pre-miRNA Information | |
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pre-miRNA | hsa-mir-15a |
Genomic Coordinates | chr13: 50049119 - 50049201 |
Synonyms | MIRN15A, hsa-mir-15a, miRNA15A, MIR15A |
Description | Homo sapiens miR-15a stem-loop |
Comment | Reference . |
RNA Secondary Structure | ![]() |
Associated Diseases | ![]() |
Mature miRNA Information | |
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Mature miRNA | hsa-miR-15a-5p |
Sequence | 14| UAGCAGCACAUAAUGGUUUGUG |35 |
Evidence | Experimental |
Experiments | Cloned |
SNPs in miRNA | |
Putative Targets |
miRNA Expression profile | |
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Human miRNA Tissue Atlas | |
miRNAs in Extracellular Vesicles |
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Circulating MicroRNA Expression Profiling | Circulating MicroRNA Expression Profiling |
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Gene Information | |||||||||||||||||||||
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Gene Symbol | VEGFA | ||||||||||||||||||||
Synonyms | MVCD1, VEGF, VPF | ||||||||||||||||||||
Description | vascular endothelial growth factor A | ||||||||||||||||||||
Transcript | NM_001025369 | ||||||||||||||||||||
Other Transcripts | NM_001025367 , NM_001025368 , NM_001025366 , NM_001025370 , NM_001033756 , NM_001171622 , NM_001171623 , NM_001171624 , NM_001171625 , NM_001171626 , NM_001171627 , NM_001171628 , NM_001171629 , NM_001171630 , NM_003376 | ||||||||||||||||||||
Expression | |||||||||||||||||||||
Putative miRNA Targets on VEGFA | |||||||||||||||||||||
3'UTR of VEGFA (miRNA target sites are highlighted) |
>VEGFA|NM_001025369|3'UTR 1 CAAGCCGAGGCGGTGAGCCGGGCAGGAGGAAGGAGCCTCCCTCAGGGTTTCGGGAACCAGATCTCTCACCAGGAAAGACT 81 GATACAGAACGATCGATACAGAAACCACGCTGCCGCCACCACACCATCACCATCGACAGAACAGTCCTTAATCCAGAAAC 161 CTGAAATGAAGGAAGAGGAGACTCTGCGCAGAGCACTTTGGGTCCGGAGGGCGAGACTCCGGCGGAAGCATTCCCGGGCG 241 GGTGACCCAGCACGGTCCCTCTTGGAATTGGATTCGCCATTTTATTTTTCTTGCTGCTAAATCACCGAGCCCGGAAGATT 321 AGAGAGTTTTATTTCTGGGATTCCTGTAGACACACCCACCCACATACATACATTTATATATATATATATTATATATATAT 401 AAAAATAAATATCTCTATTTTATATATATAAAATATATATATTCTTTTTTTAAATTAACAGTGCTAATGTTATTGGTGTC 481 TTCACTGGATGTATTTGACTGCTGTGGACTTGAGTTGGGAGGGGAATGTTCCCACTCAGATCCTGACAGGGAAGAGGAGG 561 AGATGAGAGACTCTGGCATGATCTTTTTTTTGTCCCACTTGGTGGGGCCAGGGTCCTCTCCCCTGCCCAGGAATGTGCAA 641 GGCCAGGGCATGGGGGCAAATATGACCCAGTTTTGGGAACACCGACAAACCCAGCCCTGGCGCTGAGCCTCTCTACCCCA 721 GGTCAGACGGACAGAAAGACAGATCACAGGTACAGGGATGAGGACACCGGCTCTGACCAGGAGTTTGGGGAGCTTCAGGA 801 CATTGCTGTGCTTTGGGGATTCCCTCCACATGCTGCACGCGCATCTCGCCCCCAGGGGCACTGCCTGGAAGATTCAGGAG 881 CCTGGGCGGCCTTCGCTTACTCTCACCTGCTTCTGAGTTGCCCAGGAGACCACTGGCAGATGTCCCGGCGAAGAGAAGAG 961 ACACATTGTTGGAAGAAGCAGCCCATGACAGCTCCCCTTCCTGGGACTCGCCCTCATCCTCTTCCTGCTCCCCTTCCTGG 1041 GGTGCAGCCTAAAAGGACCTATGTCCTCACACCATTGAAACCACTAGTTCTGTCCCCCCAGGAGACCTGGTTGTGTGTGT 1121 GTGAGTGGTTGACCTTCCTCCATCCCCTGGTCCTTCCCTTCCCTTCCCGAGGCACAGAGAGACAGGGCAGGATCCACGTG 1201 CCCATTGTGGAGGCAGAGAAAAGAGAAAGTGTTTTATATACGGTACTTATTTAATATCCCTTTTTAATTAGAAATTAAAA 1281 CAGTTAATTTAATTAAAGAGTAGGGTTTTTTTTCAGTATTCTTGGTTAATATTTAATTTCAACTATTTATGAGATGTATC 1361 TTTTGCTCTCTCTTGCTCTCTTATTTGTACCGGTTTTTGTATATAAAATTCATGTTTCCAATCTCTCTCTCCCTGATCGG 1441 TGACAGTCACTAGCTTATCTTGAACAGATATTTAATTTTGCTAACACTCAGCTCTGCCCTCCCCGATCCCCTGGCTCCCC 1521 AGCACACATTCCTTTGAAATAAGGTTTCAATATACATCTACATACTATATATATATTTGGCAACTTGTATTTGTGTGTAT 1601 ATATATATATATATGTTTATGTATATATGTGATTCTGATAAAATAGACATTGCTATTCTGTTTTTTATATGTAAAAACAA 1681 AACAAGAAAAAATAGAGAATTCTACATACTAAATCTCTCTCCTTTTTTAATTTTAATATTTGTTATCATTTATTTATTGG 1761 TGCTACTGTTTATCCGTAATAATTGTGGGGAAAAGATATTAACATCACGTCTTTGTCTCTAGTGCAGTTTTTCGAGATAT 1841 TCCGTAGTACATATTTATTTTTAAACAACGACAAAGAAATACAGATATATCTTAAAAAAAAAAAAGCATTTTGTATTAAA 1921 GAATTTAATTCTGATCTCAAAAAAAAAAAAAAAAAA Target sites
Provided by authors
Predicted by miRanda
DRVs
SNPs
DRVs & SNPs
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miRNA-target interactions (Predicted by miRanda) |
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DRVs in gene 3'UTRs | |||||||||||||||||||
SNPs in gene 3'UTRs |
Experimental Support 1 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
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Conditions | Cos-7 |
Location of target site | 3'UTR |
Tools used in this research | FindTar |
Original Description (Extracted from the article) |
...
{This MTI is shown in Fig. 1 and Fig. 2}
... - Ye W; Lv Q; Wong CK; Hu S; Fu C; Hua Z; Cai et al., 2008, PloS one. |
Article |
- Ye W; Lv Q; Wong CK; Hu S; Fu C; Hua Z; Cai et al. - PloS one, 2008
MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent research, the importance of the 5' end of the miRNA:MRE duplex has been emphasized and the effect of the tail region addressed, but the role of the central loop has largely remained unexplored. Here we examined the effect of the loop region in miRNA:MRE duplexes and found that the location of the central loop is one of the important factors affecting the efficiency of gene regulation mediated by miRNAs. It was further determined that the addition of a loop score combining both location and size as a new criterion for predicting MREs and their cognate miRNAs significantly decreased the false positive rates and increased the specificity of MRE prediction.
LinkOut: [PMID: 18320040]
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Experimental Support 2 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | HEK293 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control
PAR-CLIP data was present in GSM545213. RNA binding protein: AGO2. Condition:Control
PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control
PAR-CLIP data was present in GSM545215. RNA binding protein: AGO4. Condition:Control
PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection
PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection
... - Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell. |
Article |
- Hafner M; Landthaler M; Burger L; Khorshid et al. - Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
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Experimental Support 3 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | HEK293 |
Disease | 7422.0 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
"HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1
"HITS-CLIP data was present in GSM714643. RNA binding protein: AGO2. Condition:completeT1
"PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1
... - Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods. |
Article |
- Kishore S; Jaskiewicz L; Burger L; Hausser et al. - Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
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Experimental Support 4 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | hESCs (WA-09) |
Disease | 7422.0 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
"PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine
... - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development. |
Article |
- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al. - Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
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Experimental Support 5 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | Jiyoye |
Tools used in this research | TargetScan |
Original Description (Extracted from the article) |
...
HITS-CLIP data was present in Supplenentary. RNA binding protein: AGO2.
... - Riley KJ; Rabinowitz GS; Yario TA; Luna JM; et al., 2012, The EMBO journal. |
Article |
- Riley KJ; Rabinowitz GS; Yario TA; Luna JM; et al. - The EMBO journal, 2012
Epstein-Barr virus (EBV) controls gene expression to transform human B cells and maintain viral latency. High-throughput sequencing and crosslinking immunoprecipitation (HITS-CLIP) identified mRNA targets of 44 EBV and 310 human microRNAs (miRNAs) in Jijoye (Latency III) EBV-transformed B cells. While 25% of total cellular miRNAs are viral, only three viral mRNAs, all latent transcripts, are targeted. Thus, miRNAs do not control the latent/lytic switch by targeting EBV lytic genes. Unexpectedly, 90% of the 1664 human 3'-untranslated regions targeted by the 12 most abundant EBV miRNAs are also targeted by human miRNAs via distinct binding sites. Half of these are targets of the oncogenic miR-17 approximately 92 miRNA cluster and associated families, including mRNAs that regulate transcription, apoptosis, Wnt signalling, and the cell cycle. Reporter assays confirmed the functionality of several EBV and miR-17 family miRNA-binding sites in EBV latent membrane protein 1 (LMP1), EBV BHRF1, and host CAPRIN2 mRNAs. Our extensive list of EBV and human miRNA targets implicates miRNAs in the control of EBV latency and illuminates viral miRNA function in general.
LinkOut: [PMID: 22473208]
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Experimental Support 6 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | RPMI-8226 , ARH-77 , OPM-2 , U266 |
Location of target site | 3'UTR |
Tools used in this research | microRNA.org , TargetRank , TargetScan |
Original Description (Extracted from the article) |
...
Western blotting combined with the luciferase reporter assay demonstrated that VEGF-A was a direct target of miR-15a/16.
... - Sun CY; She XM; Qin Y; Chu ZB; Chen L; Ai et al., 2013, Carcinogenesis. |
Article |
- Sun CY; She XM; Qin Y; Chu ZB; Chen L; Ai et al. - Carcinogenesis, 2013
Deregulated microRNAs (miRNAs) and their roles in cancer development have attracted much attention. Two miRNAs, miR-15a and miR-16, which act as putative tumor suppressor by targeting the oncogene BCL2, have been implicated in cell cycle, apoptosis and proliferation. In this study, we investigated the possible role of miR-15a/16 in the angiogenesis of multiple myeloma (MM). Using a stem-loop quantitative reverse transcription-PCR, we analyzed miR-15a/16 expressions in bone marrow samples from newly diagnosed MM patients and a panel of MM cell lines. miRNA transfection, western blotting analysis and assay of luciferase activity were used to examine whether vascular endothelial growth factor (VEGF) is the target of miR-15a/16. The functional roles of miR-15a/16 on tumorigenesis and angiogenesis were examined by in vitro angiogenesis models and in vivo tumor xenograft model. We showed that miR-15a and miR-16 were significantly underexpressed in primary MM cells as well as in MM cell lines. The aberrant expression of miR-15a/16 was detected especially in advanced stage MM. In human MM cell lines and normal plasma cells, expression of miR-15a/16 inversely correlated with the expression of VEGF-A. Western blotting combined with the luciferase reporter assay demonstrated that VEGF-A was a direct target of miR-15a/16. Ectopic overexpression of miR-15a/16 led to decreased pro-angiogenic activity of MM cells. Finally, infection of lentivirus-miR-15a or lentivirus-miR-16 resulted in significant inhibition of tumor growth and angiogenesis in nude mice. This study suggest that miR-15a/16 could play a role in the tumorigenesis of MM at least in part by modulation of angiogenesis through targeting VEGF-A.
LinkOut: [PMID: 23104180]
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Experimental Support 7 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | PACs |
Location of target site | 3'UTR |
Tools used in this research | TargetScan |
Original Description (Extracted from the article) |
...
