 1.7e-1 20 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA 0.948 0.01 0.600 0.14 5 Click to see details
KIRC 0.338 0.04 0.373 0.02 29 Click to see details
ESCA -0.819 0.04 -0.700 0.09 5 Click to see details
STAD 0.514 0.1 0.500 0.1 8 Click to see details
KIRP 0.161 0.34 0.250 0.26 9 Click to see details
LIHC 0.058 0.35 0.000 0.5 49 Click to see details
KICH 0.144 0.37 0.024 0.48 8 Click to see details
CHOL 0.025 0.47 0.083 0.42 9 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
HNSC 0.004 0.5 -0.500 0.33 3 Click to see details
MiRNA Regulatory Network:
Functional analysis: