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miRTarBase - #MIRT003087 -
pre-miRNA Information
pre-miRNA hsa-mir-122   
Genomic Coordinates chr18: 58451074 - 58451158
Synonyms MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, MIR122
Description Homo sapiens miR-122 stem-loop
Comment The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-122-5p
Sequence 15| UGGAGUGUGACAAUGGUGUUUG |36
Evidence Experimental
Experiments Cloned
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 18 + 58451091 29233923 MiREDiBase
C-to-U 11 18 + 58451098 28550310 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1258166649 1 dbSNP
rs1426570658 6 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles

Circulating MicroRNA Expression Profiling
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RAB11FIP1   
Synonyms NOEL1A, RCP, rab11-FIP1
Description RAB11 family interacting protein 1
Transcript NM_001002814   
Other Transcripts NM_025151   
Expression
Putative miRNA Targets on RAB11FIP1
3'UTR of RAB11FIP1
(miRNA target sites are highlighted)		 
>RAB11FIP1|NM_001002814|3'UTR
   1 ATCAGCAGAAAAAAAACACCGAGACGTTTCTGTGACTTCACTTTCACCTGCTCCAGGGGTCAAGGACTTGCCTTGCCTGA
  81 TAACCAGCCAGCAGGCTCCGAATCACCATCTCCCTCACATGTTATCCGGCAAGAGTGAATTCTACCAATGGAAGCCAGGT
 161 TAATGATTACAATTAATCTTTTACTGTACATTCCCAAGGCTTTAGTTTTAAATGCCACTGTGCCTTTAACAAGGTTGTAA
 241 ATATTTTATGCCCACCAGAGATGTGGTCATAAGATCTGATCCTGAGCCAGAGATTCAGATGGCACAGGAAGTATTCATGT
 321 ATTTTAACACTGGGGTTTTCTTTCTTTCATACTGAGATTTTTTTTCAGTATGTATCCTCCAGCTCTTAAAGCTTACCTGA
 401 GAAAGCTTTAAATGAGAAAAGGACCATGCGATTGGTGCTGTGTTACATACACATACTTTCTTGGCTTCTGAGTAGCTCAG
 481 GTGTGGCTTTTGGCTGCAGATGTTAAATTTTGATACCATGTAAACCTACCCAGCTTCTCAGACTTGGGTCTTGTTTTTTG
 561 ATGGGAACAGAGGTGTTTAGAGAAAGCCTCTGAGTATGCCTTTCAGATTTTGAACAAGCGGCCTTTTCTAAACATCGACT
 641 TCTACTACTCTCTAGCCTTAAAATACCTTCTGCTTAGATCCAGGGCCCTTCTACTGGAGATAGGAAAAGTAGAATTCAGG
 721 AATTAAAAGAATTACTCTTTATTCAATTTGAGGAACTTGGTGAAAGCCCCTCCTCTTATGACAGCCAGGTTCCTGCTGGC
 801 TAGACCAGCCTATTCAGCGCTTTGCTAGGGGATTGGGTGGTCCACGCACTCGCTAATACAGTTCTCCAGGTGTGGAATGA
 881 TGTCAATACGATTGCTTGGCCTTTTCCCCCTGTGCCTTTGCTCGGTGCTCTGGTTTCCTCAGCAACACTCCTTGTAAGGG
 961 GCAGAGACAGGGTCCACCAACTCCCCAAGATGAAGAAGCCCCTTCAGGCCAGTCGTGGTGGCTCATGCCTGTAATCCCAG
1041 CACTTTGCAAGGCCGAGGAGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGCGAAACCCCATC
1121 TCTACTAAAAATACAAAAATTAGCTTGGCATGGTGGTGCGTGCCTGTAATCCCAGCTACTCGGGAGGCTGGGGCAGGAGA
1201 ATTGCTTGAACTTGGGAGATGGAGGCTGCAGCGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAAGAGTTTTTTTA
1281 AGACTCTTAAAAAAAGAGCCTGGGCAATTTTTTTAAGACTCTGTCTTAAAAAAAACTAAAAAGAAAAAAAGAAGCCCCTT
1361 CACTCTACAGGGGACAGGAGACCATGGATTGGACCCCAAAGGGATTGAACTGCATCTGCATGTCTGTCCTTTGAACACTT
1441 TCTCTCCCTGCCCAAAAGGAAACCCAAATTATTTGTGGGATACTGGGGAAATTGTAGTGAAGGGCTTAATGTAGTTAATA
1521 AAAGTTAAAAGTCAGTAGAAAACAGGTGCCTCAGCCTTCAAATGGTTGCTTTTTTTCCATTTTCCCTCATGAATAGACTC
1601 ACCAGCATTTTACCCCCTTGTTATAAAACTGTGCAGAGCAAGAAGATGATACTTATTTTTGAATTTGTATTTTTAAAACT
1681 AGATTTATAGACTTTTTTTTTTTTTAACTAGGGCACTTGCTTCCTTCTTAGCTAAAAGCACCAGCTGAGATTTTTCAGGT
1761 AATTTTGTTGTTACTCACTTAAGACTGGAATTAGAATGTTTCTGGTATTTCTCATTTTTTTCCCTGGCTATGATAGAATC
1841 TCATCTAATCTTGACATCTCTCCTAGGGGAAGAATATCACAGGCTAATAGCGTGGTTGGGGGTGAAGATGATAGCAGTTA
1921 TTAAATCAGGAATCTCTTTTATGTGTGTCCTTGTTACATTGAGGTTAAGAGACAAAATCATTGGCAGTGCAATCTCTTTC
2001 CAGGATTTCGTTTGCTGTGGCATTGGTTATATCAGAGCACTTTAATCTGAAGGATGATACTGTAACTTGATTTATCTAAT
2081 TAGCTTTTAATTATCTACAGCTATTTTATTTTATTTAATTCTCTCCTACAGTACTGGGACCACTGTAAACTTCTCAGATG
2161 ACTTGTATTTTTGTAGTGCTATGAAATTTATTTACATACTTATAAAGAAAACTGTATGTTCACTTGAACTCTGAAAATGT
2241 ACATGTATGGCTGGACGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGAATCACTTGATTGA
2321 GGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAAAATACAGAAATTAGCTGGGTGTGG
2401 TGGCAGACAGCTGTAATCTCAGCTGCTCGGGAGGCTGAGGCACAAGAATCGCTTGAGCCAGGGAGGTGGAGGTTGCAGTG
2481 AGCTGAGATCACATCATTGCACTCCAGCCTGGGCAACGGGCGAGACTCTGTCTCAAAAAAAAGAAAGAAAGAAAAGGTAC
2561 ATGTATATATTTGTCCTGCATTATGTTTTTTACTTGATATAAATGTATTTTTACTGTGATAGTCCAAGTGCCCTGGGGGG
2641 CAGGTGTGCTCTATGTGGTTCTTCTTCCATTGGAGAGCTGGCGTAGAGATCTGCAGTGTTCACAAGGATGTTGGTTTGGA
2721 GATGTCTGCTGCTAGGACCTGGGGTGTGTGACTCAGTCCATATGAGAGGGACATCTGGGTGGAGGAGTAAATTCCTGTGC
2801 TCTGAAATGCCACTTGGTAGCTCTGGACAATGAAGGACAATTGACTCAAGGGTGCCTGGCTTCTGCTGCTGCTGGGAAAA
2881 AATTCAGTTTATAGCATTCCTGCACCTCCCAAAGTAGATAACCTGGAGGTCATTCAGTTAACAACTGTCCCTGAGGACTC
2961 AGTTTTGGGGGAGGGGTTATCTGGGAGAAGCTTTAGCCTGTTCTGAGCCATTAGGAGACATTAGTGAATTGGAGCACTGG
3041 AGAATCCTACAAATGGCCTATGTCTCAGAAGAGCTGGGACCTCCTTCCAGCTGCTGCAGATGCTGACAGGCCCTGGGAGG
3121 CTGCTGTGCTCTGGAGAAGCTGGAGCAGCTCATTTCTTGGCCTAGCCTGGCTGCCTCAGAAAGAGCAGTCAGGACTTGAG
3201 GGAAGCATCAAATTCTATACCCATAAACTGCAGTTGGAAGTCAGCTTTTTGAAATGTCCAGCCTTTGCCCAATTGTTTCA
3281 GATCATCTCATGCCTCAGGCTTTGGCAGGTATCCTGCCCTCCATCTTATTCCAGTGTGTTCACCTCATCAAGGCAGCAGA
3361 GTGGATGAAGGAGTAAGTCTGCCCTTTGCCATACTGAACAGCTGTGGACCCCGATTGGTGAGGGCTCTGCATATGCCTGT
3441 ATGAAGGAGATACAGGTGTGTGTGCACATGCCGGTATGAAGAAGACACAGGCATGTGCTTCTCAGTTTTGCTAACAGTGG
3521 GAGCTCAACGGGGCAGAGGGAGGAAGGTCCATGATGCTCAGCCACATACTGTAGAGAGAGGCAATTTAATGTTAAATGAC
3601 GCACCATCCTCCCTCCCACCCTTCTCCCAGTCAACTTTTTTTCTTTTTCTAGAACTACTAATTATCTCTCAAGGCTGAAA
3681 AATTAATTGCCTTAGGTGGAGAACTTAATTCCTAGTATCCACCAAACTTAACTCCGTATCTCCATATGGTGTCTCCATAT
3761 CTACTGTGTGAGCTACTTAACTGACGCCCTCTTCCTCCAACTGAAGGATCGCCCAACGTTTTTGGATTATAGAATTATTA
3841 TTTCCTGCTTTCTTTCTTTGGGACTTTTGAATTTCTTTGGTTTCGTTTTTAAGAAGTAACCCAACATTTCCTACAACACT
3921 AAATAAAATGGTACTTACCTTTCAAAGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions (Predicted by miRanda)
IDDuplex structurePositionScoreMFE
1 
miRNA  3' guuUGUGGUAACAGUGUGAGGu 5'
             |||:||||   :|||||| 
Target 5' atcACATCATT---GCACTCCa 3'
 		2488 - 2506 148.00 -20.10
2 
miRNA  3' guuuGUGGUAACAGUGUGAGGu 5'
              | :||  |  ||||||| 
Target 5' gtttCCTCA--GCAACACTCCt 3'
 		933 - 952 142.00 -12.20
3 
miRNA  3' guuuguGGUAACAGUGUGAGGu 5'
                ::| ||| |||:||| 
Target 5' aatcttTTACTGT-ACATTCCc 3'
 		175 - 195 135.00 -8.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30155141 3 COSMIC
COSN2531325 8 COSMIC
COSN26991252 9 COSMIC
COSN31601560 12 COSMIC
COSN32053186 45 COSMIC
COSN30184655 48 COSMIC
COSN31508491 53 COSMIC
COSN30496455 54 COSMIC
COSN30454619 57 COSMIC
COSN30127604 91 COSMIC
COSN32053387 94 COSMIC
COSN31540429 96 COSMIC
COSN9633985 102 COSMIC
COSN30125919 121 COSMIC
COSN30477816 126 COSMIC
COSN23521587 177 COSMIC
COSN31604971 178 COSMIC
COSN30130921 238 COSMIC
COSN26538045 287 COSMIC
COSN28665954 496 COSMIC
COSN27884021 619 COSMIC
COSN8083300 845 COSMIC
COSN26645843 1267 COSMIC
COSN30696077 1288 COSMIC
COSN30551869 1308 COSMIC
COSN31606126 1423 COSMIC
COSN30175492 1459 COSMIC
COSN28860360 1463 COSMIC
COSN18749506 1693 COSMIC
COSN9633984 1696 COSMIC
COSN26415122 1805 COSMIC
COSN31561414 1892 COSMIC
COSN9633983 1910 COSMIC
COSN19663760 1937 COSMIC
COSN31534983 2009 COSMIC
COSN31516797 2121 COSMIC
COSN31516247 2134 COSMIC
COSN20947361 2306 COSMIC
COSN31523997 2618 COSMIC
COSN30173888 2651 COSMIC
COSN31523546 2918 COSMIC
COSN31532136 2951 COSMIC
COSN22028819 3053 COSMIC
COSN17076080 3615 COSMIC
COSN17076079 3753 COSMIC
COSN27099496 3831 COSMIC
COSN21420088 4051 COSMIC
COSN21474019 4204 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1470588864 2 dbSNP
rs767929651 3 dbSNP
rs1174331540 5 dbSNP
rs1432971309 6 dbSNP
rs755500140 8 dbSNP
rs751151910 9 dbSNP
rs1447943083 12 dbSNP
rs1389598430 13 dbSNP
rs1469356807 14 dbSNP
rs765961978 16 dbSNP
rs762764236 17 dbSNP
rs768132133 17 dbSNP
rs778506557 17 dbSNP
rs772748544 18 dbSNP
rs748948361 19 dbSNP
rs771529024 20 dbSNP
rs1156321069 21 dbSNP
rs750295322 21 dbSNP
rs779916890 21 dbSNP
rs201814791 25 dbSNP