VEGF-A and AKT3 Are Direct Targets of Both miR-15a and miR-16
... - Spinetti G; Fortunato O; Caporali A; et al., 2013, Circulation research. |
Article |
- Spinetti G; Fortunato O; Caporali A; et al. - Circulation research, 2013
RATIONALE: Circulating proangiogenic cells (PACs) support postischemic neovascularization. Cardiovascular disease and diabetes mellitus impair PAC regenerative capacities via molecular mechanisms that are not fully known. We hypothesize a role for microRNAs (miRs). Circulating miRs are currently investigated as potential diagnostic and prognostic biomarkers. OBJECTIVE: The objectives were the following: (1) to profile miR expression in PACs from critical limb ischemia (CLI) patients; (2) to demonstrate that miR-15a and miR-16 regulate PAC functions; and (3) to characterize circulating miR-15a and miR-16 and to investigate their potential biomarker value. METHODS AND RESULTS: Twenty-eight miRs potentially able to modulate angiogenesis were measured in PACs from CLI patients with and without diabetes mellitus and controls. miR-15a and miR-16 were further analyzed. CLI-PACs expressed higher level of mature miR-15a and miR-16 and of the primary transcript pri-miR-15a/16-1. miR-15a/16 overexpression impaired healthy PAC survival and migration. Conversely, miR-15a/16 inhibition improved CLI-PAC-defective migration. Vascular endothelial growth factor-A and AKT-3 were validated as direct targets of the 2 miRs, and their protein levels were reduced in miR-15a/16-overexpressing healthy PACs and in CLI-PACs. Transplantation of healthy PACs ex vivo-engineered with anti-miR-15a/16 improved postischemic blood flow recovery and muscular arteriole density in immunodeficient mice. miR-15a and miR-16 were present in human blood, including conjugated to argonaute-2 and in exosomes. Both miRs were increased in the serum of CLI patients and positively correlated with amputation after restenosis at 12 months postrevascularization of CLI type 2 diabetes mellitus patients. Serum miR-15a additionally correlated with restenosis at follow-up. CONCLUSIONS: Ex vivo miR-15a/16 inhibition enhances PAC therapeutic potential, and circulating miR-15a and miR-16 deserves further investigation as a prognostic biomarker in CLI patients undergoing revascularization.
LinkOut: [PMID: 23233752]
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Experimental Support 8 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | HEK293 |
Disease | 7422.0 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
"PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine
"PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine
"PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine
... - Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature. |
Article |
- Memczak S; Jens M; Elefsinioti A; Torti F; et al. - Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
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Experimental Support 9 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | C8166 , TZM-bl |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in GSM1462572. RNA binding protein: AGO2. Condition:C8166 NL4-3
PAR-CLIP data was present in GSM1462573. RNA binding protein: AGO2. Condition:TZM-bl BaL
PAR-CLIP data was present in GSM1462574. RNA binding protein: AGO2. Condition:TZM-bl ami BaL
... - Whisnant AW; Bogerd HP; Flores O; Ho P; et al., 2013, mBio. |
Article |
- Whisnant AW; Bogerd HP; Flores O; Ho P; et al. - mBio, 2013
UNLABELLED: The question of how HIV-1 interfaces with cellular microRNA (miRNA) biogenesis and effector mechanisms has been highly controversial. Here, we first used deep sequencing of small RNAs present in two different infected cell lines (TZM-bl and C8166) and two types of primary human cells (CD4(+) peripheral blood mononuclear cells [PBMCs] and macrophages) to unequivocally demonstrate that HIV-1 does not encode any viral miRNAs. Perhaps surprisingly, we also observed that infection of T cells by HIV-1 has only a modest effect on the expression of cellular miRNAs at early times after infection. Comprehensive analysis of miRNA binding to the HIV-1 genome using the photoactivatable ribonucleoside-induced cross-linking and immunoprecipitation (PAR-CLIP) technique revealed several binding sites for cellular miRNAs, a subset of which were shown to be capable of mediating miRNA-mediated repression of gene expression. However, the main finding from this analysis is that HIV-1 transcripts are largely refractory to miRNA binding, most probably due to extensive viral RNA secondary structure. Together, these data demonstrate that HIV-1 neither encodes viral miRNAs nor strongly influences cellular miRNA expression, at least early after infection, and imply that HIV-1 transcripts have evolved to avoid inhibition by preexisting cellular miRNAs by adopting extensive RNA secondary structures that occlude most potential miRNA binding sites. IMPORTANCE: MicroRNAs (miRNAs) are a ubiquitous class of small regulatory RNAs that serve as posttranscriptional regulators of gene expression. Previous work has suggested that HIV-1 might subvert the function of the cellular miRNA machinery by expressing viral miRNAs or by dramatically altering the level of cellular miRNA expression. Using very sensitive approaches, we now demonstrate that neither of these ideas is in fact correct. Moreover, HIV-1 transcripts appear to largely avoid regulation by cellular miRNAs by adopting an extensive RNA secondary structure that occludes the ability of cellular miRNAs to interact with viral mRNAs. Together, these data suggest that HIV-1, rather than seeking to control miRNA function in infected cells, has instead evolved a mechanism to become largely invisible to cellular miRNA effector mechanisms.
LinkOut: [PMID: 23592263]
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Experimental Support 10 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | MCF7 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated
... - Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology. |
Article |
- Farazi TA; Ten Hoeve JJ; Brown M; et al. - Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
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Experimental Support 11 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | DU145 , HUVEC |
Disease | MIMAT0000068 |
Location of target site | 3'UTR |
Tools used in this research | DIANA-microT , miRanda , miRBase Target Database , miRWALK , PicTar , TargetScan |
Original Description (Extracted from the article) |
...
"The luciferase assays showed that compared with control
... - Terzuoli E; Donnini S; Finetti F; Nesi G; et al., 2016, Oncotarget. |
Article |
- Terzuoli E; Donnini S; Finetti F; Nesi G; et al. - Oncotarget, 2016
Prostaglandin E-2 (PGE-2) promotes tumor angiogenesis via paracrine secretion of pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF). Since miRNAs regulate several cell processes, including angiogenesis, we sought to determine whether they would influence PGE-2-induced VEGF. We compared DU145 and PC3 prostate cancer cells bearing the mPGES-1 enzyme (mPGES-1+/+) and producing PGE-2, with those in which the enzyme was silenced or deleted (mPGES-1-/-). We demonstrated that mPGES-1/PGE-2 signaling decreased Dicer expression and miRNA biogenesis. Genome-wide sequencing of miRNAs revealed that miR-15a and miR-186, associated with expression of VEGF and hypoxia inducible factor-1alpha (HIF-1alpha), were down-regulated in mPGES-1+/+ cells. As a consequence, mPGES-1+/+ tumor cells expressed high levels of VEGF and HIF-1alpha, induced endothelial cells activation and formed highly vascularized tumors. Mir-186 mimic inhibited VEGF expression in mPGES-1+/+ tumor xenografts and reduced tumor growth. In human prostate cancer specimens, mPGES-1 was over-expressed in tumors with high Gleason score, elevated expression of VEGF and HIF-1alpha, high microvessel density and decreased expression of Dicer, miR15a and miR-186. Thus, clear evidence for regulating miRNA processing and VEGF output by intrinsic PGE-2 production provides a means to distinguish between aggressive and indolent prostate tumors and suggests a potential target for controlling tumor progression.
LinkOut: [PMID: 27322147]
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Experimental Support 12 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
|
Conditions | HEK293T |
Disease | osteoarthritis |
Location of target site | 3'UTR |
Tools used in this research | miRDB , TargetScan |
Original Description (Extracted from the article) |
...
miR-15a-5p contributes to cell apoptosis and matrix degradation via inhibiting VEGFA//miR-15a-5p regulates viability and matrix degradation of OA and induced a new target for OA diagnosis and therapy
... - Chen H; Tian Y, 2017, Bioscience trends. |
Article |
- Chen H; Tian Y - Bioscience trends, 2017
Previous studies demonstrated that miR-15a-5p was probably associated with human hepatocellular carcinoma, while the function of miR-15a-5p in OA (Osteoarthritis) still remains unknown. Here, we uncovered the potential role of miR-15a-5p on OA pathogenesis and confirmed its predicted target VEGFA (Vascular Endothelial Growth Factor A). Measured by RT-PCR, miR-15a-5p expression increased remarkably while VEGFA expression was significantly decreased in OA chondrocytes compared with normal conditions. According to Luciferase activity assay, miR-15a-5p directly targeted the 3'-UTR of VEGFA to inhibit its expression. Functional analysis including CCK-8 assay and flow cytometry revealed that overexpression of VEGFA or inhibition of miR-15a-5p promoted cell proliferation, suppressed cell apoptosis and reduced matrix degradation in OA chondrocytes. Moreover, rescue assays carried out with both expression of VEGFA and miR-15a-5p demonstrated that miR-15a-5p contributes to cell apoptosis and matrix degradation via inhibiting VEGFA. We further provided evidence that multiple proteins related to matrix synthesis were regulated by miR-15a-5p and VEGFA using Western blot and ELISA assays. Taken together, our findings elucidated an underlying mechanism by which miR-15a-5p regulates viability and matrix degradation of OA and indicated a new target for OA diagnosis and therapy.
LinkOut: [PMID: 27916780]
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CLIP-seq Support 1 for dataset GSM714642 | |
Method / RBP | HITS-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / completeT1, repA |
Location of target site | ENST00000372067.3 | 3UTR | GCCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 21572407 / GSE28865 |
CLIP-seq Viewer | Link |
CLIP-seq Support 2 for dataset GSM714643 | |
Method / RBP | HITS-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / completeT1, repB |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCGAGCCCGG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 21572407 / GSE28865 |
CLIP-seq Viewer | Link |
CLIP-seq Support 3 for dataset GSM545212 | |
Method / RBP | PAR-CLIP / AGO1 |
---|---|
Cell line / Condition | HEK293 / Control |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCGA |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 4 for dataset GSM545213 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / Control |
Location of target site | ENST00000372067.3 | 3UTR | UAUUUUUCUUGCUGC |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 5 for dataset GSM545214 | |
Method / RBP | PAR-CLIP / AGO3 |
---|---|
Cell line / Condition | HEK293 / Control |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCA |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 6 for dataset GSM545215 | |
Method / RBP | PAR-CLIP / AGO4 |
---|---|
Cell line / Condition | HEK293 / Control |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUC |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 7 for dataset GSM545216 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / miR-124 transfection |
Location of target site | ENST00000372067.3 | 3UTR | AUUCGCCAUUUUAUUUUUCUUGCUGCUAAAUCACCGA |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 8 for dataset GSM545217 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / miR-7 transfection |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCGA |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 20371350 / GSE21578 |
CLIP-seq Viewer | Link |
CLIP-seq Support 9 for dataset GSM714645 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / completeT1, repB |
Location of target site | ENST00000372067.3 | 3UTR | CGCCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 21572407 / GSE28865 |
CLIP-seq Viewer | Link |
CLIP-seq Support 10 for dataset SRR359787 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | hESCs (WA-09) / 4-thiouridine, RNase T1 |
Location of target site | ENST00000372067.3 | 3UTR | AUUCGCCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 22012620 / SRX103431 |
CLIP-seq Viewer | Link |
CLIP-seq Support 11 for dataset GSM1065668 | |
Method / RBP | PAR-CLIP / AGO1 |
---|---|
Cell line / Condition | HEK293 / 4-thiouridine, ML_MM_7 |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACC |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23446348 / GSE43573 |
CLIP-seq Viewer | Link |
CLIP-seq Support 12 for dataset GSM1065669 | |
Method / RBP | PAR-CLIP / AGO1 |
---|---|