rs776448220 26 dbSNP
rs768621870 31 dbSNP
rs918286144 34 dbSNP
rs746927581 39 dbSNP
rs1334972343 40 dbSNP
rs1230127027 41 dbSNP
rs1362676433 45 dbSNP
rs1236565203 46 dbSNP
rs1008368001 47 dbSNP
rs1329352261 53 dbSNP
rs528549475 57 dbSNP
rs1260777715 59 dbSNP
rs868749900 71 dbSNP
rs1009225141 80 dbSNP
rs747801928 88 dbSNP
rs778476914 91 dbSNP
rs570861909 95 dbSNP
rs1417733189 97 dbSNP
rs985310097 99 dbSNP
rs1412989176 100 dbSNP
rs552151281 103 dbSNP
rs193169185 116 dbSNP
rs74817207 127 dbSNP
rs73673896 128 dbSNP
rs1303390819 130 dbSNP
rs967404150 134 dbSNP
rs749144512 139 dbSNP
rs949164705 144 dbSNP
rs908667790 166 dbSNP
rs1350878635 175 dbSNP
rs1475462151 186 dbSNP
rs78217766 208 dbSNP
rs893406627 216 dbSNP
rs1210154936 228 dbSNP
rs527422569 229 dbSNP
rs779864133 234 dbSNP
rs1207919111 251 dbSNP
rs1435370450 253 dbSNP
rs919907084 255 dbSNP
rs1001716035 256 dbSNP
rs559865451 261 dbSNP
rs1222214990 264 dbSNP
rs964661157 266 dbSNP
rs907396759 268 dbSNP
rs1196536738 277 dbSNP
rs912781713 282 dbSNP
rs1249640045 286 dbSNP
rs1371395640 287 dbSNP
rs1427814632 288 dbSNP
rs1045483358 290 dbSNP
rs370902261 295 dbSNP
rs1404057151 299 dbSNP
rs1291458087 300 dbSNP
rs1225216314 305 dbSNP
rs541276711 306 dbSNP
rs1369199242 310 dbSNP
rs929739137 312 dbSNP
rs967514570 318 dbSNP
rs1294300845 326 dbSNP
rs1347288332 328 dbSNP
rs1305227575 334 dbSNP
rs1283761198 339 dbSNP
rs1275913188 348 dbSNP
rs1404094704 351 dbSNP
rs896804646 355 dbSNP
rs1009256044 356 dbSNP
rs1248688880 357 dbSNP
rs1488964498 361 dbSNP
rs1038053882 366 dbSNP
rs1186140263 366 dbSNP
rs941236289 373 dbSNP
rs1451381033 374 dbSNP
rs1170434003 375 dbSNP
rs1390668433 381 dbSNP
rs1423770948 398 dbSNP
rs1162360861 399 dbSNP
rs1309476749 411 dbSNP
rs1351390755 412 dbSNP
rs1436806475 423 dbSNP
rs1287902959 424 dbSNP
rs757595888 429 dbSNP
rs572847306 430 dbSNP
rs1165623833 444 dbSNP
rs1382619863 452 dbSNP
rs1001848433 457 dbSNP
rs933834213 461 dbSNP
rs1322661429 464 dbSNP
rs1215393430 475 dbSNP
rs922470020 477 dbSNP
rs905115480 497 dbSNP
rs2411200 499 dbSNP
rs1189222464 510 dbSNP
rs976176581 520 dbSNP
rs557928781 529 dbSNP
rs1020216355 530 dbSNP
rs1199260638 532 dbSNP
rs990110827 537 dbSNP
rs2411201 541 dbSNP
rs886928591 548 dbSNP
rs1415759462 554 dbSNP
rs957582213 555 dbSNP
rs1157958088 566 dbSNP
rs1047202345 571 dbSNP
rs1458374743 572 dbSNP
rs931404916 586 dbSNP
rs1381400756 587 dbSNP
rs1446509937 596 dbSNP
rs1034554606 599 dbSNP
rs1380373910 612 dbSNP
rs919995418 619 dbSNP
rs1331414189 622 dbSNP
rs1209580082 625 dbSNP
rs1182831389 628 dbSNP
rs1460020659 634 dbSNP
rs1437440802 636 dbSNP
rs1420250681 637 dbSNP
rs1239091582 644 dbSNP
rs1271019763 646 dbSNP
rs1176359349 650 dbSNP
rs747760244 650 dbSNP
rs1409474440 655 dbSNP
rs1473409064 658 dbSNP
rs1040119661 661 dbSNP
rs1159409249 663 dbSNP
rs1002232094 665 dbSNP
rs942679613 670 dbSNP
rs1412216217 673 dbSNP
rs912843964 674 dbSNP
rs1441950317 675 dbSNP
rs1306627558 678 dbSNP
rs1352708424 680 dbSNP
rs1325654794 683 dbSNP
rs987060764 685 dbSNP
rs1222746325 686 dbSNP
rs571652529 687 dbSNP
rs1262599256 691 dbSNP
rs1442996190 699 dbSNP
rs990253669 701 dbSNP
rs1024921446 703 dbSNP
rs1281020369 710 dbSNP
rs1483899337 716 dbSNP
rs993903033 732 dbSNP
rs1428111709 755 dbSNP
rs1032055689 756 dbSNP
rs1334802569 762 dbSNP
rs142733672 764 dbSNP
rs560214309 767 dbSNP
rs1406098043 773 dbSNP
rs1306680502 774 dbSNP
rs941013454 775 dbSNP
rs1176376808 777 dbSNP
rs1468654518 782 dbSNP
rs1372822902 798 dbSNP
rs1414718190 799 dbSNP
rs557271301 806 dbSNP
rs188608371 809 dbSNP
rs568279316 812 dbSNP
rs933928029 818 dbSNP
rs922449247 819 dbSNP
rs1338794862 827 dbSNP
rs1227638453 834 dbSNP
rs1272322882 836 dbSNP
rs541488455 841 dbSNP
rs1205519452 843 dbSNP
rs553086121 845 dbSNP
rs183244246 846 dbSNP
rs574299676 847 dbSNP
rs913325354 851 dbSNP
rs990225805 852 dbSNP
rs1242564196 854 dbSNP
rs957363746 865 dbSNP
rs544944251 871 dbSNP
rs1459905558 875 dbSNP
rs980366603 879 dbSNP
rs1039789069 880 dbSNP
rs1324432502 882 dbSNP
rs1286171518 883 dbSNP
rs942727556 886 dbSNP
rs891113677 889 dbSNP
rs1277418599 890 dbSNP
rs1229036736 897 dbSNP
rs1264711151 898 dbSNP
rs1353951193 899 dbSNP
rs972068330 900 dbSNP
rs1382915975 904 dbSNP
rs552288191 910 dbSNP
rs1290100732 911 dbSNP
rs1024451984 923 dbSNP
rs1051309012 924 dbSNP
rs1249332053 925 dbSNP
rs1450715345 929 dbSNP
rs192690989 930 dbSNP
rs1187427169 932 dbSNP
rs1367140729 942 dbSNP
rs946318038 953 dbSNP
rs1347458543 954 dbSNP
rs1384439940 955 dbSNP
rs994747098 960 dbSNP
rs756032268 962 dbSNP
rs1455719794 970 dbSNP
rs961081879 971 dbSNP
rs1322707919 973 dbSNP
rs148898575 975 dbSNP
rs1435774827 988 dbSNP
rs562293607 1005 dbSNP
rs376713254 1007 dbSNP
rs544144122 1010 dbSNP
rs147831433 1014 dbSNP
rs1284440354 1015 dbSNP
rs1206434660 1017 dbSNP
rs1269521393 1018 dbSNP
rs1464943038 1019 dbSNP
rs1200411275 1024 dbSNP
rs998086367 1025 dbSNP
rs901086974 1026 dbSNP
rs980534927 1029 dbSNP
rs1384736138 1030 dbSNP
rs1042187802 1031 dbSNP
rs1471771337 1032 dbSNP
rs969485336 1033 dbSNP
rs945201263 1038 dbSNP
rs1459973336 1042 dbSNP
rs1412854859 1048 dbSNP
rs1469310707 1049 dbSNP
rs1302199033 1051 dbSNP
rs1243793034 1053 dbSNP
rs915112797 1054 dbSNP
rs370584619 1055 dbSNP
rs577883708 1059 dbSNP
rs1349621556 1061 dbSNP
rs1289782903 1065 dbSNP
rs375257916 1068 dbSNP
rs1231798765 1070 dbSNP
rs1359672510 1073 dbSNP
rs927268292 1073 dbSNP
rs1201521280 1078 dbSNP
rs1024661338 1079 dbSNP
rs879527388 1082 dbSNP
rs1482265733 1086 dbSNP
rs144380138 1087 dbSNP
rs558719095 1089 dbSNP
rs1432688401 1100 dbSNP
rs1137155 1102 dbSNP
rs764479149 1106 dbSNP
rs547965340 1109 dbSNP
rs186623218 1110 dbSNP
rs995380490 1115 dbSNP
rs1369748080 1117 dbSNP
rs1137156 1118 dbSNP
rs1407725795 1120 dbSNP
rs1309476959 1121 dbSNP
rs112555767 1124 dbSNP
rs1385858937 1131 dbSNP
rs112142124 1134 dbSNP
rs564152109 1141 dbSNP
rs1018802363 1143 dbSNP
rs953790590 1146 dbSNP
rs1006955154 1151 dbSNP
rs1340519349 1156 dbSNP
rs545942111 1159 dbSNP
rs1027967268 1160 dbSNP
rs540603062 1163 dbSNP
rs1305313722 1166 dbSNP
rs1189662470 1167 dbSNP
rs891179408 1177 dbSNP
rs540830085 1179 dbSNP
rs900869580 1181 dbSNP
rs1161844893 1182 dbSNP
rs1430391492 1187 dbSNP
rs1042692031 1191 dbSNP
rs1389410891 1198 dbSNP
rs1009460755 1204 dbSNP
rs893627323 1212 dbSNP
rs1178949443 1216 dbSNP
rs1381887402 1218 dbSNP
rs774473467 1220 dbSNP
rs563239856 1221 dbSNP
rs770993206 1223 dbSNP
rs1355451900 1226 dbSNP
rs1482137146 1229 dbSNP
rs541468937 1232 dbSNP
rs182314147 1233 dbSNP
rs1444379600 1234 dbSNP
rs1389844930 1237 dbSNP
rs1164229231 1238 dbSNP
rs190026258 1241 dbSNP
rs573129020 1243 dbSNP
rs576993327 1244 dbSNP
rs947843176 1246 dbSNP
rs1275850386 1254 dbSNP
rs1321473855 1257 dbSNP
rs1233242838 1258 dbSNP
rs972963928 1260 dbSNP
rs111559209 1261 dbSNP
rs991829147 1265 dbSNP
rs1339566649 1274 dbSNP
rs1273475454 1279 dbSNP
rs1246017713 1280 dbSNP
rs111410466 1286 dbSNP
rs1310012652 1296 dbSNP
rs1227153432 1301 dbSNP
rs951026050 1303 dbSNP
rs1374779015 1308 dbSNP
rs752096250 1310 dbSNP
rs1408398477 1312 dbSNP
rs1422975928 1313 dbSNP
rs1370145860 1314 dbSNP
rs1448218835 1317 dbSNP
rs1164478325 1320 dbSNP
rs1318203610 1321 dbSNP
rs1351191891 1323 dbSNP
rs1459685233 1329 dbSNP
rs1461628495 1335 dbSNP
rs780962572 1336 dbSNP
rs918543031 1336 dbSNP
rs1366762982 1339 dbSNP
rs558354807 1343 dbSNP
rs1164258510 1345 dbSNP
rs754723072 1346 dbSNP
rs973972023 1346 dbSNP
rs1423164762 1347 dbSNP
rs1412642463 1350 dbSNP
rs962883981 1351 dbSNP
rs1481966972 1355 dbSNP
rs780644918 1358 dbSNP
rs1222738797 1362 dbSNP
rs1489278771 1370 dbSNP
rs1018122670 1372 dbSNP
rs771581756 1374 dbSNP
rs984309148 1375 dbSNP
rs1263161642 1376 dbSNP