Cell line / Condition | HEK293 / 4-thiouridine, ML_MM_8 |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23446348 / GSE43573 |
CLIP-seq Viewer | Link |
CLIP-seq Support 13 for dataset GSM1065670 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | HEK293 / 4-thiouridine, 3_ML_LG |
Location of target site | ENST00000372067.3 | 3UTR | AUUCGCCAUUUUAUUUUUCUUGCUGCUAAAUCACC |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23446348 / GSE43573 |
CLIP-seq Viewer | Link |
CLIP-seq Support 14 for dataset SRR1045082 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | MCF7 / Untreated |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 24398324 / SRX388831 |
CLIP-seq Viewer | Link |
CLIP-seq Support 15 for dataset GSM1462572 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | C8166 / C8166 NL4-3 |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23592263 / GSE59944 |
CLIP-seq Viewer | Link |
CLIP-seq Support 16 for dataset GSM1462573 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | TZM-bl / TZM-bl BaL |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23592263 / GSE59944 |
CLIP-seq Viewer | Link |
CLIP-seq Support 17 for dataset GSM1462574 | |
Method / RBP | PAR-CLIP / AGO2 |
---|---|
Cell line / Condition | TZM-bl / TZM-bl ami BaL |
Location of target site | ENST00000372067.3 | 3UTR | CCAUUUUAUUUUUCUUGCUGCUAAAUCACCG |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 23592263 / GSE59944 |
CLIP-seq Viewer | Link |
MiRNA-Target Expression Profile | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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MiRNA-Target Expression Profile (TCGA) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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|
ID![]() |
Target | Description | Validation methods |
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Strong evidence | Less strong evidence | |||||||||||
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MIRT736201 | DRD1 | dopamine receptor D1 | ![]() |
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3 | 0 | |||||
MIRT735131 | GSDMB | gasdermin B | ![]() |
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2 | 0 | ||||||
MIRT731341 | CXCL10 | C-X-C motif chemokine ligand 10 | ![]() |
1 | 1 | |||||||
MIRT728400 | ACOX1 | acyl-CoA oxidase 1 | ![]() |
1 | 1 | |||||||
MIRT728384 | AFF4 | AF4/FMR2 family member 4 | ![]() |
1 | 1 | |||||||
MIRT728330 | AP3M1 | adaptor related protein complex 3 mu 1 subunit | ![]() |
1 | 1 | |||||||
MIRT728290 | ASXL1 | additional sex combs like 1, transcriptional regulator | ![]() |
1 | 1 | |||||||
MIRT728265 | ATP13A3 | ATPase 13A3 | ![]() |
1 | 1 | |||||||
MIRT728237 | B4GALT1 | beta-1,4-galactosyltransferase 1 | ![]() |
1 | 1 | |||||||
MIRT728194 | BSG | basigin (Ok blood group) | ![]() |
1 | 1 | |||||||
MIRT728133 | C15orf39 | chromosome 15 open reading frame 39 | ![]() |
1 | 1 | |||||||
MIRT728127 | LRIF1 | ligand dependent nuclear receptor interacting factor 1 | ![]() |
1 | 1 | |||||||
MIRT728101 | C2orf42 | chromosome 2 open reading frame 42 | ![]() |
1 | 1 | |||||||
MIRT728092 | C6orf106 | chromosome 6 open reading frame 106 | ![]() |
1 | 1 | |||||||
MIRT728047 | CBFA2T3 | CBFA2/RUNX1 translocation partner 3 | ![]() |
1 | 1 | |||||||
MIRT728019 | CDC27 | cell division cycle 27 | ![]() |
1 | 1 | |||||||
MIRT728006 | CDKN2AIPNL | CDKN2A interacting protein N-terminal like | ![]() |
1 | 1 | |||||||
MIRT727999 | RHOV | ras homolog family member V | ![]() |
1 | 1 | |||||||
MIRT727953 | CPNE1 | copine 1 | ![]() |
1 | 1 | |||||||
MIRT727936 | CREG1 | cellular repressor of E1A stimulated genes 1 | ![]() |
1 | 1 | |||||||
MIRT727924 | CSDE1 | cold shock domain containing E1 | ![]() |
1 | 1 | |||||||
MIRT727917 | CUL2 | cullin 2 | ![]() |
1 | 1 | |||||||
MIRT727913 | CYB561A3 | cytochrome b561 family member A3 | ![]() |
1 | 1 | |||||||
MIRT727910 | CYLD | CYLD lysine 63 deubiquitinase | ![]() |
1 | 1 | |||||||
MIRT727876 | DICER1 | dicer 1, ribonuclease III | ![]() |
1 | 1 | |||||||
MIRT727866 | DNAJC9 | DnaJ heat shock protein family (Hsp40) member C9 | ![]() |
1 | 1 | |||||||
MIRT727860 | DPP8 | dipeptidyl peptidase 8 | ![]() |
1 | 1 | |||||||
MIRT727856 | DSCR3 | DSCR3 arrestin fold containing | ![]() |
1 | 1 | |||||||
MIRT727814 | EDC3 | enhancer of mRNA decapping 3 | ![]() |
1 | 1 | |||||||
MIRT727719 | AMER1 | APC membrane recruitment protein 1 | ![]() |
1 | 1 | |||||||
MIRT727701 | FAM73A | mitoguardin 1 | ![]() |
1 | 1 | |||||||
MIRT727647 | FRYL | FRY like transcription coactivator | ![]() |
1 | 1 | |||||||
MIRT727619 | GABARAP | GABA type A receptor-associated protein | ![]() |
1 | 1 | |||||||
MIRT727605 | GANAB | glucosidase II alpha subunit | ![]() |
1 | 1 | |||||||
MIRT727585 | GGA3 | golgi associated, gamma adaptin ear containing, ARF binding protein 3 | ![]() |
1 | 1 | |||||||
MIRT727523 | GSK3B | glycogen synthase kinase 3 beta | ![]() |
1 | 1 | |||||||
MIRT727483 | HYOU1 | hypoxia up-regulated 1 | ![]() |
1 | 1 | |||||||
MIRT727426 | IRAK1BP1 | interleukin 1 receptor associated kinase 1 binding protein 1 | ![]() |
1 | 1 | |||||||
MIRT727385 | KATNAL1 | katanin catalytic subunit A1 like 1 | ![]() |
1 | 1 | |||||||
MIRT727377 | TECPR2 | tectonin beta-propeller repeat containing 2 | ![]() |
1 | 1 | |||||||
MIRT727349 | KLC2 | kinesin light chain 2 | ![]() |
1 | 1 | |||||||
MIRT727297 | LITAF | lipopolysaccharide induced TNF factor | ![]() |
1 | 1 | |||||||
MIRT727271 | LRPPRC | leucine rich pentatricopeptide repeat containing | ![]() |
1 | 1 | |||||||
MIRT727268 | LRRC57 | leucine rich repeat containing 57 | ![]() |
1 | 1 | |||||||
MIRT727262 | LYRM5 | electron transfer flavoprotein regulatory factor 1 | ![]() |
1 | 1 | |||||||
MIRT727228 | MCM3AP-AS1 | MCM3AP antisense RNA 1 | ![]() |
1 | 1 | |||||||
MIRT727223 | MED11 | mediator complex subunit 11 | ![]() |
1 | 1 | |||||||
MIRT727198 | MIB1 | mindbomb E3 ubiquitin protein ligase 1 | ![]() |
1 | 1 | |||||||
MIRT727176 | MLXIP | MLX interacting protein | ![]() |
1 | 1 | |||||||
MIRT727154 | MRPL40 | mitochondrial ribosomal protein L40 | ![]() |
1 | 1 | |||||||
MIRT727137 | MTMR4 | myotubularin related protein 4 | ![]() |
1 | 1 | |||||||
MIRT727096 | NCOR2 | nuclear receptor corepressor 2 | ![]() |
1 | 1 | |||||||
MIRT727068 | NR2C2 | nuclear receptor subfamily 2 group C member 2 | ![]() |
1 | 1 | |||||||
MIRT727038 | OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 | ![]() |
1 | 1 | |||||||
MIRT727028 | TM9SF2 | transmembrane 9 superfamily member 2 | ![]() |
1 | 1 | |||||||
MIRT727021 | PANK1 | pantothenate kinase 1 | ![]() |
1 | 1 | |||||||
MIRT726974 | PEX12 | peroxisomal biogenesis factor 12 | ![]() |
1 | 1 | |||||||
MIRT726967 | PGD | phosphogluconate dehydrogenase | ![]() |
1 | 1 | |||||||
MIRT726910 | POLE4 | DNA polymerase epsilon 4, accessory subunit | ![]() |
1 | 1 | |||||||
MIRT726902 | POU2AF1 | POU class 2 associating factor 1 | ![]() |
1 | 1 | |||||||
MIRT726874 | PPP6C | protein phosphatase 6 catalytic subunit | ![]() |
1 | 1 | |||||||
MIRT726853 | PSMB5 | proteasome subunit beta 5 | ![]() |
1 | 1 | |||||||
MIRT726826 | RAB11FIP2 | RAB11 family interacting protein 2 | ![]() |
1 | 1 | |||||||
MIRT726812 | RAB40B | RAB40B, member RAS oncogene family | ![]() |
1 | 1 | |||||||
MIRT726789 | RAP2C | RAP2C, member of RAS oncogene family | ![]() |
1 | 1 | |||||||
MIRT726773 | RELT | RELT, TNF receptor | ![]() |
1 | 1 | |||||||
MIRT726764 | REXO1 | RNA exonuclease 1 homolog | ![]() |
1 | 1 | |||||||
MIRT726756 | RFWD2 | ring finger and WD repeat domain 2 | ![]() |
1 | 1 | |||||||
MIRT726720 | RNH1 | ribonuclease/angiogenin inhibitor 1 | ![]() |
1 | 1 | |||||||
MIRT726715 | RNMT | RNA guanine-7 methyltransferase | ![]() |
1 | 1 | |||||||
MIRT726712 | RNPS1 | RNA binding protein with serine rich domain 1 | ![]() |
1 | 1 | |||||||
MIRT726685 | RPL36 | ribosomal protein L36 | ![]() |
1 | 1 | |||||||
MIRT726680 | RPS5 | ribosomal protein S5 | ![]() |
1 | 1 | |||||||
MIRT726677 | RPS6KA3 | ribosomal protein S6 kinase A3 | ![]() |
1 | 1 | |||||||
MIRT726548 | SLC25A22 | solute carrier family 25 member 22 | ![]() |
1 | 1 | |||||||
MIRT726545 | SLC25A29 | solute carrier family 25 member 29 | ![]() |
1 | 1 | |||||||
MIRT726511 | SLC7A5 | solute carrier family 7 member 5 | ![]() |
1 | 1 | |||||||
MIRT726507 | SLC9A1 | solute carrier family 9 member A1 | ![]() |
1 | 1 | |||||||
MIRT726482 | SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | ![]() |
1 | 1 | |||||||
MIRT726462 | SPTLC1 | serine palmitoyltransferase long chain base subunit 1 | ![]() |
1 | 1 | |||||||
MIRT726455 | SRPK1 | SRSF protein kinase 1 | ![]() |
1 | 1 | |||||||
MIRT726422 | STX17 | syntaxin 17 | ![]() |
1 | 1 | |||||||
MIRT726410 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit | ![]() |
1 | 1 | |||||||
MIRT726384 | TASP1 | taspase 1 | ![]() |
1 | 1 | |||||||
MIRT726372 | TBC1D14 | TBC1 domain family member 14 | ![]() |
1 | 1 | |||||||
MIRT726367 | TBC1D20 | TBC1 domain family member 20 | ![]() |
1 | 1 | |||||||
MIRT726360 | TBCCD1 | TBCC domain containing 1 | ![]() |
1 | 1 | |||||||
MIRT726356 | TBL1XR1 | transducin beta like 1 X-linked receptor 1 | ![]() |
1 | 1 | |||||||
MIRT726348 | TCF3 | transcription factor 3 | ![]() |
1 | 1 | |||||||
MIRT726339 | TFB1M | transcription factor B1, mitochondrial | ![]() |
1 | 1 | |||||||
MIRT726325 | TIMM13 | translocase of inner mitochondrial membrane 13 | ![]() |
1 | 1 | |||||||
MIRT726322 | TKTL1 | transketolase like 1 | ![]() |
1 | 1 | |||||||
MIRT726317 | TLE4 | transducin like enhancer of split 4 | ![]() |
1 | 1 | |||||||
MIRT726307 | TMEM135 | transmembrane protein 135 | ![]() |
1 | 1 | |||||||
MIRT726287 | TMEM55B | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 | ![]() |
1 | 1 | |||||||
MIRT726280 | TMEM69 | transmembrane protein 69 | ![]() |
1 | 1 | |||||||
MIRT726238 | TRAM1 | translocation associated membrane protein 1 | ![]() |
1 | 1 | |||||||
MIRT726221 | TUBB | tubulin beta class I | ![]() |
1 | 1 | |||||||
MIRT726166 | USP31 | ubiquitin specific peptidase 31 | ![]() |
1 | 1 | |||||||
MIRT726158 | USP3 | ubiquitin specific peptidase 3 | ![]() |
1 | 1 | |||||||
MIRT726143 | VCL | vinculin | ![]() |
1 | 1 | |||||||
MIRT726132 | CHMP3 | charged multivesicular body protein 3 | ![]() |
1 | 1 | |||||||
MIRT726128 | VPS33B | VPS33B, late endosome and lysosome associated | ![]() |
1 | 1 | |||||||
MIRT726084 | ZBTB5 | zinc finger and BTB domain containing 5 | ![]() |
1 | 1 | |||||||
MIRT726007 | ZNF91 | zinc finger protein 91 | ![]() |
1 | 1 | |||||||
MIRT725130 | SYNRG | synergin gamma | ![]() |
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2 | 2 | ||||||
MIRT720153 | PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | ![]() |
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2 | 2 | ||||||
MIRT717465 | ADORA3 | adenosine A3 receptor | ![]() |
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2 | 2 | ||||||
MIRT716436 | RAB15 | RAB15, member RAS oncogene family | ![]() |
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2 | 2 | ||||||
MIRT714442 | ARHGAP32 | Rho GTPase activating protein 32 | ![]() |
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2 | 2 | ||||||
MIRT713423 | SLC35E2B | solute carrier family 35 member E2B | ![]() |
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2 | 2 | ||||||
MIRT702879 | HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | ![]() |
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2 | 2 | ||||||
MIRT702096 | MCFD2 | multiple coagulation factor deficiency 2 | ![]() |
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2 | 2 | ||||||
MIRT701510 | NEGR1 | neuronal growth regulator 1 | ![]() |
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2 | 2 | ||||||
MIRT693934 | HNRNPA1L2 | heterogeneous nuclear ribonucleoprotein A1-like 2 | ![]() |
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2 | 2 | ||||||
MIRT691713 | FLOT2 | flotillin 2 | ![]() |
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2 | 3 | ||||||
MIRT682518 | GLP2R | glucagon like peptide 2 receptor | ![]() |
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2 | 2 | ||||||
MIRT682280 | RS1 | retinoschisin 1 | ![]() |
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2 | 2 | ||||||
MIRT680986 | DCAF17 | DDB1 and CUL4 associated factor 17 | ![]() |
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2 | 2 | ||||||
MIRT659260 | CUL3 | cullin 3 | ![]() |
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5 | 2 | |||
MIRT658796 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | ![]() |
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2 | 2 | ||||||
MIRT655815 | NOTCH2 | notch 2 | ![]() |
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2 | 3 | ||||||
MIRT648788 | KLHL40 | kelch like family member 40 | ![]() |
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2 | 2 | ||||||
MIRT646599 | ANKRD36 | ankyrin repeat domain 36 | ![]() |
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2 | 2 | ||||||
MIRT645514 | BSPRY | B-box and SPRY domain containing | ![]() |
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2 | 2 | ||||||
MIRT640542 | C3orf36 | chromosome 3 open reading frame 36 | ![]() |
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2 | 2 | ||||||
MIRT621501 | GPRC5A | G protein-coupled receptor class C group 5 member A | ![]() |
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2 | 4 | ||||||
MIRT618900 | ANKMY1 | ankyrin repeat and MYND domain containing 1 | ![]() |
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2 | 2 | ||||||
MIRT616471 | ADRA2B | adrenoceptor alpha 2B | ![]() |
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2 | 2 | ||||||
MIRT614697 | TRAK1 | trafficking kinesin protein 1 | ![]() |
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2 | 2 | ||||||
MIRT576593 | Npepps | aminopeptidase puromycin sensitive | ![]() |
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2 | 2 | ||||||
MIRT576100 | Pdcd1 | programmed cell death 1 | ![]() |
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2 | 5 | ||||||
MIRT575928 | Dmpk | dystrophia myotonica-protein kinase | ![]() |
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2 | 7 | ||||||
MIRT575886 | Cask | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | ![]() |
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2 | 4 | ||||||
MIRT574595 | N4BP1 | NEDD4 binding protein 1 | ![]() |
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2 | 3 | ||||||
MIRT574542 | PDIA6 | protein disulfide isomerase family A member 6 | ![]() |
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2 | 4 | ||||||
MIRT574207 | CLEC2D | C-type lectin domain family 2 member D | ![]() |
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2 | 2 | ||||||
MIRT574062 | PROSC | pyridoxal phosphate binding protein | ![]() |
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2 | 2 | ||||||
MIRT571926 | LSM11 | LSM11, U7 small nuclear RNA associated | ![]() |
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2 | 3 | ||||||
MIRT571824 | PHF19 | PHD finger protein 19 | ![]() |
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5 | 2 | |||
MIRT571662 | SERBP1 | SERPINE1 mRNA binding protein 1 | ![]() |
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2 | 2 | ||||||
MIRT571431 | RIF1 | replication timing regulatory factor 1 | ![]() |
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2 | 2 | ||||||
MIRT571287 | TTLL5 | tubulin tyrosine ligase like 5 | ![]() |
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2 | 2 | ||||||
MIRT571123 | UBE2H | ubiquitin conjugating enzyme E2 H | ![]() |
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2 | 2 | ||||||
MIRT570464 | TLK1 | tousled like kinase 1 | ![]() |
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2 | 3 | ||||||
MIRT568621 | ACVR2A | activin A receptor type 2A | ![]() |
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2 | 2 | ||||||
MIRT568575 | AHNAK2 | AHNAK nucleoprotein 2 | ![]() |
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2 | 2 | ||||||
MIRT568477 | ARMC12 | armadillo repeat containing 12 | ![]() |
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2 | 2 | ||||||
MIRT568143 | CCDC88C | coiled-coil domain containing 88C | ![]() |
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2 | 2 | ||||||
MIRT568025 | CMTM4 | CKLF like MARVEL transmembrane domain containing 4 | ![]() |
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2 | 2 | ||||||
MIRT567482 | FZD9 | frizzled class receptor 9 | ![]() |
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2 | 2 | ||||||
MIRT567450 | GNG12 | G protein subunit gamma 12 | ![]() |
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2 | 2 | ||||||
MIRT567017 | KLHL15 | kelch like family member 15 | ![]() |
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2 | 2 | ||||||
MIRT566834 | MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | ![]() |
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2 | 2 | ||||||
MIRT566654 | NCKAP1 | NCK associated protein 1 | ![]() |
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2 | 2 | ||||||
MIRT566122 | RASEF | RAS and EF-hand domain containing | ![]() |
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2 | 2 | ||||||
MIRT565400 | TGFBR3 | transforming growth factor beta receptor 3 | ![]() |
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2 | 2 | ||||||
MIRT565041 | VAV2 | vav guanine nucleotide exchange factor 2 | ![]() |
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2 | 2 | ||||||
MIRT564987 | WNK3 | WNK lysine deficient protein kinase 3 | ![]() |
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2 | 2 | ||||||
MIRT564954 | XKR7 | XK related 7 | ![]() |
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2 | 2 | ||||||
MIRT564838 | ZBTB16 | zinc finger and BTB domain containing 16 | ![]() |
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2 | 2 | ||||||
MIRT564556 | CCDC80 | coiled-coil domain containing 80 | ![]() |
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2 | 2 | ||||||
MIRT564482 | ZNF391 | zinc finger protein 391 | ![]() |
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2 | 2 | ||||||
MIRT564336 | CCNT1 | cyclin T1 | ![]() |
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2 | 2 | ||||||
MIRT563900 | RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | ![]() |
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2 | 2 | ||||||
MIRT563849 | SMDT1 | single-pass membrane protein with aspartate rich tail 1 | ![]() |
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2 | 2 | ||||||
MIRT563705 | THRAP3 | thyroid hormone receptor associated protein 3 | ![]() |
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2 | 2 | ||||||
MIRT563507 | DLGAP3 | DLG associated protein 3 | ![]() |
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2 | 2 | ||||||
MIRT563090 | SLC25A12 | solute carrier family 25 member 12 | ![]() |
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2 | 3 | ||||||
MIRT562881 | KIAA1456 | KIAA1456 | ![]() |
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2 | 2 | ||||||
MIRT562204 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | ![]() |
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2 | 2 | ||||||
MIRT562031 | LANCL1 | LanC like 1 | ![]() |
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2 | 2 | ||||||
MIRT561878 | MSANTD4 | Myb/SANT DNA binding domain containing 4 with coiled-coils | ![]() |
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2 | 2 | ||||||
MIRT561404 | TUBB2A | tubulin beta 2A class IIa | ![]() |
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2 | 2 | ||||||
MIRT561153 | KRT33B | keratin 33B | ![]() |
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2 | 2 | ||||||
MIRT560855 | OSBPL3 | oxysterol binding protein like 3 | ![]() |
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2 | 2 | ||||||
MIRT559536 | ARHGAP12 | Rho GTPase activating protein 12 | ![]() |
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2 | 5 | ||||||
MIRT559155 | BTN3A3 | butyrophilin subfamily 3 member A3 | ![]() |
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2 | 2 | ||||||
MIRT559006 | CA8 | carbonic anhydrase 8 | ![]() |
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2 | 2 | ||||||
MIRT558664 | CNKSR3 | CNKSR family member 3 | ![]() |
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2 | 2 | ||||||
MIRT558511 | CYP26B1 | cytochrome P450 family 26 subfamily B member 1 | ![]() |
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2 | 4 | ||||||
MIRT558041 | EXT1 | exostosin glycosyltransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT557484 | GPR27 | G protein-coupled receptor 27 | ![]() |
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2 | 4 | ||||||
MIRT557284 | HIST2H2BE | histone cluster 2 H2B family member e | ![]() |
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2 | 2 | ||||||
MIRT556861 | KANK1 | KN motif and ankyrin repeat domains 1 | ![]() |
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2 | 4 | ||||||
MIRT556385 | LURAP1L | leucine rich adaptor protein 1 like | ![]() |
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2 | 2 | ||||||
MIRT555431 | PPAP2B | phospholipid phosphatase 3 | ![]() |
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2 | 2 | ||||||
MIRT555278 | PRDM4 | PR/SET domain 4 | ![]() |
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2 | 2 | ||||||
MIRT555229 | PRKAA1 | protein kinase AMP-activated catalytic subunit alpha 1 | ![]() |
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2 | 4 | ||||||
MIRT555143 | PTPRD | protein tyrosine phosphatase, receptor type D | ![]() |
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2 | 2 | ||||||
MIRT555035 | RAB23 | RAB23, member RAS oncogene family | ![]() |
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2 | 2 | ||||||
MIRT554965 | RACGAP1 | Rac GTPase activating protein 1 | ![]() |
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2 | 2 | ||||||
MIRT554702 | RNF149 | ring finger protein 149 | ![]() |
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2 | 2 | ||||||
MIRT553812 | SZRD1 | SUZ RNA binding domain containing 1 | ![]() |
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2 | 4 | ||||||
MIRT553777 | TAF13 | TATA-box binding protein associated factor 13 | ![]() |
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2 | 4 | ||||||
MIRT553620 | TM7SF3 | transmembrane 7 superfamily member 3 | ![]() |
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2 | 2 | ||||||
MIRT553565 | TMEM161B | transmembrane protein 161B | ![]() |
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2 | 2 | ||||||
MIRT553442 | TPM3 | tropomyosin 3 | ![]() |
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2 | 2 | ||||||
MIRT552744 | YRDC | yrdC N6-threonylcarbamoyltransferase domain containing | ![]() |
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2 | 2 | ||||||
MIRT552348 | ZNF704 | zinc finger protein 704 | ![]() |
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2 | 2 | ||||||
MIRT552039 | DNAJC10 | DnaJ heat shock protein family (Hsp40) member C10 | ![]() |
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2 | 2 | ||||||
MIRT551740 | SSU72 | SSU72 homolog, RNA polymerase II CTD phosphatase | ![]() |
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2 | 2 | ||||||
MIRT551621 | ZNF267 | zinc finger protein 267 | ![]() |
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2 | 2 | ||||||
MIRT551383 | EPM2AIP1 | EPM2A interacting protein 1 | ![]() |
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2 | 2 | ||||||
MIRT550827 | FAM229B | family with sequence similarity 229 member B | ![]() |
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2 | 2 | ||||||
MIRT550619 | MTHFR | methylenetetrahydrofolate reductase | ![]() |
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2 | 2 | ||||||
MIRT550470 | OSCAR | osteoclast associated, immunoglobulin-like receptor | ![]() |
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2 | 4 | ||||||
MIRT550405 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) | ![]() |
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2 | 4 | ||||||
MIRT549389 | AMOT | angiomotin | ![]() |
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2 | 2 | ||||||
MIRT549278 | ASH1L | ASH1 like histone lysine methyltransferase | ![]() |
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2 | 3 | ||||||
MIRT549123 | C11orf24 | chromosome 11 open reading frame 24 | ![]() |
![]() |
2 | 4 | ||||||
MIRT549076 | CACUL1 | CDK2 associated cullin domain 1 | ![]() |
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2 | 2 | ||||||
MIRT548946 | CDK17 | cyclin dependent kinase 17 | ![]() |
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2 | 3 | ||||||
MIRT548809 | CLIP4 | CAP-Gly domain containing linker protein family member 4 | ![]() |
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2 | 4 | ||||||
MIRT548727 | CRK | CRK proto-oncogene, adaptor protein | ![]() |
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2 | 2 | ||||||
MIRT548275 | FBXL20 | F-box and leucine rich repeat protein 20 | ![]() |
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2 | 2 | ||||||
MIRT548219 | FKBP1A | FK506 binding protein 1A | ![]() |
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2 | 2 | ||||||
MIRT548018 | GRB2 | growth factor receptor bound protein 2 | ![]() |
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2 | 4 | ||||||
MIRT548001 | HCFC2 | host cell factor C2 | ![]() |
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2 | 4 | ||||||
MIRT547968 | HIGD1A | HIG1 hypoxia inducible domain family member 1A | ![]() |
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2 | 4 | ||||||
MIRT547702 | KPNA1 | karyopherin subunit alpha 1 | ![]() |
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2 | 4 | ||||||
MIRT547661 | KPNA3 | karyopherin subunit alpha 3 | ![]() |
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2 | 2 | ||||||
MIRT547546 | LRRFIP2 | LRR binding FLII interacting protein 2 | ![]() |
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2 | 4 | ||||||
MIRT547463 | MBD4 | methyl-CpG binding domain 4, DNA glycosylase | ![]() |
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2 | 2 | ||||||
MIRT547406 | MKX | mohawk homeobox | ![]() |
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2 | 2 | ||||||
MIRT547305 | NUCKS1 | nuclear casein kinase and cyclin dependent kinase substrate 1 | ![]() |
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2 | 3 | ||||||
MIRT547233 | PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | ![]() |
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2 | 4 | ||||||
MIRT547131 | PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | ![]() |
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2 | 2 | ||||||