rs1243502728 1378 dbSNP
rs1317984571 1386 dbSNP
rs1290759132 1387 dbSNP
rs1007104649 1389 dbSNP
rs1266357846 1395 dbSNP
rs1466289000 1396 dbSNP
rs774004854 1397 dbSNP
rs955491483 1400 dbSNP
rs1242588506 1404 dbSNP
rs1482807823 1407 dbSNP
rs1179841898 1414 dbSNP
rs953739955 1420 dbSNP
rs1029662550 1421 dbSNP
rs1157931682 1422 dbSNP
rs73598921 1437 dbSNP
rs891789031 1443 dbSNP
rs761368995 1444 dbSNP
rs1169789297 1471 dbSNP
rs1000472151 1473 dbSNP
rs569826288 1488 dbSNP
rs1409375094 1492 dbSNP
rs965396391 1497 dbSNP
rs549740677 1498 dbSNP
rs1421375210 1518 dbSNP
rs7003704 1519 dbSNP
rs1480642363 1521 dbSNP
rs77766600 1524 dbSNP
rs1286630376 1531 dbSNP
rs950226137 1555 dbSNP
rs1331353684 1559 dbSNP
rs1189120194 1565 dbSNP
rs1224344225 1565 dbSNP
rs1311601941 1570 dbSNP
rs1207897807 1576 dbSNP
rs566351205 1579 dbSNP
rs893741852 1586 dbSNP
rs917714416 1604 dbSNP
rs1485849191 1607 dbSNP
rs1056220311 1613 dbSNP
rs929654615 1614 dbSNP
rs1203199777 1615 dbSNP
rs1032094969 1618 dbSNP
rs773843067 1624 dbSNP
rs1158705620 1630 dbSNP
rs1423845917 1633 dbSNP
rs1002001030 1640 dbSNP
rs974121330 1642 dbSNP
rs1178838913 1646 dbSNP
rs1376465871 1647 dbSNP
rs555062653 1656 dbSNP
rs962669543 1656 dbSNP
rs911095442 1667 dbSNP
rs905060280 1687 dbSNP
rs1323308015 1688 dbSNP
rs985313732 1690 dbSNP
rs183305716 1691 dbSNP
rs1029734599 1693 dbSNP
rs1282334174 1693 dbSNP
rs532717441 1694 dbSNP
rs1010258806 1697 dbSNP
rs1393399563 1701 dbSNP
rs1204109902 1705 dbSNP
rs1272200477 1706 dbSNP
rs1396140479 1706 dbSNP
rs1476725731 1706 dbSNP
rs76238618 1706 dbSNP
rs879065659 1706 dbSNP
rs1167165269 1708 dbSNP
rs199708916 1708 dbSNP
rs1372766672 1709 dbSNP
rs1297741836 1710 dbSNP
rs1323087933 1716 dbSNP
rs565451368 1719 dbSNP
rs1044871963 1730 dbSNP
rs1438624942 1736 dbSNP
rs1000572142 1739 dbSNP
rs906119440 1745 dbSNP
rs1045042100 1749 dbSNP
rs1295174568 1758 dbSNP
rs1341179528 1764 dbSNP
rs1196036952 1774 dbSNP
rs950187483 1775 dbSNP
rs1408304904 1809 dbSNP
rs1288648982 1810 dbSNP
rs1449380762 1813 dbSNP
rs1178536638 1816 dbSNP
rs867353733 1821 dbSNP
rs1187201306 1822 dbSNP
rs1253064760 1822 dbSNP
rs1470211021 1822 dbSNP
rs1392445125 1824 dbSNP
rs1475923989 1826 dbSNP
rs1388776597 1829 dbSNP
rs762742913 1829 dbSNP
rs1037050623 1836 dbSNP
rs1173654597 1843 dbSNP
rs940233687 1846 dbSNP
rs1387963522 1854 dbSNP
rs1434337629 1859 dbSNP
rs147260453 1860 dbSNP
rs868321643 1867 dbSNP
rs868008404 1868 dbSNP
rs1056247686 1869 dbSNP
rs867350795 1880 dbSNP
rs1227804867 1884 dbSNP
rs530579034 1892 dbSNP
rs1234743861 1897 dbSNP
rs1260655483 1898 dbSNP
rs563422215 1902 dbSNP
rs1207427087 1914 dbSNP
rs541800713 1917 dbSNP
rs1264394672 1923 dbSNP
rs1038046158 1925 dbSNP
rs149983840 1932 dbSNP
rs911179301 1941 dbSNP
rs1244396559 1942 dbSNP
rs1054748 1945 dbSNP
rs191923374 1951 dbSNP
rs1411352358 1958 dbSNP
rs965170558 1959 dbSNP
rs1318463762 1961 dbSNP
rs1261734579 1966 dbSNP
rs1241610129 1967 dbSNP
rs1382696511 1980 dbSNP
rs1317839864 1982 dbSNP
rs1021015239 1992 dbSNP
rs1306563209 1994 dbSNP
rs1222237059 2005 dbSNP
rs1293486961 2007 dbSNP
rs576745404 2009 dbSNP
rs987769048 2010 dbSNP
rs957914233 2016 dbSNP
rs1352124841 2019 dbSNP
rs988575241 2023 dbSNP
rs558291640 2025 dbSNP
rs956133909 2031 dbSNP
rs1488510569 2038 dbSNP
rs1405253438 2039 dbSNP
rs1265180110 2043 dbSNP
rs757257735 2046 dbSNP
rs139276887 2054 dbSNP
rs1161447009 2073 dbSNP
rs1364452776 2074 dbSNP
rs150822715 2076 dbSNP
rs1454284289 2078 dbSNP
rs1171880896 2090 dbSNP
rs1455159161 2091 dbSNP
rs905007527 2098 dbSNP
rs1399837908 2106 dbSNP
rs376452167 2111 dbSNP
rs141595260 2117 dbSNP
rs970456913 2117 dbSNP
rs1407612554 2118 dbSNP
rs1157948190 2121 dbSNP
rs1308570795 2159 dbSNP
rs751729220 2165 dbSNP
rs895921946 2173 dbSNP
rs1014498098 2176 dbSNP
rs80202510 2181 dbSNP
rs1437415689 2182 dbSNP
rs756539280 2183 dbSNP
rs1350504786 2202 dbSNP
rs1211969916 2205 dbSNP
rs1386601299 2208 dbSNP
rs939993337 2216 dbSNP
rs1444625577 2220 dbSNP
rs888485579 2247 dbSNP
rs1048657748 2251 dbSNP
rs1179137330 2253 dbSNP
rs993630601 2256 dbSNP
rs1432627884 2257 dbSNP
rs148792159 2258 dbSNP
rs146130621 2259 dbSNP
rs1436492530 2268 dbSNP
rs1041234001 2269 dbSNP
rs531736594 2273 dbSNP
rs1214781844 2274 dbSNP
rs538928730 2275 dbSNP
rs187000272 2278 dbSNP
rs913661098 2279 dbSNP
rs1385663777 2283 dbSNP
rs889436444 2300 dbSNP
rs550350457 2301 dbSNP
rs531983354 2302 dbSNP
rs1025295764 2305 dbSNP
rs569753692 2306 dbSNP
rs1297375715 2315 dbSNP
rs957699529 2317 dbSNP
rs1310528719 2320 dbSNP
rs1206929704 2322 dbSNP
rs933923566 2332 dbSNP
rs924974489 2341 dbSNP
rs1208200116 2345 dbSNP
rs922490867 2346 dbSNP
rs1385469232 2348 dbSNP
rs981084922 2352 dbSNP
rs1389339520 2363 dbSNP
rs765521727 2364 dbSNP
rs1025206478 2367 dbSNP
rs1172100384 2373 dbSNP
rs1013425180 2375 dbSNP
rs775520621 2379 dbSNP
rs960366962 2390 dbSNP
rs548008557 2393 dbSNP
rs529819033 2394 dbSNP
rs1015682672 2395 dbSNP
rs1004320923 2408 dbSNP
rs1320412656 2428 dbSNP
rs888434623 2429 dbSNP
rs181922683 2435 dbSNP
rs142922096 2440 dbSNP
rs377129136 2450 dbSNP
rs191159843 2451 dbSNP
rs564884609 2455 dbSNP
rs543201678 2456 dbSNP
rs759885671 2457 dbSNP
rs944212356 2460 dbSNP
rs113811687 2462 dbSNP
rs1247272794 2463 dbSNP
rs1484780793 2471 dbSNP
rs555022994 2473 dbSNP
rs1026526705 2474 dbSNP
rs1419960946 2479 dbSNP
rs1191944623 2482 dbSNP
rs185216408 2485 dbSNP
rs1419418361 2492 dbSNP
rs1292795332 2494 dbSNP
rs1159091793 2497 dbSNP
rs572518169 2500 dbSNP
rs936455261 2504 dbSNP
rs899320546 2509 dbSNP
rs1289857464 2517 dbSNP
rs1378869167 2518 dbSNP
rs924921985 2518 dbSNP
rs144634149 2521 dbSNP
rs879633544 2522 dbSNP
rs969673695 2524 dbSNP
rs1266305252 2532 dbSNP
rs1326950331 2532 dbSNP
rs1277393405 2534 dbSNP
rs1397931052 2538 dbSNP
rs539037396 2539 dbSNP
rs1217825978 2541 dbSNP
rs1303411588 2543 dbSNP
rs1242540007 2544 dbSNP
rs992522101 2547 dbSNP
rs1403897861 2556 dbSNP
rs745959040 2557 dbSNP
rs1259107685 2563 dbSNP
rs1169110711 2566 dbSNP
rs1049869229 2576 dbSNP
rs961852424 2578 dbSNP
rs1157859562 2584 dbSNP
rs1405122045 2595 dbSNP
rs1402998767 2620 dbSNP
rs571961358 2626 dbSNP
rs868136244 2643 dbSNP
rs373641406 2644 dbSNP
rs1433170588 2646 dbSNP
rs754135919 2648 dbSNP
rs1004269940 2651 dbSNP
rs763749929 2653 dbSNP
rs1169088751 2655 dbSNP
rs901138228 2655 dbSNP
rs1027360277 2664 dbSNP
rs1375597094 2666 dbSNP
rs750752734 2668 dbSNP
rs766936298 2670 dbSNP
rs1269992318 2671 dbSNP
rs1199038048 2680 dbSNP
rs1346900605 2682 dbSNP
rs556932554 2682 dbSNP
rs538420117 2683 dbSNP
rs1485816470 2685 dbSNP
rs1180973254 2705 dbSNP
rs1230698136 2706 dbSNP
rs1252838644 2708 dbSNP
rs1008919831 2716 dbSNP
rs865999740 2728 dbSNP
rs1196442641 2743 dbSNP
rs1338767312 2758 dbSNP
rs1257355156 2766 dbSNP
rs1042874458 2769 dbSNP
rs1376414609 2770 dbSNP
rs1429407569 2775 dbSNP
rs1461611252 2781 dbSNP
rs892623378 2788 dbSNP
rs1356386432 2804 dbSNP
rs1216682098 2810 dbSNP
rs1325449992 2817 dbSNP
rs1283656926 2821 dbSNP
rs1305413544 2822 dbSNP
rs1052566345 2826 dbSNP
rs567730845 2828 dbSNP
rs936402986 2831 dbSNP
rs1194901113 2835 dbSNP
rs1270360177 2841 dbSNP
rs549572591 2845 dbSNP
rs1439052794 2863 dbSNP
rs1204680660 2883 dbSNP
rs546949186 2883 dbSNP
rs1467559249 2884 dbSNP
rs1196029683 2888 dbSNP
rs1396095026 2892 dbSNP
rs1449203938 2893 dbSNP
rs1166376590 2903 dbSNP
rs903617473 2922 dbSNP
rs1391475677 2927 dbSNP
rs1045095118 2936 dbSNP
rs915962188 2952 dbSNP
rs1392346576 2957 dbSNP
rs1438649202 2960 dbSNP
rs1327788945 2962 dbSNP
rs1371460368 2966 dbSNP
rs781340467 2967 dbSNP
rs947740655 2967 dbSNP
rs960025630 2971 dbSNP
rs919542020 2976 dbSNP
rs529717779 2982 dbSNP
rs1272048408 2983 dbSNP
rs1466713325 2987 dbSNP