MIRT547069 | PNISR | PNN interacting serine and arginine rich protein | ![]() |
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2 | 3 | ||||||
MIRT546640 | RTN4 | reticulon 4 | ![]() |
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2 | 2 | ||||||
MIRT546619 | RUNX1T1 | RUNX1 translocation partner 1 | ![]() |
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2 | 2 | ||||||
MIRT546611 | SALL1 | spalt like transcription factor 1 | ![]() |
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2 | 4 | ||||||
MIRT546118 | USP48 | ubiquitin specific peptidase 48 | ![]() |
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2 | 4 | ||||||
MIRT545973 | YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta | ![]() |
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2 | 2 | ||||||
MIRT545961 | ZBTB10 | zinc finger and BTB domain containing 10 | ![]() |
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2 | 2 | ||||||
MIRT545686 | DECR1 | 2,4-dienoyl-CoA reductase 1 | ![]() |
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2 | 2 | ||||||
MIRT545351 | CCDC83 | coiled-coil domain containing 83 | ![]() |
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2 | 2 | ||||||
MIRT545190 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | ![]() |
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2 | 4 | ||||||
MIRT544969 | UGT2B4 | UDP glucuronosyltransferase family 2 member B4 | ![]() |
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2 | 2 | ||||||
MIRT544916 | CLSPN | claspin | ![]() |
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2 | 2 | ||||||
MIRT544593 | AP5Z1 | adaptor related protein complex 5 zeta 1 subunit | ![]() |
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2 | 4 | ||||||
MIRT544575 | POLDIP3 | DNA polymerase delta interacting protein 3 | ![]() |
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2 | 2 | ||||||
MIRT543839 | GSG1 | germ cell associated 1 | ![]() |
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2 | 2 | ||||||
MIRT543801 | RALGAPB | Ral GTPase activating protein non-catalytic beta subunit | ![]() |
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2 | 4 | ||||||
MIRT543529 | PRSS21 | protease, serine 21 | ![]() |
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2 | 2 | ||||||
MIRT543411 | ANAPC13 | anaphase promoting complex subunit 13 | ![]() |
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2 | 2 | ||||||
MIRT543310 | ZNF585B | zinc finger protein 585B | ![]() |
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2 | 2 | ||||||
MIRT543062 | BAZ2A | bromodomain adjacent to zinc finger domain 2A | ![]() |
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2 | 2 | ||||||
MIRT542837 | PDCD1 | programmed cell death 1 | ![]() |
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2 | 7 | ||||||
MIRT542810 | PHC3 | polyhomeotic homolog 3 | ![]() |
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2 | 3 | ||||||
MIRT541432 | CBX4 | chromobox 4 | ![]() |
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2 | 3 | ||||||
MIRT541217 | HOXA10 | homeobox A10 | ![]() |
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2 | 2 | ||||||
MIRT540847 | GNAT1 | G protein subunit alpha transducin 1 | ![]() |
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2 | 4 | ||||||
MIRT539902 | RPL14 | ribosomal protein L14 | ![]() |
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2 | 4 | ||||||
MIRT537815 | EFNB2 | ephrin B2 | ![]() |
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2 | 4 | ||||||
MIRT522778 | LAMP2 | lysosomal associated membrane protein 2 | ![]() |
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2 | 6 | ||||||
MIRT522098 | NUFIP2 | NUFIP2, FMR1 interacting protein 2 | ![]() |
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2 | 5 | ||||||
MIRT521818 | POM121C | POM121 transmembrane nucleoporin C | ![]() |
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2 | 2 | ||||||
MIRT521207 | SBNO1 | strawberry notch homolog 1 | ![]() |
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2 | 6 | ||||||
MIRT521055 | SLC2A3 | solute carrier family 2 member 3 | ![]() |
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2 | 4 | ||||||
MIRT518998 | NNT | nicotinamide nucleotide transhydrogenase | ![]() |
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2 | 4 | ||||||
MIRT518533 | FLCN | folliculin | ![]() |
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2 | 6 | ||||||
MIRT518095 | TRIM35 | tripartite motif containing 35 | ![]() |
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2 | 2 | ||||||
MIRT514042 | ATG14 | autophagy related 14 | ![]() |
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2 | 2 | ||||||
MIRT514020 | CAMSAP1 | calmodulin regulated spectrin associated protein 1 | ![]() |
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2 | 5 | ||||||
MIRT513854 | JARID2 | jumonji and AT-rich interaction domain containing 2 | ![]() |
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2 | 8 | ||||||
MIRT512646 | CPEB3 | cytoplasmic polyadenylation element binding protein 3 | ![]() |
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2 | 5 | ||||||
MIRT512288 | ARHGDIA | Rho GDP dissociation inhibitor alpha | ![]() |
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2 | 7 | ||||||
MIRT511847 | GPATCH8 | G-patch domain containing 8 | ![]() |
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2 | 5 | ||||||
MIRT510047 | AKR1B10 | aldo-keto reductase family 1 member B10 | ![]() |
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2 | 4 | ||||||
MIRT509693 | ATAD5 | ATPase family, AAA domain containing 5 | ![]() |
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2 | 4 | ||||||
MIRT509368 | DMPK | DM1 protein kinase | ![]() |
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2 | 11 | ||||||
MIRT508644 | CASK | calcium/calmodulin dependent serine protein kinase | ![]() |
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2 | 5 | ||||||
MIRT508041 | AXIN2 | axin 2 | ![]() |
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2 | 6 | ||||||
MIRT507877 | CBX6 | chromobox 6 | ![]() |
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2 | 2 | ||||||
MIRT507853 | CCNE2 | cyclin E2 | ![]() |
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2 | 6 | ||||||
MIRT507820 | CDK1 | cyclin dependent kinase 1 | ![]() |
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2 | 6 | ||||||
MIRT507002 | HNRNPDL | heterogeneous nuclear ribonucleoprotein D like | ![]() |
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2 | 6 | ||||||
MIRT506854 | KIF23 | kinesin family member 23 | ![]() |
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2 | 7 | ||||||
MIRT506487 | MYO5A | myosin VA | ![]() |
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2 | 7 | ||||||
MIRT506194 | PHKA1 | phosphorylase kinase regulatory subunit alpha 1 | ![]() |
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2 | 6 | ||||||
MIRT506166 | PLAG1 | PLAG1 zinc finger | ![]() |
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2 | 9 | ||||||
MIRT506138 | PLRG1 | pleiotropic regulator 1 | ![]() |
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2 | 4 | ||||||
MIRT506112 | PPIG | peptidylprolyl isomerase G | ![]() |
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2 | 6 | ||||||
MIRT505930 | RCAN3 | RCAN family member 3 | ![]() |
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2 | 4 | ||||||
MIRT505911 | RIMS3 | regulating synaptic membrane exocytosis 3 | ![]() |
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2 | 6 | ||||||
MIRT505686 | SESTD1 | SEC14 and spectrin domain containing 1 | ![]() |
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2 | 6 | ||||||
MIRT505549 | SNX16 | sorting nexin 16 | ![]() |
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2 | 6 | ||||||
MIRT505505 | SRSF1 | serine and arginine rich splicing factor 1 | ![]() |
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2 | 6 | ||||||
MIRT505398 | TMEM100 | transmembrane protein 100 | ![]() |
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2 | 2 | ||||||
MIRT505349 | TMEM245 | transmembrane protein 245 | ![]() |
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2 | 6 | ||||||
MIRT505116 | YTHDC1 | YTH domain containing 1 | ![]() |
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2 | 6 | ||||||
MIRT504855 | HAUS3 | HAUS augmin like complex subunit 3 | ![]() |
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2 | 6 | ||||||
MIRT504540 | ZNF620 | zinc finger protein 620 | ![]() |
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2 | 6 | ||||||
MIRT504338 | ASGR2 | asialoglycoprotein receptor 2 | ![]() |
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2 | 6 | ||||||
MIRT503140 | ATG9A | autophagy related 9A | ![]() |
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2 | 7 | ||||||
MIRT502950 | CDC37L1 | cell division cycle 37 like 1 | ![]() |
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2 | 9 | ||||||
MIRT502922 | CDCA4 | cell division cycle associated 4 | ![]() |
![]() |
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4 | 9 | ||||
MIRT502643 | DDX3X | DEAD-box helicase 3, X-linked | ![]() |
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2 | 8 | ||||||
MIRT502570 | E2F7 | E2F transcription factor 7 | ![]() |
![]() |
2 | 11 | ||||||
MIRT502496 | FAM122B | family with sequence similarity 122B | ![]() |
![]() |
2 | 8 | ||||||
MIRT502151 | KIF5B | kinesin family member 5B | ![]() |
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2 | 9 | ||||||
MIRT502038 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 | ![]() |
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2 | 2 | ||||||
MIRT501506 | PRICKLE2 | prickle planar cell polarity protein 2 | ![]() |
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2 | 2 | ||||||
MIRT501089 | SMAD7 | SMAD family member 7 | ![]() |
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2 | 8 | ||||||
MIRT500953 | SREK1 | splicing regulatory glutamic acid and lysine rich protein 1 | ![]() |
![]() |
2 | 8 | ||||||
MIRT500936 | SRPR | SRP receptor alpha subunit | ![]() |
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2 | 7 | ||||||
MIRT500860 | SYPL1 | synaptophysin like 1 | ![]() |
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2 | 8 | ||||||
MIRT500580 | USP53 | ubiquitin specific peptidase 53 | ![]() |
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2 | 2 | ||||||
MIRT500425 | ZMAT3 | zinc finger matrin-type 3 | ![]() |
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2 | 4 | ||||||
MIRT500321 | ZNF622 | zinc finger protein 622 | ![]() |
![]() |
2 | 9 | ||||||
MIRT500097 | L2HGDH | L-2-hydroxyglutarate dehydrogenase | ![]() |
![]() |
2 | 8 | ||||||
MIRT499619 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 | ![]() |
![]() |
2 | 8 | ||||||
MIRT499456 | ODF2L | outer dense fiber of sperm tails 2 like | ![]() |
![]() |
2 | 8 | ||||||
MIRT498984 | ORC4 | origin recognition complex subunit 4 | ![]() |
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2 | 8 | ||||||
MIRT497776 | KIAA0895 | KIAA0895 | ![]() |
![]() |
2 | 2 | ||||||
MIRT496019 | CD180 | CD180 molecule | ![]() |
![]() |
2 | 2 | ||||||
MIRT495146 | ZNRF1 | zinc and ring finger 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT494354 | CASKIN1 | CASK interacting protein 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT492715 | PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein | ![]() |
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2 | 2 | ||||||
MIRT487394 | C10orf54 | V-set immunoregulatory receptor | ![]() |
![]() |
2 | 2 | ||||||
MIRT485215 | PRKAR2A | protein kinase cAMP-dependent type II regulatory subunit alpha | ![]() |
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2 | 8 | ||||||
MIRT484778 | ABCC6 | ATP binding cassette subfamily C member 6 | ![]() |
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2 | 4 | ||||||
MIRT482581 | ABHD2 | abhydrolase domain containing 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT482556 | ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | ![]() |
![]() |
2 | 10 | ||||||
MIRT482370 | AGO2 | argonaute 2, RISC catalytic component | ![]() |
![]() |
2 | 2 | ||||||
MIRT481181 | AVL9 | AVL9 cell migration associated | ![]() |
![]() |
2 | 6 | ||||||
MIRT479988 | CARD10 | caspase recruitment domain family member 10 | ![]() |
![]() |
2 | 2 | ||||||
MIRT479457 | CDK6 | cyclin dependent kinase 6 | ![]() |
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2 | 2 | ||||||
MIRT478911 | CPSF7 | cleavage and polyadenylation specific factor 7 | ![]() |
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2 | 6 | ||||||
MIRT477849 | DYRK3 | dual specificity tyrosine phosphorylation regulated kinase 3 | ![]() |
![]() |
2 | 2 | ||||||
MIRT477565 | EIF1AX | eukaryotic translation initiation factor 1A, X-linked | ![]() |
![]() |
2 | 8 | ||||||
MIRT476698 | FURIN | furin, paired basic amino acid cleaving enzyme | ![]() |
![]() |
2 | 2 | ||||||
MIRT476276 | GNAL | G protein subunit alpha L | ![]() |
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2 | 6 | ||||||
MIRT476259 | GNB1 | G protein subunit beta 1 | ![]() |
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2 | 7 | ||||||
MIRT475843 | HDGF | heparin binding growth factor | ![]() |
![]() |
2 | 4 | ||||||
MIRT475720 | HEYL | hes related family bHLH transcription factor with YRPW motif-like | ![]() |