rs1254102319 2990 dbSNP
rs1195352072 2994 dbSNP
rs1191568711 3000 dbSNP
rs1244163517 3003 dbSNP
rs972295861 3007 dbSNP
rs868361264 3010 dbSNP
rs1016858286 3015 dbSNP
rs1463017316 3021 dbSNP
rs1167021250 3030 dbSNP
rs773896304 3033 dbSNP
rs992074339 3035 dbSNP
rs565772089 3040 dbSNP
rs547076225 3042 dbSNP
rs1007693252 3044 dbSNP
rs1471231177 3047 dbSNP
rs1316015256 3053 dbSNP
rs940600603 3062 dbSNP
rs953932193 3063 dbSNP
rs907683716 3064 dbSNP
rs532018707 3073 dbSNP
rs952738409 3074 dbSNP
rs1234527754 3077 dbSNP
rs1273257013 3104 dbSNP
rs1365777868 3109 dbSNP
rs1203874319 3113 dbSNP
rs763558664 3114 dbSNP
rs1447897473 3116 dbSNP
rs1437351513 3130 dbSNP
rs1236378463 3133 dbSNP
rs1476300117 3138 dbSNP
rs1196722160 3140 dbSNP
rs975941988 3143 dbSNP
rs137941983 3151 dbSNP
rs999198264 3153 dbSNP
rs1156697200 3163 dbSNP
rs1342543005 3170 dbSNP
rs1311910051 3171 dbSNP
rs1353242578 3174 dbSNP
rs904409309 3181 dbSNP
rs762521020 3183 dbSNP
rs543337991 3189 dbSNP
rs531521541 3190 dbSNP
rs1008406446 3191 dbSNP
rs1262942263 3193 dbSNP
rs527296016 3208 dbSNP
rs112513346 3218 dbSNP
rs1000998571 3222 dbSNP
rs865785977 3224 dbSNP
rs1334023588 3227 dbSNP
rs904066272 3230 dbSNP
rs775152838 3250 dbSNP
rs947822347 3262 dbSNP
rs769321601 3275 dbSNP
rs1159390724 3284 dbSNP
rs1440223813 3288 dbSNP
rs3192596 3292 dbSNP
rs1373369887 3307 dbSNP
rs1436223367 3309 dbSNP
rs1378585994 3317 dbSNP
rs953565835 3323 dbSNP
rs940548489 3335 dbSNP
rs572401202 3336 dbSNP
rs984740144 3337 dbSNP
rs1446428656 3343 dbSNP
rs1028060034 3360 dbSNP
rs554288568 3367 dbSNP
rs1243689094 3371 dbSNP
rs866751406 3381 dbSNP
rs1336937098 3382 dbSNP
rs997874163 3389 dbSNP
rs930459579 3401 dbSNP
rs1286024320 3411 dbSNP
rs111534556 3412 dbSNP
rs1250905697 3413 dbSNP
rs1031313685 3423 dbSNP
rs547881615 3424 dbSNP
rs1247557444 3426 dbSNP
rs1251331221 3434 dbSNP
rs1458197379 3439 dbSNP
rs578092383 3453 dbSNP
rs1393070383 3455 dbSNP
rs1019588846 3457 dbSNP
rs1284159042 3460 dbSNP
rs1042973961 3464 dbSNP
rs1372202032 3470 dbSNP
rs556618245 3472 dbSNP
rs73598914 3473 dbSNP
rs894298613 3474 dbSNP
rs180942662 3478 dbSNP
rs189426396 3482 dbSNP
rs1295292105 3490 dbSNP
rs1306052113 3493 dbSNP
rs1229846900 3494 dbSNP
rs1419396115 3515 dbSNP
rs1031207993 3529 dbSNP
rs150291047 3530 dbSNP
rs184916599 3532 dbSNP
rs897879586 3539 dbSNP
rs1024234517 3543 dbSNP
rs1260733994 3551 dbSNP
rs1011973332 3557 dbSNP
rs942040340 3565 dbSNP
rs909489774 3569 dbSNP
rs896224760 3570 dbSNP
rs1056107624 3582 dbSNP
rs1004542808 3586 dbSNP
rs886145100 3597 dbSNP
rs114657418 3600 dbSNP
rs930575782 3601 dbSNP
rs923461930 3602 dbSNP
rs1360248935 3604 dbSNP
rs1384165459 3617 dbSNP
rs113813836 3618 dbSNP
rs181476666 3626 dbSNP
rs190226382 3631 dbSNP
rs751035036 3635 dbSNP
rs1193616831 3641 dbSNP
rs1354916667 3643 dbSNP
rs1231588165 3654 dbSNP
rs1275117047 3656 dbSNP
rs1336906257 3671 dbSNP
rs965105100 3674 dbSNP
rs1259952349 3683 dbSNP
rs1283450749 3687 dbSNP
rs1469649671 3688 dbSNP
rs1187912267 3689 dbSNP
rs921758162 3696 dbSNP
rs1031341425 3712 dbSNP
rs1359564185 3717 dbSNP
rs549379091 3732 dbSNP
rs1039298748 3735 dbSNP
rs942761124 3736 dbSNP
rs1288504496 3737 dbSNP
rs1021988111 3742 dbSNP
rs1342076541 3745 dbSNP
rs531461071 3753 dbSNP
rs1271194635 3755 dbSNP
rs1158965109 3757 dbSNP
rs912647273 3759 dbSNP
rs986882606 3760 dbSNP
rs1299172782 3761 dbSNP
rs576539106 3761 dbSNP
rs1355132545 3763 dbSNP
rs1413126872 3765 dbSNP
rs1295250678 3769 dbSNP
rs956705430 3772 dbSNP
rs1228852032 3784 dbSNP
rs778030684 3785 dbSNP
rs979623348 3786 dbSNP
rs116673212 3788 dbSNP
rs1023764247 3798 dbSNP
rs1208251820 3799 dbSNP
rs567410720 3810 dbSNP
rs1472801568 3816 dbSNP
rs1012836556 3818 dbSNP
rs375466179 3829 dbSNP
rs76108913 3840 dbSNP
rs1406496110 3850 dbSNP
rs184476790 3851 dbSNP
rs1004658885 3867 dbSNP
rs1159666284 3878 dbSNP
rs1375195286 3879 dbSNP
rs1433114676 3881 dbSNP
rs886093004 3883 dbSNP
rs1359822663 3884 dbSNP
rs1421585417 3885 dbSNP
rs140404645 3905 dbSNP
rs887768335 3906 dbSNP
rs377072691 3912 dbSNP
rs1309776155 3915 dbSNP
rs1346820675 3934 dbSNP
rs1231630127 3940 dbSNP
rs994741693 3946 dbSNP
rs932250636 3949 dbSNP
rs1203288136 3953 dbSNP
rs923493186 3968 dbSNP
rs976221969 3971 dbSNP
rs1179753927 3979 dbSNP
rs900422026 3982 dbSNP
rs1038833216 3985 dbSNP
rs1452893112 3993 dbSNP
rs1245689391 4005 dbSNP
rs1426215428 4013 dbSNP
rs944532599 4015 dbSNP
rs1218721094 4017 dbSNP
rs1409605193 4018 dbSNP
rs192433394 4023 dbSNP
rs1051112473 4025 dbSNP
rs1448937245 4028 dbSNP
rs1274327794 4029 dbSNP
rs1331875258 4033 dbSNP
rs1218519121 4039 dbSNP
rs935428519 4047 dbSNP
rs977183404 4056 dbSNP
rs968812019 4065 dbSNP
rs1276390135 4067 dbSNP
rs1345323748 4084 dbSNP
rs1285556704 4089 dbSNP
rs563102590 4097 dbSNP
rs755148621 4100 dbSNP
rs1021308671 4110 dbSNP
rs7836186 4111 dbSNP
rs968293492 4112 dbSNP
rs1195970814 4115 dbSNP
rs1247625809 4121 dbSNP
rs1475237288 4127 dbSNP
rs369533490 4132 dbSNP
rs958614320 4133 dbSNP
rs1421782084 4135 dbSNP
rs147841124 4136 dbSNP
rs1355151233 4138 dbSNP
rs916808447 4139 dbSNP
rs1466154169 4143 dbSNP
rs1164285688 4145 dbSNP
rs1393728376 4146 dbSNP
rs766703652 4151 dbSNP
rs1465020477 4152 dbSNP
rs1421265743 4159 dbSNP
rs1002741456 4160 dbSNP
rs897649703 4165 dbSNP
rs1267979730 4174 dbSNP
rs145967867 4175 dbSNP
rs1433466009 4181 dbSNP
rs1424040907 4201 dbSNP
rs1189024923 4213 dbSNP
rs1006326311 4214 dbSNP
rs1238202259 4217 dbSNP
rs887833344 4219 dbSNP
rs1050459068 4220 dbSNP
rs1446745956 4221 dbSNP
rs1191319217 4222 dbSNP
rs1265687945 4225 dbSNP
rs532334808 4228 dbSNP
rs750867849 4230 dbSNP
rs1456798693 4239 dbSNP
rs79815374 4240 dbSNP
rs1474195809 4244 dbSNP
rs1040595028 4250 dbSNP
rs950466507 4251 dbSNP
rs1391190299 4264 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293T
Location of target site 3'UTR
Tools used in this research miRanda
Original Description (Extracted from the article) ... Verification of miR-122 target genes using 3'UTR reporter assay is shown in Supporting Table 4. ...

- Tsai WC; Hsu PW; Lai TC; Chau GY; Lin CW; et al., 2009, Hepatology (Baltimore, Md.).

Article - Tsai WC; Hsu PW; Lai TC; Chau GY; Lin CW; et al.
- Hepatology (Baltimore, Md.), 2009
UNLABELLED: MicroRNAs (miRNAs), which are inhibitors of gene expression, participate in diverse biological functions and in carcinogenesis. In this study, we show that liver-specific microRNA-122 (miR-122) is significantly down-regulated in liver cancers with intrahepatic metastasis and negatively regulates tumorigenesis. Restoration of miR-122 in metastatic Mahlavu and SK-HEP-1 cells significantly reduced in vitro migration, invasion, and anchorage-independent growth as well as in vivo tumorigenesis, angiogenesis, and intrahepatic metastasis in an orthotopic liver cancer model. Because an inverse expression pattern is often present between an miRNA and its target genes, we used a computational approach and identified multiple miR-122 candidate target genes from two independent expression microarray datasets. Thirty-two target genes were empirically verified, and this group of genes was enriched with genes regulating cell movement, cell morphology, cell-cell signaling, and transcription. We further showed that one of the miR-122 targets, ADAM17 (a disintegrin and metalloprotease 17) is involved in metastasis. Silencing of ADAM17 resulted in a dramatic reduction of in vitro migration, invasion, in vivo tumorigenesis, angiogenesis, and local invasion in the livers of nude mice, which is similar to that which occurs with the restoration of miR-122. CONCLUSION: Our study suggests that miR-122, a tumor suppressor microRNA affecting hepatocellular carcinoma intrahepatic metastasis by angiogenesis suppression, exerts some of its action via regulation of ADAM17. Restoration of miR-122 has a far-reaching effect on the cell. Using the concomitant down-regulation of its targets, including ADAM17, a rational therapeutic strategy based on miR-122 may prove to be beneficial for patients with hepatocellular carcinoma.
LinkOut: [PMID: 19296470]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

miRNA-target interactions (Provided by authors)
IDDuplex structurePosition
1 
miRNA  3' guuUGUGGUAACAGUGUGAGGu 5'
             |||:||||   :|||||| 
Target 5' ---ACAUCAUU---GCACUCCa 3'
 		1 - 16
Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000287263.4 | 3UTR | ACAUCAUUGCACUCCAGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.788 6.9e-4 0.698 4.0e-3 13 Click to see details
GSE28544 Breast cancer 0.595 1.1e-3 0.733 2.3e-5 24 Click to see details
GSE38226 Liver fibrosis -0.539 5.8e-3 -0.524 7.4e-3 21 Click to see details
GSE27834 Pluripotent stem cells 0.517 2.0e-2 0.450 4.0e-2 16 Click to see details
GSE21687 Ependynoma primary tumors -0.214 4.5e-2 -0.161 1.0e-1 64 Click to see details
GSE14794 Lymphoblastoid cells -0.139 9.6e-2 -0.165 6.0e-2 90 Click to see details
GSE26953 Aortic valvular endothelial cells -0.266 1.0e-1 -0.228 1.4e-1 24 Click to see details
GSE17498 Multiple myeloma -0.203 1.0e-1 -0.260 5.3e-2 40 Click to see details
GSE32688 Pancreatic cancer -0.211 1.2e-1 -0.276 6.3e-2 32 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.216 1.5e-1 0.159 2.2e-1 25 Click to see details
GSE17306 Multiple myeloma 0.126 1.9e-1 0.161 1.3e-1 49 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.338 2.6e-1 -0.257 3.1e-1 6 Click to see details
GSE42095 Differentiated embryonic stem cells 0.096 3.3e-1 0.432 2.0e-2 23 Click to see details
GSE19350 CNS germ cell tumors 0.075 4.1e-1 0.007 4.9e-1 12 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.046 4.2e-1 -0.023 4.6e-1 20 Click to see details
GSE21849 B cell lymphoma 0.031 4.4e-1 0.017 4.7e-1 29 Click to see details
GSE35602 Colorectal cancer stromal tissue 0.028 4.5e-1 0.071 3.7e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC -0.355 0.01 -0.413 0 49 Click to see details
STAD 0.804 0.01 0.833 0.01 8 Click to see details
HNSC -0.999 0.01 -1.000 0.5 3 Click to see details
ESCA 0.815 0.05 0.600 0.14 5 Click to see details
CHOL -0.397 0.15 -0.433 0.12 9 Click to see details
KIRP -0.326 0.2 -0.450 0.11 9 Click to see details
KIRC 0.117 0.27 0.117 0.27 29 Click to see details
KICH -0.063 0.44 0.048 0.46 8 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
THCA 0.063 0.46 0.300 0.31 5 Click to see details
MiRNA Regulatory Network:
Functional analysis:
Strong evidence (reporter assay, western blot, qRT-PCR or qPCR) Other evidence
Transcription factor regulation Circular RNA sponge
539 hsa-miR-122-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT000012 CYP7A1 cytochrome P450 family 7 subfamily A member 1 3 1
MIRT000364 IGF1R insulin like growth factor 1 receptor 4 3
MIRT000365 SRF serum response factor 4 1
MIRT000663 RAC1 Rac family small GTPase 1 5 2
MIRT000717 RHOA ras homolog family member A 2 2
MIRT003006 CCNG1 cyclin G1 4 4
MIRT003079 GTF2B general transcription factor IIB 2 1
MIRT003080 GYS1 glycogen synthase 1 4 2
MIRT003081 ANK2 ankyrin 2 3 1
MIRT003082 NFATC2IP nuclear factor of activated T-cells 2 interacting protein 3 1
MIRT003083 ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 4 2
MIRT003084 ANXA11 annexin A11 4 2
MIRT003085 ALDOA aldolase, fructose-bisphosphate A 3 2
MIRT003086 RAB6B RAB6B, member RAS oncogene family 3 1
MIRT003087 RAB11FIP1 RAB11 family interacting protein 1 5 3
MIRT003088 FOXP1 forkhead box P1 3 1
MIRT003089 MECP2 methyl-CpG binding protein 2 3 2
MIRT003090 NCAM1 neural cell adhesion molecule 1 4 3
MIRT003091 UBAP2 ubiquitin associated protein 2 3 1
MIRT003092 TBX19 T-box 19 3 1
MIRT003093 AACS acetoacetyl-CoA synthetase 3 1
MIRT003094 DUSP2 dual specificity phosphatase 2 3 1
MIRT003095 ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 3 1
MIRT003097 MAPK11 mitogen-activated protein kinase 11 3 1
MIRT003098 FUNDC2 FUN14 domain containing 2 3 1
MIRT003099 AKT3 AKT serine/threonine kinase 3 3 3
MIRT003100 TPD52L2 tumor protein D52 like 2 4 3
MIRT003102 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 4 2
MIRT003103 G6PC3 glucose-6-phosphatase catalytic subunit 3 4 2
MIRT003104 AP3M2 adaptor related protein complex 3 mu 2 subunit 3 1
MIRT003105 SLC7A1 solute carrier family 7 member 1 4 4
MIRT003106 XPO6 exportin 6 3 1
MIRT003107 FOXJ3 forkhead box J3 3 1
MIRT003108 SLC7A11 solute carrier family 7 member 11 3 1
MIRT003109 TRIB1 tribbles pseudokinase 1 3 1
MIRT003110 EGLN3 egl-9 family hypoxia inducible factor 3 3 1
MIRT003111 NUMBL NUMB like, endocytic adaptor protein 3 1
MIRT003112 ADAM17 ADAM metallopeptidase domain 17 3 5
MIRT003727 DSTYK dual serine/threonine and tyrosine protein kinase 3 2
MIRT003728 FAM117B family with sequence similarity 117 member B 3 1
MIRT004364 BCL2L2 BCL2 like 2 4 2
MIRT004527 PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1 2 1
MIRT004879 ADAM10 ADAM metallopeptidase domain 10 5 1
MIRT005782 ACVR1C activin A receptor type 1C 1 1
MIRT006123 PRKRA protein activator of interferon induced protein kinase EIF2AK2 4 1
MIRT006421 WNT1 Wnt family member 1 3 1
MIRT007007 PTPN1 protein tyrosine phosphatase, non-receptor type 1 1 1
MIRT007081 NT5C3A 5'-nucleotidase, cytosolic IIIA 1 1
MIRT007082 P4HA1 prolyl 4-hydroxylase subunit alpha 1 1 1
MIRT007083 ZNF395 zinc finger protein 395 1 1
MIRT007084 SOCS1 suppressor of cytokine signaling 1 1 1
MIRT023217 SSR3 signal sequence receptor subunit 3 1 1
MIRT023218 PHOX2A paired like homeobox 2a 1 1
MIRT023219 DZIP1L DAZ interacting zinc finger protein 1 like 1 1
MIRT023220 GSTM2 glutathione S-transferase mu 2 1 1
MIRT023221 RAI14 retinoic acid induced 14 1 1
MIRT023222 STARD13 StAR related lipid transfer domain containing 13 1 1
MIRT023223 CNN3 calponin 3 1 1
MIRT023224 A2M alpha-2-macroglobulin 1 1
MIRT023225 EFCAB6 EF-hand calcium binding domain 6 1 1
MIRT023226 GLOD4 glyoxalase domain containing 4 1 1
MIRT023227 CALR calreticulin 1 1
MIRT023228 POFUT1 protein O-fucosyltransferase 1 1 1
MIRT023229 PYGO1 pygopus family PHD finger 1 1 1
MIRT023230 CDY2B chromodomain Y-linked 2B 1 1
MIRT023231 CDC42EP3 CDC42 effector protein 3 1 1
MIRT023232 CS citrate synthase 3 3
MIRT023233 RNF170 ring finger protein 170 3 3
MIRT023234 GTF3C6 general transcription factor IIIC subunit 6 1 1
MIRT023235 ZNF321P zinc finger protein 321, pseudogene 1 1
MIRT023236 LAMP1 lysosomal associated membrane protein 1 1 1
MIRT023237 SLC52A2 solute carrier family 52 member 2 1 1
MIRT023238 ZNF658 zinc finger protein 658 1 1
MIRT023239 ATP13A3 ATPase 13A3 1 1
MIRT023240 CPNE5 copine 5 1 1
MIRT023241 KATNAL1 katanin catalytic subunit A1 like 1 1 1
MIRT023242 TMEM136 transmembrane protein 136 1 1
MIRT023243 ATP11A ATPase phospholipid transporting 11A 1 1
MIRT023244 TMEM74 transmembrane protein 74 1 1
MIRT023245 ANKRD10 ankyrin repeat domain 10 1 1
MIRT023246 TBL1XR1 transducin beta like 1 X-linked receptor 1 1 1
MIRT023247 USP10 ubiquitin specific peptidase 10 1 1
MIRT023248 AKAP11 A-kinase anchoring protein 11 1 1
MIRT023249 BACH2 BTB domain and CNC homolog 2 1 1
MIRT023250 HCCS holocytochrome c synthase 1 1
MIRT023251 Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1 1
MIRT023252 GTDC2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 1 1
MIRT023253 CTPS1 CTP synthase 1 1 1
MIRT023254 SLC44A1 solute carrier family 44 member 1 1 1