![]() |
2 | 2 | ||||||
MIRT475539 | HOXA3 | homeobox A3 | ![]() |
![]() |
2 | 8 | ||||||
MIRT475123 | IPPK | inositol-pentakisphosphate 2-kinase | ![]() |
![]() |
2 | 2 | ||||||
MIRT475068 | IVNS1ABP | influenza virus NS1A binding protein | ![]() |
![]() |
2 | 6 | ||||||
MIRT474828 | KIAA0226 | RUN and cysteine rich domain containing beclin 1 interacting protein | ![]() |
![]() |
2 | 2 | ||||||
MIRT474318 | LAMC1 | laminin subunit gamma 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT472665 | NAA25 | N(alpha)-acetyltransferase 25, NatB auxiliary subunit | ![]() |
![]() |
2 | 4 | ||||||
MIRT472263 | NFIC | nuclear factor I C | ![]() |
![]() |
2 | 2 | ||||||
MIRT471956 | NR6A1 | nuclear receptor subfamily 6 group A member 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT471495 | PDE4D | phosphodiesterase 4D | ![]() |
![]() |
2 | 4 | ||||||
MIRT471038 | PISD | phosphatidylserine decarboxylase | ![]() |
![]() |
2 | 10 | ||||||
MIRT469415 | REL | REL proto-oncogene, NF-kB subunit | ![]() |
![]() |
2 | 6 | ||||||
MIRT469090 | RNF168 | ring finger protein 168 | ![]() |
![]() |
2 | 2 | ||||||
MIRT468676 | SEC24A | SEC24 homolog A, COPII coat complex component | ![]() |
![]() |
2 | 4 | ||||||
MIRT468151 | SH3BP4 | SH3 domain binding protein 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT468052 | SIK1 | salt inducible kinase 1 | ![]() |
![]() |
2 | 3 | ||||||
MIRT467002 | SSRP1 | structure specific recognition protein 1 | ![]() |
![]() |
2 | 5 | ||||||
MIRT466917 | STK38 | serine/threonine kinase 38 | ![]() |
![]() |
2 | 10 | ||||||
MIRT466436 | TFAP2A | transcription factor AP-2 alpha | ![]() |
![]() |
2 | 8 | ||||||
MIRT466298 | TM4SF1 | transmembrane 4 L six family member 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT466008 | TMEM189 | transmembrane protein 189 | ![]() |
![]() |
2 | 8 | ||||||
MIRT465926 | TMEM189-UBE2V1 | TMEM189-UBE2V1 readthrough | ![]() |
![]() |
2 | 8 | ||||||
MIRT465570 | TOB2 | transducer of ERBB2, 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT465165 | TSC22D2 | TSC22 domain family member 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT464751 | UBE2Q1 | ubiquitin conjugating enzyme E2 Q1 | ![]() |
![]() |
2 | 3 | ||||||
MIRT464668 | UBE2V1 | ubiquitin conjugating enzyme E2 V1 | ![]() |
![]() |
2 | 8 | ||||||
MIRT463167 | ZNF367 | zinc finger protein 367 | ![]() |
![]() |
2 | 10 | ||||||
MIRT461564 | ACTR3B | ARP3 actin related protein 3 homolog B | ![]() |
![]() |
2 | 2 | ||||||
MIRT460438 | DOCK11 | dedicator of cytokinesis 11 | ![]() |
![]() |
2 | 2 | ||||||
MIRT460224 | FGFR4 | fibroblast growth factor receptor 4 | ![]() |
![]() |
2 | 2 | ||||||
MIRT456867 | ZNF460 | zinc finger protein 460 | ![]() |
![]() |
2 | 10 | ||||||
MIRT454970 | TPM2 | tropomyosin 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT453754 | CSNK1E | casein kinase 1 epsilon | ![]() |
![]() |
2 | 2 | ||||||
MIRT453288 | EFTUD2 | elongation factor Tu GTP binding domain containing 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT451839 | ALDH3B1 | aldehyde dehydrogenase 3 family member B1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT449190 | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor | ![]() |
![]() |
2 | 2 | ||||||
MIRT448440 | TLL1 | tolloid like 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT447778 | DMRT2 | doublesex and mab-3 related transcription factor 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT446508 | ASCC1 | activating signal cointegrator 1 complex subunit 1 | ![]() |
![]() |
2 | 2 | ||||||
MIRT443809 | SIDT2 | SID1 transmembrane family member 2 | ![]() |
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2 | 2 | ||||||
MIRT438610 | RET | ret proto-oncogene | ![]() |
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3 | 1 | |||||
MIRT438163 | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | ![]() |
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3 | 1 | |||||
MIRT437998 | KLF6 | Kruppel like factor 6 | ![]() |
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2 | 1 | ||||||
MIRT327962 | CHIC1 | cysteine rich hydrophobic domain 1 | ![]() |
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2 | 6 | ||||||
MIRT326301 | OCRL | OCRL, inositol polyphosphate-5-phosphatase | ![]() |
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2 | 2 | ||||||
MIRT324839 | IFT74 | intraflagellar transport 74 | ![]() |
1 | 1 | |||||||
MIRT320626 | ZNRF2 | zinc and ring finger 2 | ![]() |
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2 | 2 | ||||||
MIRT319331 | CAPZA2 | capping actin protein of muscle Z-line alpha subunit 2 | ![]() |
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2 | 2 | ||||||
MIRT317722 | PPIL1 | peptidylprolyl isomerase like 1 | ![]() |
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2 | 7 | ||||||
MIRT314051 | PIK3R1 | phosphoinositide-3-kinase regulatory subunit 1 | ![]() |
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2 | 8 | ||||||
MIRT313675 | ITGA2 | integrin subunit alpha 2 | ![]() |
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2 | 2 | ||||||
MIRT307141 | CTDSPL | CTD small phosphatase like | ![]() |
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2 | 4 | ||||||
MIRT302825 | SOCS5 | suppressor of cytokine signaling 5 | ![]() |
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2 | 2 | ||||||
MIRT302611 | CRIM1 | cysteine rich transmembrane BMP regulator 1 | ![]() |
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2 | 6 | ||||||
MIRT300992 | MTMR3 | myotubularin related protein 3 | ![]() |
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2 | 2 | ||||||
MIRT300100 | STRADB | STE20-related kinase adaptor beta | ![]() |
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2 | 2 | ||||||
MIRT297778 | GABPA | GA binding protein transcription factor alpha subunit | ![]() |
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2 | 4 | ||||||
MIRT295810 | CHMP4B | charged multivesicular body protein 4B | ![]() |
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2 | 2 | ||||||
MIRT294283 | ZFP28 | ZFP28 zinc finger protein | ![]() |
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2 | 2 | ||||||
MIRT289625 | CBX2 | chromobox 2 | ![]() |
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2 | 2 | ||||||
MIRT286968 | MLLT6 | MLLT6, PHD finger containing | ![]() |
1 | 1 | |||||||
MIRT282532 | SLCO3A1 | solute carrier organic anion transporter family member 3A1 | ![]() |
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2 | 2 | ||||||
MIRT277504 | PPP2R5C | protein phosphatase 2 regulatory subunit B'gamma | ![]() |
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2 | 4 | ||||||
MIRT274741 | RAB3IP | RAB3A interacting protein | ![]() |
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2 | 2 | ||||||
MIRT273665 | HOXC8 | homeobox C8 | ![]() |
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2 | 2 | ||||||
MIRT270552 | SETD1B | SET domain containing 1B | ![]() |
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2 | 2 | ||||||
MIRT270454 | SIRT4 | sirtuin 4 | ![]() |
1 | 1 | |||||||
MIRT267527 | C1ORF226 | chromosome 1 open reading frame 226 | ![]() |
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2 | 2 | ||||||
MIRT267254 | TMEM109 | transmembrane protein 109 | ![]() |
1 | 1 | |||||||
MIRT265076 | CHEK1 | checkpoint kinase 1 | ![]() |
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2 | 3 | ||||||
MIRT265056 | TBRG1 | transforming growth factor beta regulator 1 | ![]() |
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2 | 2 | ||||||
MIRT258410 | WIPI2 | WD repeat domain, phosphoinositide interacting 2 | ![]() |
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2 | 3 | ||||||
MIRT256305 | CDC42SE2 | CDC42 small effector 2 | ![]() |
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2 | 2 | ||||||
MIRT255333 | SRPRB | SRP receptor beta subunit | ![]() |
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2 | 5 | ||||||
MIRT251487 | DYNLL2 | dynein light chain LC8-type 2 | ![]() |
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2 | 4 | ||||||
MIRT249449 | ZNF691 | zinc finger protein 691 | ![]() |
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2 | 4 | ||||||
MIRT248765 | ATXN7L3B | ataxin 7 like 3B | ![]() |
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2 | 4 | ||||||
MIRT248550 | PDIK1L | PDLIM1 interacting kinase 1 like | ![]() |
1 | 1 | |||||||
MIRT247368 | GABARAPL1 | GABA type A receptor associated protein like 1 | ![]() |
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2 | 6 | ||||||
MIRT247236 | ELK4 | ELK4, ETS transcription factor | ![]() |
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2 | 4 | ||||||
MIRT247095 | WEE1 | WEE1 G2 checkpoint kinase | ![]() |
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2 | 4 | ||||||
MIRT246938 | PRRC2C | proline rich coiled-coil 2C | ![]() |
1 | 1 | |||||||
MIRT245003 | ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | ![]() |
1 | 1 | |||||||
MIRT234342 | MSL1 | male specific lethal 1 homolog | ![]() |
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2 | 8 | ||||||
MIRT230120 | DDX3Y | DEAD-box helicase 3, Y-linked | ![]() |
1 | 1 | |||||||
MIRT229860 | YIPF6 | Yip1 domain family member 6 | ![]() |
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2 | 2 | ||||||
MIRT229343 | ZNF449 | zinc finger protein 449 | ![]() |
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2 | 2 | ||||||
MIRT224965 | BAG4 | BCL2 associated athanogene 4 | ![]() |
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2 | 2 | ||||||
MIRT223681 | FZD6 | frizzled class receptor 6 | ![]() |
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2 | 6 | ||||||
MIRT217743 | TBPL1 | TATA-box binding protein like 1 | ![]() |
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2 | 3 | ||||||
MIRT212604 | RBPJ | recombination signal binding protein for immunoglobulin kappa J region | ![]() |
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2 | 8 | ||||||
MIRT211314 | HSPA4L | heat shock protein family A (Hsp70) member 4 like | ![]() |
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2 | 4 | ||||||
MIRT211199 | FGF2 | fibroblast growth factor 2 | ![]() |
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2 | 4 | ||||||
MIRT206020 | NUP50 | nucleoporin 50 | ![]() |
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2 | 7 | ||||||
MIRT204741 | BZW1 | basic leucine zipper and W2 domains 1 | ![]() |
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2 | 12 | ||||||
MIRT204623 | MOB4 | MOB family member 4, phocein | ![]() |
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2 | 8 | ||||||
MIRT204592 | HSPE1-MOB4 | HSPE1-MOB4 readthrough | ![]() |
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2 | 8 | ||||||
MIRT201456 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | ![]() |
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2 | 8 | ||||||
MIRT196450 | TAOK1 | TAO kinase 1 | ![]() |
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2 | 2 | ||||||
MIRT196275 | PAFAH1B1 | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | ![]() |
1 | 1 | |||||||
MIRT194903 | RBBP6 | RB binding protein 6, ubiquitin ligase | ![]() |
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2 | 8 | ||||||
MIRT194237 | FAM103A1 | family with sequence similarity 103 member A1 | ![]() |
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2 | 6 | ||||||
MIRT191625 | SLC39A9 | solute carrier family 39 member 9 | ![]() |
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2 | 6 | ||||||
MIRT191454 | PPM1A | protein phosphatase, Mg2+/Mn2+ dependent 1A | ![]() |
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2 | 2 | ||||||
MIRT190184 | GPR180 | G protein-coupled receptor 180 | ![]() |
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2 | 6 | ||||||
MIRT189961 | AGO4 | argonaute 4, RISC catalytic component | ![]() |
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2 | 2 | ||||||
MIRT189760 | CDADC1 | cytidine and dCMP deaminase domain containing 1 | ![]() |
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2 | 2 | ||||||
MIRT186371 | PNRC2 | proline rich nuclear receptor coactivator 2 | ![]() |
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2 | 2 | ||||||
MIRT180909 | RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | ![]() |
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2 | 8 | ||||||
MIRT179008 | PAFAH1B2 | platelet activating factor acetylhydrolase 1b catalytic subunit 2 | ![]() |
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2 | 2 | ||||||
MIRT175524 | ZBTB33 | zinc finger and BTB domain containing 33 | ![]() |
1 | 1 | |||||||
MIRT175232 | PSAT1 | phosphoserine aminotransferase 1 | ![]() |
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2 | 7 | ||||||
MIRT174781 | RNF38 | ring finger protein 38 | ![]() |
1 | 1 | |||||||
MIRT172813 | HMBOX1 | homeobox containing 1 | ![]() |
1 | 1 | |||||||
MIRT171597 | SUN1 | Sad1 and UNC84 domain containing 1 | ![]() |
1 | 1 | |||||||
MIRT170733 | UBE3C | ubiquitin protein ligase E3C | ![]() |
1 | 1 | |||||||
MIRT170136 | KLHDC10 | kelch domain containing 10 | ![]() |
1 | 1 | |||||||
MIRT169058 | IRF4 | interferon regulatory factor 4 | ![]() |
1 | 1 | |||||||
MIRT168680 | CDKN1A | cyclin dependent kinase inhibitor 1A | ![]() |
1 | 1 | |||||||
MIRT165883 | CREBRF | CREB3 regulatory factor | ![]() |
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2 | 3 | ||||||
MIRT165172 | GRAMD3 | GRAM domain containing 2B | ![]() |
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2 | 3 | ||||||
MIRT164952 | TADA2B | transcriptional adaptor 2B | ![]() |
1 | 1 | |||||||
MIRT164260 | CPEB2 | cytoplasmic polyadenylation element binding protein 2 | ![]() |
1 | 1 | |||||||
MIRT163253 | PRKCD | protein kinase C delta | ![]() |
1 | 1 | |||||||
MIRT160169 | TET3 | tet methylcytosine dioxygenase 3 | ![]() |
1 | 1 | |||||||
MIRT159580 | PEX13 | peroxisomal biogenesis factor 13 | ![]() |
1 | 1 | |||||||
MIRT158990 | EPT1 | selenoprotein I | ![]() |
1 | 1 | |||||||
MIRT158519 | TNRC6B | trinucleotide repeat containing 6B | ![]() |
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2 | 5 | ||||||
MIRT156452 | ATP5G3 | ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) | ![]() |
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2 | 2 | ||||||
MIRT154392 | CDS2 | CDP-diacylglycerol synthase 2 | ![]() |
1 | 1 | |||||||
MIRT154043 | RASSF2 | Ras association domain family member 2 | ![]() |
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2 | 2 | ||||||
MIRT152922 | NOL4L | nucleolar protein 4 like | ![]() |
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2 | 3 | ||||||
MIRT152736 | KIF3B | kinesin family member 3B | ![]() |
1 | 1 | |||||||
MIRT152503 | ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | ![]() |
1 | 1 | |||||||
MIRT152274 | TNFSF9 | TNF superfamily member 9 | ![]() |
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2 | 3 | ||||||
MIRT150354 | IER2 | immediate early response 2 | ![]() |
1 | 1 | |||||||
MIRT148302 | RNF138 | ring finger protein 138 | ![]() |
1 | 1 | |||||||
MIRT146496 | SNX11 | sorting nexin 11 | ![]() |
1 | 1 | |||||||
MIRT146351 | PNPO | pyridoxamine 5'-phosphate oxidase | ![]() |
1 | 1 | |||||||
MIRT146014 | EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit | ![]() |
1 | 1 | |||||||
MIRT145377 | ANKRD13B | ankyrin repeat domain 13B | ![]() |
1 | 1 | |||||||
MIRT144019 | PSKH1 | protein serine kinase H1 | ![]() |
1 | 1 | |||||||
MIRT142237 | DCTN5 | dynactin subunit 5 | ![]() |
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2 | 9 | ||||||
MIRT141279 | UBE2Q2 | ubiquitin conjugating enzyme E2 Q2 | ![]() |
1 | 1 | |||||||
MIRT141243 | SCAMP5 | secretory carrier membrane protein 5 | ![]() |
1 | 1 | |||||||
MIRT140820 | SMAD3 | SMAD family member 3 | ![]() |
1 | 1 | |||||||
MIRT140146 | SPRED1 | sprouty related EVH1 domain containing 1 | ![]() |
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2 | 3 | ||||||
MIRT137517 | RCOR1 | REST corepressor 1 | ![]() |
1 | 1 | |||||||
MIRT133769 | SKI | SKI proto-oncogene | ![]() |
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2 | 3 | ||||||
MIRT133334 | BCL7A | BCL tumor suppressor 7A | ![]() |
1 | 1 | |||||||
MIRT132831 | MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | ![]() |
1 | 1 | |||||||
MIRT132734 | RASSF5 | Ras association domain family member 5 | ![]() |
1 | 1 | |||||||
MIRT131097 | TMEM138 | transmembrane protein 138 | ![]() |
1 | 1 | |||||||
MIRT130380 | PTPRJ | protein tyrosine phosphatase, receptor type J | ![]() |
1 | 1 | |||||||
MIRT129055 | ARCN1 | archain 1 | ![]() |
1 | 1 | |||||||
MIRT128798 | UBE4A | ubiquitination factor E4A | ![]() |
1 | 1 | |||||||
MIRT127725 | ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | ![]() |
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2 | 3 | ||||||
MIRT120680 | PAK2 | p21 (RAC1) activated kinase 2 | ![]() |
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2 | 2 | ||||||
MIRT117655 | SCAMP4 | secretory carrier membrane protein 4 | ![]() |
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2 | 2 | ||||||
MIRT114923 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT112969 | LUZP1 | leucine zipper protein 1 | ![]() |
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2 | 6 | ||||||
MIRT110051 | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | ![]() |
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2 | 7 | ||||||
MIRT109240 | ZNF275 | zinc finger protein 275 | ![]() |
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2 | 2 | ||||||
MIRT108983 | SLC9A6 | solute carrier family 9 member A6 | ![]() |
1 | 1 | |||||||
MIRT107218 | ZBTB34 | zinc finger and BTB domain containing 34 | ![]() |
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2 | 2 | ||||||
MIRT106733 | RAD23B | RAD23 homolog B, nucleotide excision repair protein | ![]() |
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2 | 3 | ||||||
MIRT106292 | ZFHX4 | zinc finger homeobox 4 | ![]() |
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2 | 6 | ||||||
MIRT104015 | USP42 | ubiquitin specific peptidase 42 | ![]() |
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2 | 6 | ||||||
MIRT103856 | FOXK1 | forkhead box K1 | ![]() |
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2 | 3 | ||||||
MIRT103092 | MAFK | MAF bZIP transcription factor K | ![]() |
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2 | 5 | ||||||
MIRT102971 | EN2 | engrailed homeobox 2 | ![]() |
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2 | 6 | ||||||
MIRT102632 | UBN2 | ubinuclein 2 | ![]() |
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2 | 11 | ||||||
MIRT102434 | CALU | calumenin | ![]() |
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2 | 3 | ||||||
MIRT100896 | CD2AP | CD2 associated protein | ![]() |
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2 | 2 | ||||||
MIRT100566 | PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | ![]() |
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2 | 2 | ||||||
MIRT100364 | HSPA1B | heat shock protein family A (Hsp70) member 1B | ![]() |
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3 | 8 | |||||
MIRT100207 | PPP1R11 | protein phosphatase 1 regulatory inhibitor subunit 11 | ![]() |
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2 | 2 | ||||||
MIRT099631 | E2F3 | E2F transcription factor 3 | ![]() |
1 | 1 | |||||||
MIRT098827 | PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | ![]() |
1 | 1 | |||||||
MIRT096234 | CANX | calnexin | ![]() |
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2 | 2 | ||||||
MIRT093682 | PI4K2B | phosphatidylinositol 4-kinase type 2 beta | ![]() |
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2 | 6 | ||||||
MIRT092209 | BHLHE40 | basic helix-loop-helix family member e40 | ![]() |
1 | 1 | |||||||
MIRT092190 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | ![]() |
1 | 1 | |||||||
MIRT091667 | RARB | retinoic acid receptor beta | ![]() |
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2 | 6 | ||||||
MIRT090688 | U2SURP | U2 snRNP associated SURP domain containing | ![]() |
1 | 1 | |||||||
MIRT090446 | CDV3 | CDV3 homolog | ![]() |
1 | 1 | |||||||
MIRT089206 | ACTR2 | ARP2 actin related protein 2 homolog | ![]() |
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2 | 3 | ||||||
MIRT089105 | B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | ![]() |
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2 | 4 | ||||||
MIRT088102 | SEPT2 | septin 2 | ![]() |
1 | 1 | |||||||
MIRT087554 | YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta | ![]() |
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2 | 2 | ||||||
MIRT087424 | ZNRF3 | zinc and ring finger 3 | ![]() |
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2 | 2 | ||||||
MIRT086005 | UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | ![]() |
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2 | 2 | ||||||
MIRT085215 | CCNT2 | cyclin T2 | ![]() |
1 | 1 | |||||||
MIRT084462 | SOWAHC | sosondowah ankyrin repeat domain family member C | ![]() |
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2 | 4 | ||||||
MIRT083265 | ZCCHC3 | zinc finger CCHC-type containing 3 | ![]() |
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2 | 6 | ||||||
MIRT082985 | PNPLA6 | patatin like phospholipase domain containing 6 | ![]() |
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2 | 2 | ||||||
MIRT080011 | GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | ![]() |
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2 | 4 | ||||||
MIRT079655 | NAPG | NSF attachment protein gamma | ![]() |
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2 | 12 | ||||||
MIRT078282 | RPS6KB1 | ribosomal protein S6 kinase B1 | ![]() |
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2 | 2 | ||||||
MIRT077781 | MINK1 | misshapen like kinase 1 | ![]() |
1 | 1 | |||||||
MIRT076791 | GOSR1 | golgi SNAP receptor complex member 1 | ![]() |
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2 | 2 | ||||||
MIRT075891 | C16ORF72 | chromosome 16 open reading frame 72 | ![]() |
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2 | 7 | ||||||
MIRT075273 | VPS4A | vacuolar protein sorting 4 homolog A | ![]() |
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2 | 8 | ||||||
MIRT075249 | SNTB2 | syntrophin beta 2 | ![]() |
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2 | 4 | ||||||
MIRT074530 | PAGR1 | PAXIP1 associated glutamate rich protein 1 | ![]() |
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2 | 4 | ||||||
MIRT072822 | ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | ![]() |
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2 | 5 | ||||||
MIRT071206 | FCF1 | FCF1, rRNA-processing protein | ![]() |
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2 | 2 | ||||||
MIRT068655 | AKAP11 | A-kinase anchoring protein 11 | ![]() |
1 | 1 | |||||||
MIRT066312 | USP15 | ubiquitin specific peptidase 15 | ![]() |
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2 | 2 | ||||||
MIRT066291 | MTFR1L | mitochondrial fission regulator 1 like | ![]() |
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2 | 2 | ||||||
MIRT065711 | TARBP2 | TARBP2, RISC loading complex RNA binding subunit | ![]() |
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2 | 4 | ||||||
MIRT063394 | ETNK1 | ethanolamine kinase 1 | ![]() |
1 | 1 | |||||||
MIRT061529 | BTG2 | BTG anti-proliferation factor 2 | ![]() |
1 | 1 | |||||||
MIRT061244 | AMOTL1 | angiomotin like 1 | ![]() |
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2 | 12 | ||||||
MIRT061005 | C1ORF21 | chromosome 1 open reading frame 21 | ![]() |
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2 | 6 | ||||||
MIRT057906 | STXBP3 | syntaxin binding protein 3 | ![]() |
1 | 1 | |||||||
MIRT057729 | ZDHHC16 | zinc finger DHHC-type containing 16 | ![]() |
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2 | 2 | ||||||
MIRT057514 | CEP55 | centrosomal protein 55 | ![]() |
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2 | 8 | ||||||
MIRT055811 | PLEKHA1 | pleckstrin homology domain containing A1 | ![]() |
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2 | 2 | ||||||
MIRT055421 | SHOC2 | SHOC2, leucine rich repeat scaffold protein | ![]() |
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2 | 11 | ||||||
MIRT054895 | SOX5 | SRY-box 5 | ![]() |
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2 | 1 | ||||||
MIRT054424 | CARM1 | coactivator associated arginine methyltransferase 1 | ![]() |
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3 | 1 | |||||
MIRT054283 | YAP1 | Yes associated protein 1 | ![]() |
![]() |
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3 | 1 | |||||
MIRT053079 | KLF4 | Kruppel like factor 4 | ![]() |
![]() |
2 | 1 | ||||||
MIRT052930 | REPIN1 | replication initiator 1 | ![]() |
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2 | 1 | ||||||
MIRT051351 | BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | ![]() |
1 | 2 | |||||||
MIRT051350 | TTC1 | tetratricopeptide repeat domain 1 | ![]() |
1 | 1 | |||||||
MIRT051349 | MYBL1 | MYB proto-oncogene like 1 | ![]() |
1 | 1 | |||||||
MIRT051348 | NOP2 | NOP2 nucleolar protein | ![]() |
1 | 1 | |||||||
MIRT051347 | TRIM28 | tripartite motif containing 28 | ![]() |
1 | 1 | |||||||
MIRT051346 | TMEM214 | transmembrane protein 214 | ![]() |
1 | 1 | |||||||
MIRT051345 | FOXO1 | forkhead box O1 | ![]() |
![]() |
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4 | 2 | ||||
MIRT051344 | DSTYK | dual serine/threonine and tyrosine protein kinase | ![]() |
1 | 1 | |||||||
MIRT051343 | PTAR1 | protein prenyltransferase alpha subunit repeat containing 1 | ![]() |
1 | 1 | |||||||
MIRT051342 | SEC63 | SEC63 homolog, protein translocation regulator | ![]() |
1 | 1 | |||||||
MIRT051341 | FASN | fatty acid synthase | ![]() |
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2 | 5 | ||||||
MIRT051340 | CABIN1 | calcineurin binding protein 1 | ![]() |
1 | 1 | |||||||
MIRT051339 | PRDX3 | peroxiredoxin 3 | ![]() |
1 | 1 | |||||||
MIRT051338 | FBXO3 | F-box protein 3 | ![]() |
1 | 1 | |||||||
MIRT051337 | ATP6AP1 | ATPase H+ transporting accessory protein 1 | ![]() |
1 | 1 | |||||||
MIRT051336 | ATF2 | activating transcription factor 2 | ![]() |
1 | 1 | |||||||
MIRT051335 | PSMC4 | proteasome 26S subunit, ATPase 4 | ![]() |
1 | 1 | |||||||
MIRT051334 | MAPK6 | mitogen-activated protein kinase 6 | ![]() |
1 | 1 | |||||||
MIRT051333 | BRWD1 | bromodomain and WD repeat domain containing 1 | ![]() |
1 | 1 | |||||||
MIRT051332 | GDI2 | GDP dissociation inhibitor 2 | ![]() |
1 | 1 | |||||||
MIRT051331 | CLCC1 | chloride channel CLIC like 1 | ![]() |