MIRT023255 CLSPN claspin 1 1
MIRT023256 RABGEF1 RAB guanine nucleotide exchange factor 1 1 1
MIRT023257 FBXO7 F-box protein 7 1 1
MIRT023258 NCDN neurochondrin 1 1
MIRT023259 SOX2 SRY-box 2 1 1
MIRT023260 ZNF618 zinc finger protein 618 1 1
MIRT023261 ABLIM1 actin binding LIM protein 1 1 1
MIRT023262 ZBTB4 zinc finger and BTB domain containing 4 1 1
MIRT023263 LUZP1 leucine zipper protein 1 1 1
MIRT023264 NLGN3 neuroligin 3 1 1
MIRT023265 PRR11 proline rich 11 1 1
MIRT023266 HHAT hedgehog acyltransferase 1 1
MIRT023267 UBE2L3 ubiquitin conjugating enzyme E2 L3 1 1
MIRT023268 DNAJC18 DnaJ heat shock protein family (Hsp40) member C18 1 1
MIRT023269 FAM102A family with sequence similarity 102 member A 1 1
MIRT023270 PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 1
MIRT023271 DENND2C DENN domain containing 2C 1 1
MIRT023272 HMOX1 heme oxygenase 1 3 2
MIRT023273 USP28 ubiquitin specific peptidase 28 1 1
MIRT023274 KRT18 keratin 18 1 1
MIRT023275 BPGM bisphosphoglycerate mutase 1 1
MIRT023276 ZNF233 zinc finger protein 233 1 1
MIRT023277 SLC25A30 solute carrier family 25 member 30 1 1
MIRT023278 ANKRD9 ankyrin repeat domain 9 3 3
MIRT023279 RLN1 relaxin 1 1 1
MIRT023280 DDIT3 DNA damage inducible transcript 3 1 1
MIRT023281 TRIM65 tripartite motif containing 65 1 1
MIRT023282 B4GALT1 beta-1,4-galactosyltransferase 1 1 1
MIRT023283 ANXA7 annexin A7 1 1
MIRT023284 SLC19A2 solute carrier family 19 member 2 1 1
MIRT023285 MARCKS myristoylated alanine rich protein kinase C substrate 1 1
MIRT023286 CLEC11A C-type lectin domain containing 11A 1 1
MIRT023287 CENPF centromere protein F 1 1
MIRT023288 CLDN18 claudin 18 1 1
MIRT023289 PFDN1 prefoldin subunit 1 1 1
MIRT023290 SPAG9 sperm associated antigen 9 1 1
MIRT023291 CEACAM8 carcinoembryonic antigen related cell adhesion molecule 8 1 1
MIRT023292 KRT10 keratin 10 1 1
MIRT023293 SET SET nuclear proto-oncogene 1 1
MIRT023294 SLC11A2 solute carrier family 11 member 2 1 1
MIRT023295 MYCBP MYC binding protein 3 3
MIRT023296 GPHB5 glycoprotein hormone beta 5 1 1
MIRT023297 STAU2 staufen double-stranded RNA binding protein 2 1 1
MIRT023298 NFATC1 nuclear factor of activated T-cells 1 1 1
MIRT023299 ERP29 endoplasmic reticulum protein 29 1 1
MIRT023300 MEP1A meprin A subunit alpha 1 1
MIRT023301 SPTLC1 serine palmitoyltransferase long chain base subunit 1 1 1
MIRT023302 GTF2H2 general transcription factor IIH subunit 2 1 1
MIRT023303 C14orf39 chromosome 14 open reading frame 39 1 1
MIRT023304 UBE2K ubiquitin conjugating enzyme E2 K 1 1
MIRT023305 PPP1R9B protein phosphatase 1 regulatory subunit 9B 1 1
MIRT023306 PSMD10 proteasome 26S subunit, non-ATPase 10 1 1
MIRT023307 CALD1 caldesmon 1 1 1
MIRT023308 TTYH3 tweety family member 3 1 1
MIRT023309 NMNAT2 nicotinamide nucleotide adenylyltransferase 2 1 1
MIRT023310 SCN4B sodium voltage-gated channel beta subunit 4 1 1
MIRT023311 C1orf122 chromosome 1 open reading frame 122 1 1
MIRT023312 PAK1 p21 (RAC1) activated kinase 1 1 1
MIRT023313 DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 1 1
MIRT023314 DMXL1 Dmx like 1 1 1
MIRT023315 ZNF160 zinc finger protein 160 1 1
MIRT023316 CSRP1 cysteine and glycine rich protein 1 1 1
MIRT023317 PHKA1 phosphorylase kinase regulatory subunit alpha 1 1 1
MIRT023318 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 1 1
MIRT023319 ANKRD13C ankyrin repeat domain 13C 1 1
MIRT023320 SUCLA2 succinate-CoA ligase ADP-forming beta subunit 1 1
MIRT023321 PEA15 phosphoprotein enriched in astrocytes 15 1 1
MIRT023322 MTPN myotrophin 1 1
MIRT023323 YKT6 YKT6 v-SNARE homolog 1 1
MIRT023324 MOB3B MOB kinase activator 3B 1 1
MIRT023325 FAM118A family with sequence similarity 118 member A 1 1
MIRT023326 ZNF264 zinc finger protein 264 1 1
MIRT023327 HECTD3 HECT domain E3 ubiquitin protein ligase 3 1 1
MIRT023328 BATF2 basic leucine zipper ATF-like transcription factor 2 1 1
MIRT023329 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha 1 1
MIRT023330 MAPRE1 microtubule associated protein RP/EB family member 1 1 1
MIRT023331 TBC1D22B TBC1 domain family member 22B 1 1
MIRT023332 SLC9A1 solute carrier family 9 member A1 3 3
MIRT023333 NPEPPS aminopeptidase puromycin sensitive 1 1
MIRT023334 BCL2L1 BCL2 like 1 2 1
MIRT023335 OSMR oncostatin M receptor 1 1
MIRT023336 CALU calumenin 1 1
MIRT023337 BRI3BP BRI3 binding protein 1 1
MIRT023338 PSPH phosphoserine phosphatase 1 1
MIRT023339 APMAP adipocyte plasma membrane associated protein 1 1
MIRT023340 WASF1 WAS protein family member 1 1 1
MIRT023341 LCA5 LCA5, lebercilin 1 1
MIRT023342 NODAL nodal growth differentiation factor 1 1
MIRT023343 CASP7 caspase 7 1 1
MIRT023344 CPA3 carboxypeptidase A3 1 1
MIRT023345 PALM paralemmin 1 1
MIRT023346 TCP11 t-complex 11 1 1
MIRT023347 NALCN sodium leak channel, non-selective 1 1
MIRT023348 PLAGL2 PLAG1 like zinc finger 2 1 1
MIRT023349 IDS iduronate 2-sulfatase 3 3
MIRT023350 PARP11 poly(ADP-ribose) polymerase family member 11 1 1
MIRT023351 MAZ MYC associated zinc finger protein 1 1
MIRT023352 CPNE4 copine 4 1 1
MIRT023353 FAM19A3 family with sequence similarity 19 member A3, C-C motif chemokine like 1 1
MIRT023354 KRT14 keratin 14 1 1
MIRT023355 DYNC1H1 dynein cytoplasmic 1 heavy chain 1 1 1
MIRT023356 GNL3L G protein nucleolar 3 like 1 1
MIRT023357 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1 1
MIRT023358 EYA4 EYA transcriptional coactivator and phosphatase 4 1 1
MIRT023359 GNPDA2 glucosamine-6-phosphate deaminase 2 1 1
MIRT023360 BRCA2 BRCA2, DNA repair associated 1 1
MIRT023361 ZSCAN4 zinc finger and SCAN domain containing 4 1 1
MIRT023362 HSPA5 heat shock protein family A (Hsp70) member 5 1 1
MIRT023363 SERAC1 serine active site containing 1 1 1
MIRT023364 SLC15A2 solute carrier family 15 member 2 1 1
MIRT023365 RABIF RAB interacting factor 1 1
MIRT023366 ART3 ADP-ribosyltransferase 3 1 1
MIRT023367 EP400 E1A binding protein p400 1 1
MIRT023368 MT4 metallothionein 4 1 1
MIRT023369 TRAM2 translocation associated membrane protein 2 1 1
MIRT023370 PHPT1 phosphohistidine phosphatase 1 1 1
MIRT023371 KIAA0101 PCNA clamp associated factor 1 1
MIRT023372 VHL von Hippel-Lindau tumor suppressor 1 1
MIRT023373 IFNA1 interferon alpha 1 1 1
MIRT023374 FSTL3 follistatin like 3 1 1
MIRT023375 PHF14 PHD finger protein 14 1 1
MIRT023376 ZCCHC2 zinc finger CCHC-type containing 2 1 1
MIRT023377 GSTM3 glutathione S-transferase mu 3 1 1
MIRT023378 DCTN5 dynactin subunit 5 1 1
MIRT023379 CHST3 carbohydrate sulfotransferase 3 1 1
MIRT023380 HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 1 1
MIRT023381 ADO 2-aminoethanethiol dioxygenase 1 1
MIRT023382 POMZP3 POM121 and ZP3 fusion 1 1
MIRT023383 CHST12 carbohydrate sulfotransferase 12 1 1
MIRT023384 ARSB arylsulfatase B 1 1
MIRT023385 ATP7A ATPase copper transporting alpha 1 1
MIRT023386 PMP22 peripheral myelin protein 22 1 1
MIRT023387 TGFBRAP1 transforming growth factor beta receptor associated protein 1 1 1
MIRT023388 ORC2 origin recognition complex subunit 2 1 1
MIRT023389 CREB1 cAMP responsive element binding protein 1 1 1
MIRT023390 CD83 CD83 molecule 1 1
MIRT023391 TOB2 transducer of ERBB2, 2 3 5
MIRT023392 LRP11 LDL receptor related protein 11 1 1
MIRT023393 MPV17 MPV17, mitochondrial inner membrane protein 1 1
MIRT023394 TRIM29 tripartite motif containing 29 1 1
MIRT023395 OSBP2 oxysterol binding protein 2 1 1
MIRT023396 PKM pyruvate kinase, muscle 6 4
MIRT023397 FOXK2 forkhead box K2 3 3
MIRT023398 CLIC4 chloride intracellular channel 4 5 6
MIRT023399 ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 1 1
MIRT023400 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1 1