1 | 1 | |||||||
MIRT051330 | CHD4 | chromodomain helicase DNA binding protein 4 | ![]() |
1 | 1 | |||||||
MIRT051329 | CCT6B | chaperonin containing TCP1 subunit 6B | ![]() |
1 | 1 | |||||||
MIRT051328 | NAB1 | NGFI-A binding protein 1 | ![]() |
1 | 1 | |||||||
MIRT051327 | KIF1A | kinesin family member 1A | ![]() |
1 | 1 | |||||||
MIRT051326 | CNN3 | calponin 3 | ![]() |
1 | 1 | |||||||
MIRT051325 | SNX6 | sorting nexin 6 | ![]() |
1 | 1 | |||||||
MIRT051324 | PDHX | pyruvate dehydrogenase complex component X | ![]() |
1 | 1 | |||||||
MIRT051323 | PREB | prolactin regulatory element binding | ![]() |
1 | 1 | |||||||
MIRT051322 | RGPD5 | RANBP2-like and GRIP domain containing 5 | ![]() |
1 | 1 | |||||||
MIRT051321 | CCNYL1 | cyclin Y like 1 | ![]() |
1 | 1 | |||||||
MIRT051320 | ASNSD1 | asparagine synthetase domain containing 1 | ![]() |
1 | 1 | |||||||
MIRT051319 | RPP30 | ribonuclease P/MRP subunit p30 | ![]() |
1 | 1 | |||||||
MIRT051318 | CALD1 | caldesmon 1 | ![]() |
1 | 1 | |||||||
MIRT051317 | ODC1 | ornithine decarboxylase 1 | ![]() |
1 | 1 | |||||||
MIRT051316 | HIST1H2BK | histone cluster 1 H2B family member k | ![]() |
1 | 1 | |||||||
MIRT051315 | PCF11 | PCF11 cleavage and polyadenylation factor subunit | ![]() |
1 | 1 | |||||||
MIRT051314 | GCLM | glutamate-cysteine ligase modifier subunit | ![]() |
1 | 1 | |||||||
MIRT051313 | IKBKG | inhibitor of nuclear factor kappa B kinase subunit gamma | ![]() |
1 | 1 | |||||||
MIRT051312 | ACVR1B | activin A receptor type 1B | ![]() |
1 | 1 | |||||||
MIRT051311 | PLA2G2D | phospholipase A2 group IID | ![]() |
1 | 1 | |||||||
MIRT032077 | DLK1 | delta like non-canonical Notch ligand 1 | ![]() |
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2 | 1 | ||||||
MIRT007090 | RECK | reversion inducing cysteine rich protein with kazal motifs | ![]() |
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4 | 3 | ||||
MIRT006998 | PURA | purine rich element binding protein A | ![]() |
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2 | 2 | ||||||
MIRT006913 | IFNG | interferon gamma | ![]() |
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2 | 1 | ||||||
MIRT006805 | HMGA2 | high mobility group AT-hook 2 | ![]() |
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3 | 1 | |||||
MIRT006801 | HMGA1 | high mobility group AT-hook 1 | ![]() |
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4 | 2 | ||||
MIRT006658 | Ccnd1 | cyclin D1 | ![]() |
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2 | 2 | ||||||
MIRT006181 | MN1 | MN1 proto-oncogene, transcriptional regulator | ![]() |
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4 | 1 | ||||
MIRT006177 | CRKL | CRK like proto-oncogene, adaptor protein | ![]() |
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6 | 3 | ||
MIRT006176 | CLCN3 | chloride voltage-gated channel 3 | ![]() |
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4 | 1 | ||||
MIRT006027 | FGF7 | fibroblast growth factor 7 | ![]() |
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2 | 1 | ||||||
MIRT005763 | TP53 | tumor protein p53 | ![]() |
1 | 1 | |||||||
MIRT005552 | CHUK | conserved helix-loop-helix ubiquitous kinase | ![]() |
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4 | 1 | ||||
MIRT004829 | NFKB1 | nuclear factor kappa B subunit 1 | ![]() |
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3 | 1 | |||||
MIRT004680 | TSPYL2 | TSPY like 2 | ![]() |
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2 | 1 | ||||||
MIRT004275 | VEGFA | vascular endothelial growth factor A | ![]() |
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7 | 17 | |
MIRT004046 | UCP2 | uncoupling protein 2 | ![]() |
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3 | 1 | |||||
MIRT003899 | APP | amyloid beta precursor protein | ![]() |
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4 | 3 | ||||
MIRT003891 | TMEM184B | transmembrane protein 184B | ![]() |
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2 | 1 | ||||||
MIRT003888 | CADM1 | cell adhesion molecule 1 | ![]() |
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3 | 1 | |||||
MIRT003887 | ANAPC16 | anaphase promoting complex subunit 16 | ![]() |
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2 | 1 | ||||||
MIRT003886 | TRMT13 | tRNA methyltransferase 13 homolog | ![]() |
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2 | 1 | ||||||
MIRT003885 | NIPAL2 | NIPA like domain containing 2 | ![]() |
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2 | 1 | ||||||
MIRT003884 | C4orf27 | histone PARylation factor 1 | ![]() |
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2 | 1 | ||||||
MIRT003883 | C2orf43 | lipid droplet associated hydrolase | ![]() |
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2 | 1 | ||||||
MIRT003882 | CCDC111 | primase and DNA directed polymerase | ![]() |
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2 | 1 | ||||||
MIRT003881 | C17orf80 | chromosome 17 open reading frame 80 | ![]() |
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2 | 1 | ||||||
MIRT003880 | PWWP2A | PWWP domain containing 2A | ![]() |
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2 | 1 | ||||||
MIRT003879 | FAM122C | family with sequence similarity 122C | ![]() |
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2 | 1 | ||||||
MIRT003878 | C2orf74 | chromosome 2 open reading frame 74 | ![]() |
1 | 1 | |||||||
MIRT003877 | FAM69A | family with sequence similarity 69 member A | ![]() |
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2 | 1 | ||||||
MIRT003876 | NT5DC1 | 5'-nucleotidase domain containing 1 | ![]() |
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2 | 1 | ||||||
MIRT003875 | SKAP2 | src kinase associated phosphoprotein 2 | ![]() |
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3 | 1 | |||||
MIRT003874 | HSP90B1 | heat shock protein 90 beta family member 1 | ![]() |
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2 | 1 | ||||||
MIRT003873 | VPS45 | vacuolar protein sorting 45 homolog | ![]() |
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2 | 1 | ||||||
MIRT003872 | WIPF1 | WAS/WASL interacting protein family member 1 | ![]() |
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2 | 1 | ||||||
MIRT003334 | AKT3 | AKT serine/threonine kinase 3 | ![]() |
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3 | 6 | |||||
MIRT003333 | BRCA1 | BRCA1, DNA repair associated | ![]() |
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2 | 2 | ||||||
MIRT003330 | RPS6 | ribosomal protein S6 | 0 | 1 | ||||||||
MIRT002946 | DMTF1 | cyclin D binding myb like transcription factor 1 | ![]() |
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4 | 4 | ||||
MIRT001802 | BACE1 | beta-secretase 1 | ![]() |
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2 | 1 | ||||||
MIRT001228 | CCNE1 | cyclin E1 | ![]() |
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7 | 10 | |
MIRT001227 | CCND1 | cyclin D1 | ![]() |
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6 | 8 | ||
MIRT000922 | ZNF559 | zinc finger protein 559 | ![]() |
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2 | 1 | ||||||
MIRT000916 | UGP2 | UDP-glucose pyrophosphorylase 2 | ![]() |
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2 | 1 | ||||||
MIRT000914 | UGDH | UDP-glucose 6-dehydrogenase | ![]() |
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2 | 1 | ||||||
MIRT000910 | TIA1 | TIA1 cytotoxic granule associated RNA binding protein | ![]() |
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2 | 1 | ||||||
MIRT000908 | SLC35B3 | solute carrier family 35 member B3 | ![]() |
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2 | 1 | ||||||
MIRT000906 | SLC35A1 | solute carrier family 35 member A1 | ![]() |
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2 | 1 | ||||||
MIRT000902 | RNASEL | ribonuclease L | ![]() |
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2 | 1 | ||||||
MIRT000900 | RHOT1 | ras homolog family member T1 | ![]() |
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2 | 1 | ||||||
MIRT000898 | RAD51C | RAD51 paralog C | ![]() |
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2 | 1 | ||||||
MIRT000896 | PRIM1 | DNA primase subunit 1 | ![]() |
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2 | 1 | ||||||
MIRT000894 | PNN | pinin, desmosome associated protein | ![]() |
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2 | 1 | ||||||
MIRT000892 | PMS1 | PMS1 homolog 1, mismatch repair system component | ![]() |
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2 | 1 | ||||||
MIRT000890 | PHKB | phosphorylase kinase regulatory subunit beta | ![]() |
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2 | 1 | ||||||
MIRT000888 | PDCD6IP | programmed cell death 6 interacting protein | ![]() |
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2 | 1 | ||||||
MIRT000886 | OSGEPL1 | O-sialoglycoprotein endopeptidase like 1 | ![]() |
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2 | 1 | ||||||
MIRT000884 | OMA1 | OMA1 zinc metallopeptidase | ![]() |
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2 | 1 | ||||||
MIRT000880 | MSH2 | mutS homolog 2 | ![]() |
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2 | 1 | ||||||
MIRT000878 | MCL1 | MCL1, BCL2 family apoptosis regulator | ![]() |
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2 | 1 | ||||||
MIRT000868 | JUN | Jun proto-oncogene, AP-1 transcription factor subunit | ![]() |
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2 | 1 | ||||||
MIRT000866 | HSPA1A | heat shock protein family A (Hsp70) member 1A | ![]() |
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2 | 1 | ||||||
MIRT000865 | HSDL2 | hydroxysteroid dehydrogenase like 2 | ![]() |
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2 | 1 | ||||||
MIRT000863 | HRSP12 | reactive intermediate imine deaminase A homolog | ![]() |
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2 | 1 | ||||||
MIRT000859 | HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | ![]() |
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2 | 1 | ||||||
MIRT000857 | HDHD2 | haloacid dehalogenase like hydrolase domain containing 2 | ![]() |
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2 | 1 | ||||||
MIRT000855 | HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | ![]() |
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2 | 1 | ||||||
MIRT000853 | H3F3B | H3 histone family member 3B | ![]() |
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2 | 1 | ||||||
MIRT000851 | GTF2H1 | general transcription factor IIH subunit 1 | ![]() |
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2 | 1 | ||||||
MIRT000849 | GOLPH3L | golgi phosphoprotein 3 like | ![]() |
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2 | 1 | ||||||
MIRT000847 | GOLGA5 | golgin A5 | ![]() |
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2 | 1 | ||||||
MIRT000835 | ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | ![]() |
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2 | 1 | ||||||
MIRT000833 | CREBL2 | cAMP responsive element binding protein like 2 | ![]() |
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4 | 5 | ||||
MIRT000831 | CEP63 | centrosomal protein 63 | ![]() |
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2 | 1 | ||||||
MIRT000829 | CENPJ | centromere protein J | ![]() |
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2 | 1 | ||||||
MIRT000827 | CDC14B | cell division cycle 14B | ![]() |
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2 | 1 | ||||||
MIRT000825 | CARD8 | caspase recruitment domain family member 8 | ![]() |
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2 | 1 | ||||||
MIRT000823 | TMEM251 | transmembrane protein 251 | ![]() |
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2 | 1 | ||||||
MIRT000819 | ASXL2 | additional sex combs like 2, transcriptional regulator | ![]() |
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2 | 1 | ||||||
MIRT000817 | WT1 | Wilms tumor 1 | ![]() |
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2 | 1 | ||||||
MIRT000815 | BCL2 | BCL2, apoptosis regulator | ![]() |
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6 | 13 | ||
MIRT000812 | RAB21 | RAB21, member RAS oncogene family | ![]() |
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2 | 1 | ||||||
MIRT000810 | PDCD4 | programmed cell death 4 | ![]() |
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3 | 2 | |||||
MIRT000808 | TPI1 | triosephosphate isomerase 1 | ![]() |
1 | 1 | |||||||
MIRT000806 | ACTR1A | ARP1 actin related protein 1 homolog A | ![]() |
1 | 1 | |||||||
MIRT000804 | RAB9B | RAB9B, member RAS oncogene family | ![]() |
1 | 1 | |||||||
MIRT000285 | CCND2 | cyclin D2 | ![]() |
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4 | 7 | ||||
MIRT000284 | CDC25A | cell division cycle 25A | ![]() |
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4 | 4 | ||||
MIRT000283 | MYB | MYB proto-oncogene, transcription factor | ![]() |
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5 | 3 | |||
MIRT000282 | WNT3A | Wnt family member 3A | ![]() |
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3 | 2 | |||||
MIRT000280 | BMI1 | BMI1 proto-oncogene, polycomb ring finger | ![]() |
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5 | 3 |