MIRT023401 LMNB2 lamin B2 3 5
MIRT023402 BAX BCL2 associated X, apoptosis regulator 2 2
MIRT023403 CDK4 cyclin dependent kinase 4 3 3
MIRT054362 Cux1 cut-like homeobox 1 1 1
MIRT074336 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT109185 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT324745 ACER2 alkaline ceramidase 2 2 2
MIRT325564 HIATL1 major facilitator superfamily domain containing 14B 2 4
MIRT438005 MEF2D myocyte enhancer factor 2D 1 2
MIRT438206 TGFB1 transforming growth factor beta 1 1 1
MIRT438639 AXL AXL receptor tyrosine kinase 1 1
MIRT438655 NOD2 nucleotide binding oligomerization domain containing 2 3 1
MIRT438734 FUT8 fucosyltransferase 8 3 1
MIRT449879 CYP3A5 cytochrome P450 family 3 subfamily A member 5 2 2
MIRT451716 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT453274 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT454113 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT454232 OSBPL10 oxysterol binding protein like 10 2 15
MIRT454344 CDKL1 cyclin dependent kinase like 1 2 2
MIRT455826 ZSWIM1 zinc finger SWIM-type containing 1 2 3
MIRT459903 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 12
MIRT461654 G6PC glucose-6-phosphatase catalytic subunit 2 2
MIRT461934 TNFSF14 TNF superfamily member 14 2 2
MIRT463834 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT468615 SUMO1 small ubiquitin-like modifier 1 2 2
MIRT469456 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT469637 RAD21 RAD21 cohesin complex component 2 6
MIRT473432 MDM4 MDM4, p53 regulator 2 2
MIRT473872 MAFK MAF bZIP transcription factor K 2 6
MIRT476861 FHL2 four and a half LIM domains 2 2 4
MIRT476893 FBXO21 F-box protein 21 2 2
MIRT479880 CCDC43 coiled-coil domain containing 43 2 2
MIRT488848 UBTF upstream binding transcription factor, RNA polymerase I 2 2
MIRT491164 LRP3 LDL receptor related protein 3 2 2
MIRT497662 PRMT3 protein arginine methyltransferase 3 2 2
MIRT499314 ZNF485 zinc finger protein 485 2 10
MIRT499759 CIRH1A UTP4, small subunit processome component 2 10
MIRT500014 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501090 SLC7A5 solute carrier family 7 member 5 2 4
MIRT509646 ZNF354B zinc finger protein 354B 2 10
MIRT509945 TOMM70A translocase of outer mitochondrial membrane 70 2 6
MIRT510320 SLC2A3 solute carrier family 2 member 3 2 4
MIRT515505 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT516410 COPA coatomer protein complex subunit alpha 2 2
MIRT517861 NCAPD2 non-SMC condensin I complex subunit D2 2 4
MIRT522558 MCAM melanoma cell adhesion molecule 2 4
MIRT523525 GLUL glutamate-ammonia ligase 2 2
MIRT523764 FBXO27 F-box protein 27 2 4
MIRT524517 CDK19 cyclin dependent kinase 19 2 2
MIRT524753 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT529366 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 2 4
MIRT531189 SIGLEC12 sialic acid binding Ig like lectin 12 (gene/pseudogene) 2 2
MIRT531639 C19orf52 translocase of inner mitochondrial membrane 29 2 4
MIRT531913 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT532678 PATZ1 POZ/BTB and AT hook containing zinc finger 1 2 2
MIRT533115 YIPF4 Yip1 domain family member 4 2 4
MIRT534740 RBM47 RNA binding motif protein 47 2 2
MIRT535471 PARVB parvin beta 2 4
MIRT536742 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT537237 GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2 2
MIRT539523 ABCF1 ATP binding cassette subfamily F member 1 2 4
MIRT540438 RBM43 RNA binding motif protein 43 2 2
MIRT542982 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT544674 AP1S1 adaptor related protein complex 1 sigma 1 subunit 2 2
MIRT549514 HDDC2 HD domain containing 2 2 2
MIRT549663 ORC6 origin recognition complex subunit 6 2 4
MIRT555420 PPIC peptidylprolyl isomerase C 2 2
MIRT564701 ZNF322P1 zinc finger protein 322 pseudogene 1 2 2
MIRT570046 PKNOX1 PBX/knotted 1 homeobox 1 2 2
MIRT570257 PRSS16 protease, serine 16 2 2
MIRT571143 HM13 histocompatibility minor 13 2 2
MIRT575202 Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 2 2
MIRT575282 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 2 2
MIRT575302 Osbpl10 oxysterol binding protein-like 10 2 9
MIRT575323 Fbxo6 F-box protein 6 2 2
MIRT575377 Ang angiogenin, ribonuclease, RNase A family, 5 2 3
MIRT575614 Zswim1 zinc finger SWIM-type containing 1 2 3
MIRT575671 Map1b microtubule-associated protein 1B 2 2
MIRT607065 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 2 2
MIRT607490 HEBP2 heme binding protein 2 2 2
MIRT607522 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT607655 BTN3A2 butyrophilin subfamily 3 member A2 2 2
MIRT607795 RHBDL2 rhomboid like 2 2 2
MIRT607842 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT607927 ANG angiogenin 2 3
MIRT607966 SNX22 sorting nexin 22 2 2
MIRT608074 ZFP14 ZFP14 zinc finger protein 2 2
MIRT608141 SYAP1 synapse associated protein 1 2 2
MIRT612620 RABL3 RAB, member of RAS oncogene family like 3 2 2
MIRT617444 CCS copper chaperone for superoxide dismutase 2 2
MIRT617552 MTO1 mitochondrial tRNA translation optimization 1 2 2
MIRT618772 HLA-E major histocompatibility complex, class I, E 2 2
MIRT618926 MEAF6 MYST/Esa1 associated factor 6 2 2
MIRT619247 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT620091 YME1L1 YME1 like 1 ATPase 2 2
MIRT620483 XKR6 XK related 6 2 2
MIRT620570 WBSCR27 methyltransferase like 27 2 4
MIRT622977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT623169 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT624165 DGKE diacylglycerol kinase epsilon 2 2
MIRT625268 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT625396 AKR7L aldo-keto reductase family 7 like (gene/pseudogene) 2 2
MIRT625694 OPTN optineurin 2 2
MIRT626093 MKLN1 muskelin 1 2 2
MIRT626431 CHDH choline dehydrogenase 2 2
MIRT627013 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
MIRT627077 SF3A1 splicing factor 3a subunit 1 2 2
MIRT627140 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT627347 TSHZ2 teashirt zinc finger homeobox 2 2 2
MIRT627420 THAP2 THAP domain containing 2 2 2
MIRT627441 TAS2R5 taste 2 receptor member 5 2 2
MIRT628078 KAT7 lysine acetyltransferase 7 2 4
MIRT628276 CYB5D1 cytochrome b5 domain containing 1 2 2
MIRT629094 F2RL1 F2R like trypsin receptor 1 2 2
MIRT629236 CINP cyclin dependent kinase 2 interacting protein 2 2
MIRT629286 UNC13A unc-13 homolog A 2 2
MIRT629407 ADM2 adrenomedullin 2 2 2
MIRT629584 RFC2 replication factor C subunit 2 2 2
MIRT629635 WDR31 WD repeat domain 31 2 2
MIRT629874 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT629984 NARS asparaginyl-tRNA synthetase 2 2
MIRT630043 TERF2 telomeric repeat binding factor 2 2 2
MIRT630061 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT630127 ARHGEF5 Rho guanine nucleotide exchange factor 5 2 2
MIRT630155 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT630252 SMTNL2 smoothelin like 2 2 2
MIRT630278 PSMB5 proteasome subunit beta 5 2 2
MIRT630347 NKAP NFKB activating protein 2 2
MIRT630497 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT631264 CENPM centromere protein M 2 2
MIRT631403 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT632470 RPS15A ribosomal protein S15a 2 2
MIRT632596 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT632994 DUSP18 dual specificity phosphatase 18 2 2
MIRT633082 CXorf21 chromosome X open reading frame 21 2 2
MIRT633239 ZNF573 zinc finger protein 573 2 2
MIRT633286 SLC1A5 solute carrier family 1 member 5 2 2
MIRT633536 PGBD5 piggyBac transposable element derived 5 2 2
MIRT634338 SGOL1 shugoshin 1 2 2
MIRT634600 KIAA1919 major facilitator superfamily domain containing 4B 2 2
MIRT635050 MYH11 myosin heavy chain 11 2 2
MIRT635236 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT635322 BMS1 BMS1, ribosome biogenesis factor 2 2
MIRT636268 RNF157 ring finger protein 157 2 2
MIRT636450 LRCH3 leucine rich repeats and calponin homology domain containing 3 2 2
MIRT636516 FMN1 formin 1 2 2
MIRT636755 SLC16A5 solute carrier family 16 member 5 2 2
MIRT637134 BAMBI BMP and activin membrane bound inhibitor 2 2
MIRT637188 ROMO1 reactive oxygen species modulator 1 2 2
MIRT637287 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT637532 RGS9BP regulator of G protein signaling 9 binding protein 2 2
MIRT637693 CEP89 centrosomal protein 89 2 2
MIRT637788 OLA1 Obg like ATPase 1 2 2
MIRT637925 LILRA2 leukocyte immunoglobulin like receptor A2 2 2
MIRT638449 PLXDC2 plexin domain containing 2 2 2
MIRT640871 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT642643 PTGR2 prostaglandin reductase 2 2 2
MIRT643082 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643123 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT644236 SLC35E3 solute carrier family 35 member E3 2 2
MIRT644665 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT645092 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT645993 ACP6 acid phosphatase 6, lysophosphatidic 2 2
MIRT646508 FAM217B family with sequence similarity 217 member B 2 2
MIRT647013 ADCY2 adenylate cyclase 2 2 2
MIRT647095 SEC23B Sec23 homolog B, coat complex II component 2 2
MIRT647714 NFX1 nuclear transcription factor, X-box binding 1 2 4
MIRT648040 FADS6 fatty acid desaturase 6 2 2
MIRT648510 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT648865 ABCA6 ATP binding cassette subfamily A member 6 2 2
MIRT649182 DNPEP aspartyl aminopeptidase 2 2
MIRT649660 TEP1 telomerase associated protein 1 2 2
MIRT651465 XIAP X-linked inhibitor of apoptosis 2 2
MIRT652398 TMEM40 transmembrane protein 40 2 2
MIRT653691 SLC25A33 solute carrier family 25 member 33 2 2
MIRT654122 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654577 PXMP4 peroxisomal membrane protein 4 2 2
MIRT656470 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT658905 DPY19L4 dpy-19 like 4 2 2
MIRT660878 ADRBK2 G protein-coupled receptor kinase 3 2 4
MIRT661101 SPIB Spi-B transcription factor 2 2
MIRT661238 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT661291 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT662235 PGBD4 piggyBac transposable element derived 4 2 2
MIRT662544 MTAP methylthioadenosine phosphorylase 2 2
MIRT662736 LRRC3C leucine rich repeat containing 3C 2 2
MIRT662844 OMD osteomodulin 2 2
MIRT662907 MED18 mediator complex subunit 18 2 2
MIRT662956 JPH2 junctophilin 2 2 2
MIRT663340 ZNF74 zinc finger protein 74 2 2
MIRT663496 IYD iodotyrosine deiodinase 2 2
MIRT663523 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT663542 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663903 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT663973 ZNF786 zinc finger protein 786 2 2
MIRT664350 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT664417 TIGD6 tigger transposable element derived 6 2 2
MIRT664468 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT664957 PTCD3 pentatricopeptide repeat domain 3 2 2
MIRT664970 TDRD1 tudor domain containing 1 2 2
MIRT665199 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 2
MIRT665359 XKR4 XK related 4 2 2
MIRT665454 WDR17 WD repeat domain 17 2 2
MIRT665486 VPS53 VPS53, GARP complex subunit 2 2
MIRT666078 SSTR2 somatostatin receptor 2 2 2
MIRT666258 SLC31A1 solute carrier family 31 member 1 2 2
MIRT666324 SLC16A10 solute carrier family 16 member 10 2 2
MIRT666486 SBNO1 strawberry notch homolog 1 2 2
MIRT666696 RBM23 RNA binding motif protein 23 2 2
MIRT666712 RBL1 RB transcriptional corepressor like 1 2 2
MIRT666762 RAB10 RAB10, member RAS oncogene family 2 2
MIRT666931 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT667226 NFE2L1 nuclear factor, erythroid 2 like 1 2 2
MIRT667359 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT667474 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT667558 LRAT lecithin retinol acyltransferase 2 2
MIRT667748 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 2
MIRT668088 GMEB1 glucocorticoid modulatory element binding protein 1 2 2
MIRT668119 GK5 glycerol kinase 5 (putative) 2 2
MIRT668166 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT668346 STXBP2 syntaxin binding protein 2 2 2
MIRT668509 ESYT2 extended synaptotagmin 2 2 2
MIRT669291 C17orf85 nuclear cap binding subunit 3 2 2
MIRT669547 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT669778 CNDP1 carnosine dipeptidase 1 2 2
MIRT669858 BROX BRO1 domain and CAAX motif containing 2 4
MIRT670017 TECPR1 tectonin beta-propeller repeat containing 1 2 2
MIRT670177 CCDC142 coiled-coil domain containing 142 2 2
MIRT671107 ZNF841 zinc finger protein 841 2 2
MIRT671351 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 2
MIRT671476 FLYWCH2 FLYWCH family member 2 2 2
MIRT671492 SLC38A9 solute carrier family 38 member 9 2 2
MIRT671554 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT671925 PLEKHS1 pleckstrin homology domain containing S1 2 4
MIRT672196 F2 coagulation factor II, thrombin 2 2
MIRT672217 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT672252 SIK2 salt inducible kinase 2 2 2
MIRT672290 GP2 glycoprotein 2 2 2
MIRT672430 POLR2D RNA polymerase II subunit D 2 2
MIRT672597 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT672901 KRBA2 KRAB-A domain containing 2 2 2
MIRT672958 ZNF655 zinc finger protein 655 2 2
MIRT673096 SYNPO2L synaptopodin 2 like 2 2
MIRT673171 TMEM56 transmembrane protein 56 2 2
MIRT673251 INO80 INO80 complex subunit 2 2
MIRT673296 RNF19B ring finger protein 19B 2 2
MIRT673574 KDELC2 KDEL motif containing 2 2 2
MIRT673586 KIF1C kinesin family member 1C 2 2
MIRT673737 TCF23 transcription factor 23 2 2
MIRT673767 MRPL17 mitochondrial ribosomal protein L17 2 2
MIRT674215 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674283 NAGK N-acetylglucosamine kinase 2 2
MIRT674338 KCMF1 potassium channel modulatory factor 1 2 2
MIRT674517 PRR23A proline rich 23A 2 2
MIRT675100 SNTB2 syntrophin beta 2 2 2
MIRT675144 MOGAT1 monoacylglycerol O-acyltransferase 1 2 4
MIRT675223 CLK4 CDC like kinase 4 2 2
MIRT675263 ZNF431 zinc finger protein 431 2 2
MIRT675577 WWC1 WW and C2 domain containing 1 2 2
MIRT676025 C9orf69 transmembrane protein 250 2 2
MIRT676430 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT676560 VSIG1 V-set and immunoglobulin domain containing 1 2 2
MIRT676596 ARIH2OS ariadne RBR E3 ubiquitin protein ligase 2 opposite strand 2 2
MIRT678576 TMEM168 transmembrane protein 168 2 2
MIRT678756 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT680344 ZNF281 zinc finger protein 281 2 2
MIRT680467 C3 complement C3 2 2
MIRT682826 FLG2 filaggrin family member 2 2 2
MIRT682881 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT684404 TMEM180 major facilitator superfamily domain containing 13A 2 2
MIRT685275 KIAA1143 KIAA1143 2 2
MIRT686061 KCNA7 potassium voltage-gated channel subfamily A member 7 2 2
MIRT687526 NASP nuclear autoantigenic sperm protein 2 2
MIRT691760 BCL2L15 BCL2 like 15 2 2
MIRT693890 C3orf62 chromosome 3 open reading frame 62 2 2
MIRT699342 SLC35E1 solute carrier family 35 member E1 2 2
MIRT699909 RUNDC1 RUN domain containing 1 2 2
MIRT700536 PTPDC1 protein tyrosine phosphatase domain containing 1 2 2
MIRT701807 MRPS25 mitochondrial ribosomal protein S25 2 2
MIRT702174 LYRM4 LYR motif containing 4